- 2019
- 低侵襲プラズマ止血機器の安全性に関する国際標準とその意義
榊田 創、池原 譲
J. Plasma Fusion Res. 95(4) 173-179, 2019
http://www.jspf.or.jp/Journal/PDF_JSPF/jspf2019_04/jspf2019_04-173.pdf
Synthesis of endohedral-fullerenes using laser ablation plasma from solid
material and vaporized fullerenes.
H. Itagaki, Y. Fujiwara Y. Minowa, Y. Ikehara, T. Kaneko, T. Okazaki, Y.
Iizumi, J. Kim, H. Sakakita
AIP Advances 9(7) 075324, 2019
https://doi.org/10.1063/1.5100980
TGF-β signaling promotes tube-structure-forming growth in pancreatic duct
adenocarcinoma.
Yamaguchi T, Ikehara S, Akimoto Y, Nakanishi H, Kume M, Yamamoto K, Ohara
O, Ikehara Y
Sci Rep. 2019 Aug 2;9(1):11247.
https://doi.org/10.1038/s41598-019-47101-y
Systematic diagnostics of the electrical, optical, and physicochemical
characteristics of low-temperature atmospheric-pressure helium plasma sources.
Takeda K, Yamada H, Ishikawa K, Sakakita H, Kim J, Ueda M, Ikeda J, Akimoto
Y, Kataoka Y, Yokoyama N, Ikehara Y, Hori M.
Journal of Physics D: Applied Physics. 52(16), 2019
https://doi.org/10.1088/1361-6463/aaff44
A measurement method for determining the correlation between the amount
of haemolysis and the electric current in low-temperature plasma treatment.
Miyamoto K, Ikehara Y.
Plasma Processes and Polymers, 16(5), 1800142, 2019
https://doi.org/10.1002/ppap.201800142
Cover Picture: https://onlinelibrary.wiley.com/doi/abs/10.1002/ppap.201970011
- 2018
- Biparametric Prostate Imaging Reporting and Data System version2 and International
Society of Urological Pathology Grade Predict Biochemical Recurrence after
Radical Prostatectomy.
Takeuchi N, Sakamoto S, Nishiyama A, Horikoshi T, Yamada Y, Iizuka J, Maimaiti
M, Imamura Y, Kawamura K, Imamoto T, Komiya A, Ikehara Y, Akakura K, Ichikawa
T.
Clin Genitourin Cancer. 2018 Feb 24. pii: S1558-7673(18)30127-7.
https://doi.org/10.1016/j.clgc.2018.02.011
Plasma Medical Innovation for Cancer Therapy: Cancer Initiating Cells.
Ikeda JI, Tanaka H, Sakakita H, Ishikawa K, Ikehara Y, Hori M.
Chapter 5.10, Plasma Medical Science, 309-12, Academic Press 2018
Introduction for Chapter 6. Chapter 6.1.
Shimizu N and Ikehara Y.
Plasma Medical Science, 321, Academic Press 2018
Cutting-Edge Technologies of Bleeding Control Using Nonthermal Plasma－Mechanism
of Blood Coagulation and Wound Healing.
Miyamoto K, Ikehara Y, Ikehara S, Akimoto Y, Sakakita H, Ishikawa K, Ueda
M, Ikeda JI, Nakanishi H, Shimizu N, Shimizu T, Hori M.
Plasma Medical Science, Chapter 6.2, 322-8 Academic Press 2018
Clinical Efficacy of Nonthermal Plasma Treatment in Minimally Invasive
Gastrointestinal Surgery.
Shimizu N, Seto Y, Sakakita H, Ikehara Y.
Plasma Medical Science, Chapter 6.3, 329-35 Academic Press 2018
Molecular Morphological Analysis of The Effect of Plasma Irradiation on
Cells, Tissue. Plasma Medical Science.
Akimoto Y, Ikehara S, Yamaguchi T, Kim, J Kawakami H, Shimizu N, Hori M,
Sakakita H, Ikehara Y.
Chapter 6.4, 336-43 Academic Press 2018
Evaluating the Invasiveness of Nonthermal Plasma Treatment Using Molecular
Imaging Technique.
Ueda M, Yamagami D, Temma T, Koshino K, Goto O, Ikeda JI, Sakakita H, Ishikawa
K, Hori M, Shimizu N, Ikehara Y.
Plasma Medical Science, Chapter 6.5, 344-52 Academic Press 2018
Tanaka A, Hirata T, Sakakita H, Ikehara Y.
Introduction for Chapter 7
Plasma Medical Science, Chapter 7.1, 387-9 Academic Press 2018
General Concepts of Basic Safety on Plasma Treatment.
