Research Achievements
Yoshitaka Okamoto| 2012 | 2011 | 2010 | 2009 | 2008 |
| Papers| Books| International Conferences |
Papers
Fuse M‚ Kojima S‚ Enokida H‚ Chiyomaru T‚ Yoshino H‚ Nohata N‚ Kinoshita T‚ Sakamoto S‚ Naya Y‚ Nakagawa M‚ Ichikawa T‚ Seki N. Tumor suppressive microRNAs (miR-222 and miR-31) regulate molecular pathways based on microRNA expression signature in prostate cancer.
J Hum Genet. 2012; in press
Kinoshita T‚ Hanazawa T‚ Nohata N‚ Okamoto Y‚ Seki N. The functional significance of microRNA-375 in human squamous cell carcinoma: aberrant expression and effects on cancer pathways.
J Hum Genet. 2012; 57 (9): 556-563
Yonekura S‚ Okamoto Y‚ Shimojo N‚ Yamamoto H‚ Sakurai D‚ Horiguchi S‚ Hanazawa T‚ Inoue Y‚ Arima T‚ Tomiita M‚ Kohno Y. The onset of allergic rhinitis in Japanese atopic children: A preliminary prospective study.
Acta Otolaryngol. 2012; 132 (9): 981-987
Yamamoto H‚ Yonekura S‚ Sakurai D‚ Inamine A‚ Sakurai T‚ Iinuma T‚ Horiguchi S‚ Okamoto Y . Comparison of nasal steroid with anti-histamine in prophylactic treatment against pollinosis using an environmental challenge chamber.
Allergy and Asthma Proceeding 2012; 33 (5): 397-403
Katada K‚Tomonaga T‚ Satoh M‚ Matsushita K‚ Tonoike Y‚ Kodera Y‚ Hanazawa T‚ Nomura F‚ Okamoto Y. Plectin promotes migration and invasion of cancer cells and is a novel probnostic marker for head and neck squamous cell carcinoma.
Journal of Proteomics. 2012; in press
Yamasaki T‚ Seki N‚ Yamada Y‚ Yoshino H‚ Hidaka H‚ Chiyomaru T‚ Nohata N‚ Kinoshita T‚ Nakagawa M‚ Enokida H. Tumor suppressive microRNA‑138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma.
Int J Oncol. 2012; in press
Isozaki Y‚ Hoshino I‚ Nohata N‚ Kinoshita T‚ Akutsu Y‚ Hanari N‚ Mori M‚ Yoneyama Y‚ Akanuma N‚ Takeshita N‚ Maruyama T‚ Seki N‚ Nishino N‚ Yoshida M‚ Matsubara H. Identification of novel molecular targets regulated by tumor suppressive miR-375 induced by histone acetylation in esophageal squamous cell carcinoma.
Int J Oncol. 2012; in press
Kinoshita T‚ Hanazawa T‚ Nohata N‚ Okamoto Y‚ Seki N. The functional significance of microRNA-375 in human squamous cell carcinoma: aberrant expression and effects on cancer pathways.
J Hum Genet. 2012; in press
Yamasaki T‚ Yoshino H‚ Enokida H‚ Hidaka H‚ Chiyomaru T‚ Nohata N‚ Kinoshita T‚ Fuse M‚ Seki N‚ Nakagawa M. Novel molecular targets regulated by tumor suppressors microRNA-1 and microRNA-133a in bladder cancer.
Int J Oncol. 2012; 40 (6): 1821-1830
Kinoshita T‚ Nohata N‚ Yoshino H‚ Hanazawa T‚ Kikkawa N‚ Fujimura L‚ Chiyomaru T‚ Kawakami K‚ Enokida H‚ Nakagawa M‚ Okamoto Y‚ Seki N. microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma.
Int J Oncol. 2012; 40 (1): 185-193
Hidaka H‚ Seki N‚ Yoshino H‚ Yamasaki T‚ Yamada Y‚ Nohata N‚ Fuse M‚ Nakagawa M‚ Enokida H. Tumor suppressive microRNA-1285 regulates novel molecular targets: aberrant expression and functional significance in renal cell carcinoma.
Oncotarget. Review 2012; 1 44-57
Kinoshita T‚ Nohata N‚ Watanabe-Takano H‚ Yoshino H‚ Hidaka H‚ Fujimura L‚ Fuse M‚ Yamasaki T‚ Enokida H‚ Nakagawa M‚ Hanazawa T‚ Okamoto Y‚ Seki N. Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma.
Int J Oncol. 2012; 40 (6): 1770-1778
Nohata N‚ Hanazawa T‚ Enokida H‚ Seki N. microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers.
Oncotarget. Review 2012; 3 (1): 9-21
Kinoshita T‚ Nohata N‚ Fuse M‚ Hanazawa T‚ Kikkawa N‚ Fujimura L‚ Watanabe-Takano H‚ Yamada Y‚ Yoshino H‚ Enokida H‚ Nakagawa M‚ Okamoto Y‚ Seki N. Tumor suppressive microRNA-133a regulates novel targets: moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma.
Biochem Biophys Res Commun. 2012; 418 (2): 378-383
Inamine A‚ Sakurai D‚ Horiguchi S‚ Yonekura S‚ Hanazawa T‚ Hosokawa H‚ Matuura-Suzuki A‚ Nakayama T‚ Okamoto Y. Sublingual administration of Lactobacillus paracasei KW3110 inhibits Th2-dependent allergic responses via upregulation of PD-L2 on dendritic cells.
Clinical Immunology. 2012; 143 170-179
Inoue H‚ Mashimo Y‚ Funamizu M‚ Yonekura S‚ Shigtoshi H‚ Shimojo N‚ Kohno Y‚ Okamoto Y‚ Hata A‚ Suzuki Y. Association of the MMP9 gene with childhood cedar pollen sensitization and pollinosis.