Tanaka A, Koga K, Kitazaki S, Akimoto Y, Ikehara Y.
Plasma Medical Science, Chapter 7.2, 390-400 Academic Press 2018
International Standardization.
Sakakita H, Ikehara Y, Kim J, Shimizu N, Watanabe S, Shimizu T, Antoni
V.
Plasma Medical Science, Chapter 7.4, 409-414, Academic Press 2018
Medical Electrical equipment - Part 2-76: Particular requirements for the
basic safety and essential performance or ionized gas coagulation equipment.
IEC TC 62/SC 62D/Working Group 34(Yuzuru Ikehara is an expert in WG34).
IEC 60601-2-76: 2018. May 1
Measurements of emission-propagation phenomena in low-energy atmospheric-
pressure helium plasma.
Yamada, Hiromasa; Shimizu, Tetsuji; Fujiwara, Masanori; Kato, Susumu; Fujiwara,
Yutaka; Itagaki, Hirotomo; Kiyama, Satoru; Kim, Jaeho; Ikehara, Sanae;
Shimizu, Nobuyuki; Nakanishi, Hayao; Ikehara, Yuzuru; Sakakita, H.
Plasma Sources Science and Technology, Volume 27, Number 5. Published 14
May 2018.
- 2017
- Effect of plasma-activated medium on the decrease of tumorigenic population
in lymphoma.
Wada N, Ikeda JI, Tanaka H, Sakakita H, Hori M, Ikehara Y, Morii E.
Pathol Res Pract. 2017 Jul;213(7):773-777. doi: 10.1016/j.prp.2017.04.003.
Glycobiomarker, Fucosylated Short-Form Secretogranin III Levels Are Increased
in Serum of Patients with Small Cell Lung Carcinoma.
Togayachi A, Iwaki J, Kaji H, Matsuzaki H, Kuno A, Hirao Y, Nomura M, Noguchi
M, Ikehara Y, Narimatsu H.
J Proteome Res. 2017 Dec 1;16(12):4495-4505.
ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of
colorectal cancer via the Akt pathway.
Ogawa T, Hirohashi Y, Murai A, Nishidate T, Okita K, Wang L, Ikehara Y,
Satoyoshi T, Usui A, Kubo T, Nakastugawa M, Kanaseki T, Tsukahara T, Kutomi
G, Furuhata T, Hirata K, Sato N, Mizuguchi T, Takemasa I, Torigoe T.
Oncotarget 2017 8(68):112550-112564. doi: 10.18632/oncotarget.22545.
Dynamics of erythrocyte indices in relation to anemia development in Theileria
orientalis-infected cattle.
Sivakumar T, Ikehara Y, Igarashi I, Inokuma H, and Yokoyama N.
The Journal of Protozoology Research 2017 27. 23-33.
Plasma -activated medium (PAM) kills human cancer-initiating cells.
Ikeda JI, Tanaka H, Ishikawa K, Hajime S, Ikehara Y, and Hori M.
Pathology Int. 2017 68 (1), p 23–30. Doi: 10.1111/pin.12617
Crystallization of calcium oxalate dihydrate in a buffered calcium-containing
glucose solution by irradiation with non-equilibrium atmospheric pressure
plasma.
Kurake N, Tanaka H, Ishikawa K, Nakamura K, Kajiyama H, Kikkawa F, Mizuno
M, Ikehara Y, and Hori M.
C Journal of Applied Physics 2017 122 (14) 143301.
【総説・書籍】
低侵襲プラズマ止血機器の開発
榊田創、池原譲、清水信幸、山田大将
高度物理刺激と生体応用 2017養賢堂 1(1)123-125
Benefits of applying low-temperature plasma treatment to wound care and
hemostasis from the viewpoints of physics and pathology.
Shimizu T and Ikehara Y.
Journal of Physics D: Applied Physics. 50(50) 2017. 503001
- 2016
- Myosin light chain 9 and 12 are functional ligands for CD69 that regulate
airway inflammation.
Hayashizaki K, Kimura M Y, Tokoyoda K, Hosokawa H, Shinoda K, Hirahara
K, Ichikawa T, Onodera A, Hanazawa A, Iwamura C, Kakuta J, Muramoto K,
Motohashi S, Tumes D J, Iinuma T, Yamamoto H, Ikehara Y, Okamoto Y, and
Nakayama T.
Sci. Immunol.2016.Sep; 1（3）.9154.
Bending and turbulent enhancement phenomena of neutral gas flow containing
an atmospheric pressure plasma by applying external electric fields measured
by schlieren optical method.
Yamada H, Yamagishi Y, Sakakita H, Tsunoda S, Kasahara J, Fujiwara M, Kato
S, Itagaki H, Kim J, Kiyama S, Fujiwara Y, Ikehara Y, Ikehara S, Nakanishi
H, and Shimizu N.
Japanese Journal of Applied Physics. 2016; 55(01AB08): 1-5.
Observations of multiple stationary striation phenomena in an atmospheric
pressure neon plasma jet.
Fujiwara Y, Sakakita H, Yamada H, Yamagishi Y, Itagaki H, Kiyama S, Fujiwara
M, Ikehara Y, and Kim J.
Japanese Journal of Applied Physics. 2016; 55(010301); 1-3.
Spectroscopy of reactive species produced by low-energy atmospheric-pressure
plasma on conductive target material surface.
Yamada H, Sakakita H, Yamagishi Y, Kato S, Kim J, Kiyama S, Fujiwara M,
Itagaki H, Okazaki T, Ikehara S, Nakanishi H, Shimizu N, Ikehara Y.
Journal of Applied Physics. 2016; Volume 49, Number 39
A novel glycobiomarker, Wisteria floribunda agglutinin Macrophage Colony-Stimulating
Factor Receptor, for predicting carcinogenesis of liver cirrhosis.
Iio E, Ocho M, Togayachi A, Nojima M, Kuno A, Ikehara Y, Hasegawa I, Yatsuhashi
H, Yamasaki K, Shimada N, Ide T, Shinkai N, Nojiri S, Fujiwara K, Joh T,
Mizokami M, Narimatsu H, Tanaka Y.
Int J Cancer. 2016; 138(6):1462–1471. doi: 10.1002/ijc.29880
Formation of fibroblastic reticular network in the brain after infection
with neurovirulent murine coronavirus.
Watanabe R, Kakizaki M, Ikehara Y, Togayachi A.
Neuropathology. 2016 In press doi: 10.1111/neup.12302.
Evaluation of fluorescence imaging with indocyanine green in hepatocellular
carcinoma.
Kaibori M*, Matsui K, Ishizaki M, Iida H, Sakaguchi T, Tsuda T, Okumura
T, Inoue K, Shimada S, Ohtsubo S, Kusano M, Ikehara Y, Ozeki E, KitawakiT
and Kon M . Cancer.
Imaging. 2016:16(6).doi: 10.1186/s40644-016-0064-62016.
Red Blood Cell Coagulation Induced by Low-temperature Plasma Treatment.
Miyamoto K, Ikehara S, Takei H, Akimoto Y, Sakakida H, Ishikawa K, Ueda
M, Ikeda J, Yamagishi M, Kim J, Yamaguchi T, Nakanishi H, Shimizu N, Hori
M, Ikehara Y.
Archives of Biochemistry and Biophysics. 2016; Available online 28 March
2016. doi:10.1016/j.abb.2016.03.023.Archives of Biochemistry and Biophysics.
Galectin expression in healing wounded skin treated with low-temperature
plasma: Comparison with treatment by electronical coagulation.
Akimoto Y, Ikehara S, Yamaguchi T, Kim J, Hayato Kawakami, Nobuyuki Shimizu,
Masaru Hori, Hajime Sakakita, Ikehara Y.
Archives of Biochemistry and Biophysics. 2016 Sep 1;605:86-94. doi: 10.1016/j.abb.2016.01.012.
Epub 2016 Jan 28..
【総説・書籍】
低温プラズマ技術を取り入れた手術用止血装置.
宮本 健司,池原 早苗,榊田 創,池原 譲.
応用物理 85(9), 793-796, 2016-09.応用物理学会
Low temperature plasma equipment applied on surgical hemostasis and wound
healing.
Miyamoto K, Ikehara S, Sakakita H,Ikehara Y. Journal of Clinical Biochemistry
and Nutrition (JCBN).
Released: December 17, 2016/ Vol. 60 (2017) No. 1 p.25-28
Catastrophic hypothesisによる膵発癌 — ヒト膵癌とマウスモデル膵癌 —
山口 高志, 池原 早苗, 池原 譲.
臨床消化器内科 2016;Vol.31 No.13(5-1)
- 2015
- Study on Thermal Characteristics of Ionized Gas Coagulation Equipment.
Kim J, Sakakita H, Yamada H, Ikehara S, Nakanishi H, Niwa T, Shimizu N,
Ichinose M, Ikehara Y.
Plasma Medicine. 5(2–4): 99–108 (2015)
Anti-Cancer Effects of Nonequilibrium Atmospheric Pressure Plasma on Cancer-Initiating
Cells in Human Endometrioid Adenocarcinoma Cell.
Jun-Ichiro Ikeda,*, Yoko Tsuruta, Satoshi Nojima, Hajime Sakakita, Masaru
Hori and Yuzuru Ikehara.
Plasma Processes and Polymers.Volume 12, Issue 12, pages 1370–1376, December
2015DOI: 10.1002/ppap.201500097
Plasma blood coagulation without involving the activation of platelets
and coagulation factors .
Ikehara S, Sakakita H,Ishikawa K, Yamaguchi T, Kim J,Ueda M, Ikeda J,Nakanishi
H,Shimizu N,Hori M, Ikehara Y.
Plasma Processes and Polymers.Volume 12, Issue 12, pages 1348–1353, December
2015.
Comparison of intratumoral heterogeneity of HER2 expression between primary
tumor and multiple organ metastases in gastric cancer: Clinicopathological
study of three autopsy cases and one resected case.
Saito T, Kondo C, Shitara K, Ito Y, Saito N, Ikehara Y, Yatabe Y, Yamamichi
K, Tanaka T, Nakanishi H.
Pathol Int, 2015 Jun;65(6):309-17. doi: 10.1111/pin.12290. Epub 2015 Mar
31.
Lectin microarray technology identifies specific lectins related to lymph
node metastasis of advanced gastric cancer.
Yamashita K, Kuno A, Matsuda A, Ikehara Y, Katada N, Hirabayashi J, Narimatsu
H, Watanabe M.
Gastric Cancer. 2016 Apr;19(2):531-542. doi: 10.1007/s10120-015-0491-2.
Epub 2015 Apr 4.
Lectin Microarray-Based Sero-Biomarker Verification Targeting Aberrant
O-Linked Glycosylation on Mucin 1.
Matsuda A, Kuno A, Nakagawa T, Ikehara Y, Irimura T, Yamamoto M, Nakanuma
Y, Miyoshi E, Nakamori S, Nakanishi H, Viwatthanasittiphong C, Srivatanakul
P, Miwa M, Shoda J, Narimatsu H.
Anal Chem. 2015 Jul 21;87(14):7274-81. doi: 10.1021/acs.analchem.5b01329.
Epub 2015 Jul 7.
Preparation and Functionalization of Boron Nitride Containing Carbon Nanohorns
for Boron Neutron Capture Therapy.
Iizumi Y, Okazaki T, Zhang M, Yuge R, Ichihashi T., Nakamura M, Ikehara
Y, Iijima S, Yudasaka M.
Carbon. 2015 Nov. Vol. 93 pp. 595-603. 10.1016/j.carbon.2015.05.085
Verification of WFA-Sialylated MUC1 as a Sensitive Biliary Biomarker for
Human Biliary Tract Cancer. Yamaguchi T, Yokoyama Y, Ebata T, Matsuda A,
Kuno A, Ikehara Y, Shoda J, Narimatsu H, Nagino M.
Ann Surg Oncol. 2015 Sep 28.
Histological and Nuclear Medical Comparison of Inflammation After Hemostasis
with Non-Thermal Plasma and Thermal Coagulation.
Ueda M., Yamagami D., Watanabe K., Mori A, Kimura H., Sano K., Saji H.,
Ishikawa K., Hori M., Sakakita H., Ikehara Y, and Enomoto S.
Plasma Processes and Polymers. Volume 12, Issue 12, pages 1338–1342, December
2015.DOI: 10.1002/ppap.201500099
【総説・書籍】
オミックス解析技術 1.最近のオミックス解析技術の進歩 6)糖鎖解析技術の進歩で実現される糖鎖情報の解読と病態理解
糖鎖構造の解析は,質量分析器の進歩が推進してきた。このことにより,均一に見える培養細胞などの細胞集団にも,多様な糖鎖構造が存在することが明らかとなっている。質量分析器の進歩で読み解かれる糖鎖構造の多様性とその変化は,腫瘍などの疾患の発症と進展,疾患に随伴する病態の成り立ちに関連づけられてゆくことと思う。本稿では,このような視点に立ち糖鎖解析技術の進歩で実現されるバイオマーカー研究を考察する。
(著者抄録)
池原 譲
遺伝子医学MOOK No.29 P.94-99.2015
- 2014
- Glycoproteomics approach for identifying Glycobiomarker candidate molecules
for tissue type classification of non-small cell lung carcinoma.
Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe
M,Nomura M, Noguchi M, Ikehara Y, Narimatsu H.
J Proteome Res. 2014 Nov 7;13(11):4705-16.
A genetically engineered mouse model developing rapid progressive pancreatic ductal
adenocarcinoma
Yamaguchi T, Ikehara S, Nakanishi H, IkeharaY. The Journal of Pathology
Volume 234, Issue 2, pages 228–238, October 2014
Mice lacking α1,3-fucosyltransferase 9 exhibit modulation of in vivo immune
responses against pathogens.
Kashiwazaki H, Kakizaki M, Ikehara Y, Togayachi A, Narimatsu H, Watanabe
R.
Pathol Int.64(5):199-208. doi: 10.1111/pin.12159.
Synthesis and evaluation of a radioiodinated peptide probe targeting avb6
integrin for the detection of pancreatic ductaladenocarcinoma.
Masashi Ueda , Takahiro Fukushima , Kei Ogawa , Hiroyuki Kimura , Masahiro
Ono ,Takashi Yamaguchi , Yuzuru Ikehara , Hideo Saji.
Biochemical and Biophysical Research Communications.445 Issue 3,(2014)
661-666 2014 Mar 14 ,
Novel Glycobiomarker for Ovarian Cancer That Detects ClearCell Carcinoma.
SogabeM, Nozaki H, Tanaka N, Kubota T, Kaji H, Kuno A, Togayachi A, Gotoh
M,Nakanishi H, Nakanishi T, Mikami M, Suzuki N, Kiguchi K,Ikehara Y, Narimatsu
H.
J Proteome Res. 2014 Mar 7;13(3):1624-35.doi: 10.1021/pr401109n.
Application of a Glycoproteomics-Based Biomarker Development Method: Alteration
in Glycan Structure on Colony Stimulating Factor 1 Receptor as a Possible
Glycobiomarker Candidate for Evaluation of Liver Cirrhosis.
Ocho M, Togayachi A, Iio E, Kaji H, Kuno A, Sogabe M, Korenaga M, Gotoh
M, Tanaka Y,Ikehara Y, Mizokami M, Narimatsu H.
J Proteome Res. 2014 Mar 7;13(3):1428-37. doi: 10.1021/pr400986t
【総説・書籍】
出血制御における従来手法と低温プラズマ法の比較
低温プラズマは,大量の失血原因とはならないような出血を対象に,組織に焼灼や熱傷を生じることなく,生じた血液凝固物によって出血部を閉塞し,止血することができる。高周波電気凝固止血装置など,出血点を焼きつぶして止血するタイプの器具(総じて,エネルギーデバイスと呼ばれる)を用いて手術をすると,熱による組織障害,いわゆる外科手術後の障害,すなわち術後障害と呼ばれるものが発生する。止血を目的に使用されているプラズマ技術にアルゴンプラズマ凝固装置(APC)他があるが,これらを止血目的で使用しても,止血に伴う侵襲性は依然としてある。プラズマによる血液凝固として,40度以上の高温状態に至ることなく安定なGlow‐likeプラズマを発生できる装置を開発し,医療用デバイスとしての実用化を進めている。
池原 譲
静電気学会誌 Vol.38 No.4 P.171-176 .2014
糖鎖情報から読み解く、生命活動と病理
池原 譲
「病理と臨床」32(6),677-681.2014
Mouse Models of Cancer.
Ikehara Y., Yamaguchi T., Ikehara S.
Glycoscience: Biology and Medicine DOI 10.1007/978-4-431-54836-2_194-1
- 2013
- α2-3 Sialic acid glycoconjugate loss and its effect on infectionwith Toxoplasma
parasites.
Nishikawa Y, Ogiso A, Kameyama K, Nishimura M, Xuan X,IkeharaY. Exp Parasitol.
2013 Nov;135(3):479-85. doi: 10.1016/j.exppara.2013.08.009. Epub 2013 Aug
27.
C1galt1-deficient mice exhibit thrombocytopenia due toabnormal terminal
differentiation of megakaryocytes.
Kudo T, Sato T, Hagiwara K, Kozuma Y, Yamaguchi T,Ikehara Y, Hamada M,
Matsumoto K, Ema M, Murata S, Ohkohchi N, Narimatsu H, Takahashi S.
Blood. 2013 Aug 29;122(9):1649-57. doi: 10.1182/blood-2012-12-471102. Epub
2013 Jun 21.
Immunoassay with Single-Walled Carbon Nanotubes as Near-Infrared Fluorescent
Labels.
Iizumi Y, Okazaki T, Ikehara Y., Ogura M, Fukata S, Yudasaka M .
ACS Appl Mater Interfaces. 2013, 5 7665-7670. [PMID:23927721]
Formation of membrane-like structures in clotted blood by mildplasma treatment
during hemostasis.
Ikehara Y., Sakakita H., Shimizu N., Ikehara S., Nakanishi, H.
2013, 26(4), 555-557, Journal of Photopolymer Science and Technology .
Establishment and characterization of novel gastric signet-ringcell and
non signet-ring cell poorly differentiated adenocarcinomacell lineswith
low and high malignant potential. Murakami H, Nakanishi H, Tanaka H,Ito
S, Misawa K, Ito Y, Ikehara Y, Kondo E, Kodera Y. Gastric Cancer.Jan;16(1):74-83
2013
A serum "sweet-doughnut" protein facilitates fibrosis evaluationand
therapyassessment in patients with viral hepatitis.
Kuno A,Ikehara Y, Tanaka Y, Ito K, Matsuda A, Sekiya S, Hige S, Sakamoto
M,Kage M, Mizokami M, Narimatsu H.
Sci Rep. 2013;3:1065. doi: 10.1038/srep01065.
Podocalyxin Is a Glycoprotein Ligand of the Human PluripotentStem Cell-Specific
ProberBC2LCN.
Tateno H, Matsushima A, Hiemori K, Onuma Y, Ito Y, Hasehira K, Nishimura
K,Ohtaka M, Takayasu S, Nakanishi M, Ikehara Y, Nakanishi M, Ohnuma K,
Chan T,Toyoda M, Akutsu H, Umezawa A, Asashima M, Hirabayashi.
J. Stem Cells Transl Med. 2013 Apr;2(4):265-73. doi: 10.5966/sctm.2012-0154.
Glycoproteomic Discovery of Serological Biomarker Candidates for HCV/HBVInfection-Associated
Liver Fibrosis and HepatocellularCarcinoma.
Kaji H, Ocho M, Togayachi A, Kuno A, Sogabe M, Ohkura T, Nozaki H, Angata
T,Chiba Y, Ozaki H, Hirabayashi J, Tanaka Y, Mizokami M, Ikehara Y, NarimatsuH.
J Proteome Res. 2013 Apr 30.
Glycoproteomics-based cancer marker discovery adopting dual enrichment
withWisteria floribunda agglutinin for high specific glyco-diagnosis ofcholangiocarcinoma.
Matsuda A, Kuno A, Matsuzaki H, Kawamoto T, Shikanai T, Nakanuma Y, YamamotoM,
Ohkohchi N, Ikehara Y, Shoda J, Hirabayashi J, Narimatsu H. J Proteomics.
2013 Apr 21. doi:pii: S1874-3919(13)00206-6.10.1016/j.jprot.2013.04.017.
Reconstruction of a robust glycodiagnostic agent supported bymultiplelectin-assisted
glycan profiling.
Kuno A, Sato T, Shimazaki H, Unno S, Saitou K, Kiyohara K, Sogabe M, TsurunoC,
Takahama Y,Ikehara Y, Narimatsu H.
Proteomics Clin Appl. 2013 May 3. doi: 10.1002/prca.201300010.
- 2012
- LecT-Hepa, a glyco-marker derived from multiple lectins, asapredictor of
liver fibrosis in chronic hepatitis C patients.
Ito K, Kuno A,Ikehara Y, Sugiyama M, Saito H, Aoki Y,Matsui T, Imamura
M, Korenaga M, Murata K, Masaki N, Tanaka Y, Hige S, Izumi N,Kurosaki M,
Nishiguchi S, Sakamoto M, Kage M, Narimatsu H, Mizokami M.
Hepatology. 2012 Apr 26. doi:10.1002/hep.25815.
Establishment and characterization of novel gastric signet-ring celland
non signet-ring cell poorly differentiated adenocarcinomacell lines withlow
and high malignant potential.
Murakami H, Nakanishi H, Tanaka H, Ito S, Misawa K, Ito Y,Ikehara Y, Kondo
E, Kodera Y.
GastricCancer. 2012 Mar 27. [Epub ahead of print]
PCR Detection of Babesia ovata from Cattle Reared in JapanandClinical Significance
of Co-Infection with Theileria orientalis.
Sivakumar T, Tagawa M, Yoshinari T, Ybañez AP, Igarashi I,Ikehara Y, Hata
H, Kondo S, Matsumoto K, Inokuma H, Yokoyama N.
J Clin Microbiol. 2012 Mar 21. [Epub ahead of print]
Different Levels of Sialyl-Tn Antigen Expressed on MUC16 inPatientsWith
Endometriosis and Ovarian Cancer.
Akita K, Yoshida S,Ikehara Y, Shirakawa S, Toda M, InoueM, Kitawaki J,
Nakanishi H, Narimatsu H, Nakada H.
IntJ Gynecol Cancer. 2012 May;22(4):531-8.
Enhancement of metastatic ability by ectopic expression ofST6GalNAcIon
a gastric cancer cell line in a mouse model.
Ozaki H, Matsuzaki H, Ando H, Kaji H, Nakanishi H,IkeharaY, Narimatsu H.
Clin Exp Metastasis.
2012Mar;29(3):229-38. Epub 2012 Jan 8
Comparisonof LecT-Hepa and FibroScan for assessment of liver fibrosis in
hepatitis B virusinfected patients with different ALT levels.
Du D, Zhu X, Kuno A, MatsudaA, Tsuruno C, Yu D, Zhang Y, Ikehara Y, Tanaka
Y, Zhang X, Narimatsu H.
ClinChim Acta. 2012 Nov;413(21-22):1796-1799
Identification of Core Proteins Carrying the Sialyl Lewis aEpitopein Pancreatic
Cancers.
Hirao Y, Ogasawara S, Togayachi A, MatsunoY, Ocho M, Yamashita K, Watanabe
M, Nakamori S,Ikehara Y, Narimatsu H.
J MolBiomark Diagn. 3(3)
- 2011
- Single-walled carbon nanohorns as drug carriers: adsorption ofprednisolone
andanti-inflammatory effects onarthritis. Nakamura M,Tahara Y,Ikehara Y,
Murakami T, Tsuchida K, Iijima S, Waga I,YudasakaM. Nanotechnology. 2011
Nov 18;22(46):465102. Epub 2011 Oct 25
Characterization of SplenicCells during the Early Phase ofInfection withNeuropathogenic
Mouse Hepatitis Virus. Kashiwazaki H,Taguchi F,Ikehara Y,Watanabe R.
Jpn J Infect Dis. 201164(3):256-9
LecT-Hepa: A triplex lectin-antibody sandwich immunoassay for estimating
the progression dynamics of liver fibrosis assisted by a bedside clinical
chemistry analyzer and an automated pretreatment machine.
KunoA, IkeharaY, Tanaka Y, Saito K, Ito K, Tsuruno C, Nagai S, Takahama
Y,Mizokami M,Hirabayashi J, Narimatsu H.
Clin Chim Acta. 2011 Sep 18;412(19-20):1767-72
Expression and role of 3'-phosphoadenosine 5'-phosphosulfatetransportersin
human colorectal carcinoma.
Kamiyama S, Ichimiya T,Ikehara Y, Takase T, Fujimoto I,Suda T, Nakamori
S, Nakamura M, Nakayama F, Irimura T, Nakanishi H, Watanabe M,Narimatsu
H, Nishihara S.
Glycobiology. 2011 Feb;21(2):235-46.
Chondroitin sulfateN-acetylgalactosaminyltransferase 1 is necessary for normal
endochondral ossification and aggrecan metabolism.
Sato T, Kudo T,Ikehara Y,Ogawa H, Hirano T, Kiyohara K, Hagiwara K,Togayachi
A, Ema M,Takahashi S,Kimata K, Watanabe H, Narimatsu H.
J Biol Chem. 2011Feb 18;286(7):5803-12
Development of defective and persistent sendai virus vector: a unique gene
delivery/expression system ideal for cell reprogramming.
Nishimura K, Sano M,Ohtaka M, Furuta B, Umemura Y, Nakajima Y,Ikehara Y,
Kobayashi T, SegawaH, Takayasu S, Sato H, Motomura K, Uchida E, Kanayasu-Toyoda
T, Asashima M,Nakauchi H, Yamaguchi T, Nakanishi M.
J Biol Chem.2011 Feb 11;286(6):4760-71.
Multi-lectin assay for detecting fibrosis-specific glyco-alterationby means
of lectin microarray.
Kuno A,Ikehara Y, Tanaka Y, Angata T, Unno S, Sogabe M, Ozaki H, Ito K,Hirabayashi
J, Mizokami M and Narimatsu H.
Clinical Chem. 2011Jan;57(1):48-56.
【総説・書籍】
糖鎖分析技術を取り入れた組織細胞化学研究 組織細胞化学2011年度講習会テキスト -見るバイオサイエンスー基礎から最先端技術まで
池原 譲
日本組織細胞化学会編集p155-166, 2011
- 2010
- Wisteria floribunda agglutinin-positive MUC1 is a sensitive biliary marker
for human cholangiocarcinoma.
Matsuda M., KunoA., Kawamoto T., Matsuzaki H., Irimura T.,Ikehara Y., Zen
Y., NakanumaY., Yamamoto M., Ohkohchi N., Shoda J., Hirabayashi J., and
Narimatsu H.
Hepatology. 2010 Jul;52(1):174-82, 2010.
Cytopathy of an infiltrating monocyte lineage during the early phase of
infection with murinecoronavirus in the brain.
Takatsuki H, Taguchi F, Nomura R, Kashiwazaki H,Watanabe M,Ikehara Y,Watanabe
R.Neuropathology.
2010 Aug; 30(4): 361-71.
Lack of lacto/neolacto-glycolipids enhances the formation of glycolipid-enriched
microdomains, facilitating B cell activation.
Togayachi A, Kozono Y,Ikehara Y, Ito H,Suzuki N, Tsunoda Y, Abe S, Sato
T, Nakamura K, Suzuki M, Goda HM, Ito M,Kudo T, Takahashi S, Narimatsu
H.
Proc Natl Acad Sci U S A.2010Jun 29; 107(26):11900-5
Targeted delivery of oligomannose-coated liposometo the omental micrometastasis
by peritoneal macrophages from patientswith gastric cancer.
Matsui M, Shimizu Y, Kodera Y, Kondo E,Ikehara Y, Nakanishi H.
Cancer Sci .2010 Jul; 101(7):1670-7
Irradiation experiments on a mouse using a mild-plasma generator for medical
applications.
Hajime Sakakita and Yuzuru Ikehara.
Plasma and Fusion Research, 2010 S2117, 1-4
Generation of IFN-gamma-producing cells that recognize the major piroplasm
surface protein in Theileria orientalis-infected bovines.
Yamaguchi T, Yamanaka M, Ikehara S, Kida K, Kuboki N, Mizuno D, Yokoyama
N, Narimatsu H, Ikehara Y.
Veterinary Parasitology, 2010 Aug 4;171(3-4):207-15
Neospora caninum: Application of apical membrane antigen 1 encapsulated
in the oligomannose-coated liposomes for reduction ofoffspring mortality
from infection in BALB/c mice.
Zhang H, Nishikawa Y, Yamagishi J,Zhou J,Ikehara Y, Kojima N, Yokoyama
N, Xuan X.
Exp Parasitol. 2010 Jun;125(2):130-6
【総説・書籍】
Differential glycan profiling by lectin microarray targeting tissuespecimens.
Kuno A, Matsuda A, Ikehara Y., Narimatsu H, Hirabayashi J.
Methods Enzymol. 2010;478:165-79.
Beta3GnT2 (B3GNT2), a major polylactosamine synthase: analysis ofB3GNT2-deficient
mice.
Togayachi A, Kozono Y, Kuno A,Ohkura T, Sato T, Hirabayashi J,Ikehara Y.,Narimatsu
H.
Methods Enzymol. 2010;479:185-204.
グライコプロテオミクスによるがんの血清バイオマーカー探索 創薬・タンパク質研究のためのプロテオミクス解析.
梶 裕之、池原 譲、久野 敦、澤木 弘道、伊藤 浩美、成松 久
験医学別冊 p112-118, 2010.
-組織細胞化学イメージングの基礎と最前線
池原 譲
組織細胞化学2010年度講習会テキスト：生体内分子局在と機能を探る-日本組織細胞化学会編集 糖鎖・糖タンパク質の生物機能解明と医療応用 197-204,
2010
血液検査で肝炎の進行度がわかる---疾患糖鎖マーカーによる診断治療の革新
池原 譲
産総研TODAY Vol.10(2010) No.03、産総研、2010/03/01
Recent advancements in cytotoxic T lymphocyte generation methods usingcarbohydrate-coated
liposomes.
Ikehara Y,Yamanaka M,Yamaguchi T.
J Biomed Biotechnol. 2010;2010:242539. Epub 2010 Jun17.PMID: 20617143
A strategy for discovery of cancer glyco-biomarkers in serumusing newly
developed technologies for glycoproteomics.
Narimatsu H., Sawaki H., Kuno A., Kaji H., Ito H., and IkeharaY.
FEBSJournal, 277(1): 95-105, 2010
Vaccine development based onoligomannose-coated liposome against Neospora
vertical transmission.
Nishikawa, Y., Zhang, H., Ikehara, Y., Kojima,N., Yokoyama, N., and Xuan,
X.
Jpn. J. Vet. Parasitol.8(125),2010
Experimental infection of Theileria orientalis incattle.
Khukhuu, A., de Macedo, A. C. C., Yamamoto, H.,Igarashi, I., Kobayashi,
Y., Kida, H., Inokuma, H.,Ikehara, Y., andYokoyama, N.
Jpn. J. Vet. Parasitol.9(69),2010