J Hum Genet on line publication 2012; 1-8
Aoyagi Y‚ Kuroda M‚ Asada S‚ Tanaka S‚ Tanio M‚ Aso M‚ Okamoto Y‚ Nakayama T‚ Saito Y‚ Bujo H. Fibrin glue is a candidate scafford for long-term therapeutic protein expression in spontaneously differentiated adipocytes in vitro.
Experimental Cell Reseach 2012; 318 1090-1112
Uekusa Y‚ Inamine A‚ Yonekura S‚ Horiguchi S‚Fujimura T‚Sakurai D‚ Yamamoto‚Hanazawa T‚Okamoto Y. Immunological parameters with the development of allergics rhinitis:A preliminary prospective study.
Am J Rhinol Alleg. 2012; 26 (2): 92-96
Aoysgi Y‚Kuroda M‚Asada S‚Tanaka S‚Tanio M‚Aso M‚Okamoto Y‚Nakayama T‚Saito Y‚Bujo H. Fibrin glue is a candidate scaffold for long-term therapeutic protein expression in spontaneously differentiated adipocytes vitro.
Experimental Cell Reseach 2012; 318 (1): 1090-1112
Katada K‚ Tomonaga T‚ Satoh M‚ Matsushita K‚ Tonoike Y‚ Kodera Y‚ Hanazawa T‚ Nomura F‚ Okamoto Y. Plectin promotes migration and invasion of cancer cells and is a novel prognostic marker for head and neck squamous cell carcinoma.
J Proteomics 2012; 75 (6): 1803-1815
Yonekura S‚ Okamoto Y‚ Horiguchi S‚ Sakurai D‚ Chazono H‚ Hanazawa T‚ Okawa T‚ Aoki S‚ Konno A. Effects of aging on the natural history of seasonal allergic rhinitis in middle-aged subjects in South chiba‚ Japan.
Int Arch Allergy Immunol. 2012; 157 (1): 73-80
Ayako Inamine‚Daijyu Sakurai‚ Shigetoshi Horiguchi‚ Syu-ji Yonekura‚ Toyoyuki Hanazawa‚ Hiroyuki Hosakawa‚ Asaka Matuura-Suzuki‚Toshinori Nakayama‚ Yoshitaka Okamoto‚ Sublingual administration of Lactobacillus paracasei KW3110 inhibits Th2-dependent allergic responses via upregulation of PD-L2 on dendritic cells.
Clin Immunol. 2012; 143 (2): 170-179
Kawakami K‚ Enokida H‚ Chiyomaru T‚ Tatarano S‚ Yoshino H‚ Kagara I‚ Gotanda T‚ Tachiwada T‚ Nishiyama K‚ Nohata N‚ Seki N‚ Nakagawa M. The functional significance of miR-1 and miR-133a in renal cell carcinoma.
Eur J Cancer. 2012; 48 (6): 827-836
Yoshino H‚ Enokida H‚ Kawakami K‚ Chiyomaru T‚ Tatarano S‚ Hidaka H‚ Yamasaki T‚ Gotanda T‚ Tachiwada T‚ Nohata N‚ Nishiyama K‚ Seki N‚ Nakagawa M. Tumor suppressive microRNA-1 mediated novel apoptosis pathways through direct inhibition of splicing factor arginine/serine-rich 9 (SRSF9/SRp30c) in bladder cancer.
Biochem Biophys Res Commun. 2012; 417 (1): 588-593
Tatarano S‚ Chiyomaru T‚ Kawakami K‚ Enokida H‚ Yoshino H‚ Hidaka H‚ Nohata N‚ Yamasaki T‚ Gotanda T‚ Tachiwada T‚ Seki N‚ Nakagawa M. Novel oncogenic function of mesoderm development candidate 1 (MESDC1) and its regulation by MiR-574-3p in baldder cancer cell lines.
Int J Oncol. 2012; 40 (4): 951-959
Kojima S‚ Chiyomaru T‚ Kawakami K‚ Yoshino H‚ Enokida H‚ Nohata N‚ Fuse M‚ Ichikawa T‚ Naya Y‚ Nakagawa M‚ Seki N. Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer.
Br J Cancer. 2012; 106 (2): 405-413
Moriya Y‚ Nohata N‚ Kinoshita T‚ Mutallip M‚ Okamoto T‚ Yoshida S‚Suzuki M‚ Yoshino I‚ Seki N. Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma.
J Hum Genet. 2012; 57 (1): 38-45
Kinoshita T‚ Nohata N‚ Yoshino H‚ Hanazawa T‚ Kikkawa N‚ Fujimura L‚ Chiyomaru T‚ Kawakami K‚ Enokida H‚ Nakagawa M‚ Okamoto Y‚ Seki N. Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma.
Int J Oncol. 2012; 40 (1): 185-193
Kidoya‚ H.‚ Kunii‚ N.‚ Naito‚ H.‚ Muramatsu‚ T.‚ Okamoto‚ Y.‚ Nakayama‚ T.‚ and Takakura‚ N. The apelin/APJ system induces maturation of the tumor vasculature and improves the efficiency of immune therapy.
Oncogene 2012; in press
Books
Nohata N‚ Hanazawa T‚ Kinoshita T‚ Okamoto Y‚ Seki N. MicroRNAs function as tumor suppressors or oncogenes: Aberrant expression of microRNAs in head and neck squamous cell carcinoma. Auris Nasus Larynx. 2012; in press
International Conferences
Nohata‚ N. Tumor suppressive microRNA-1 and microRNA-133a cluster regulating molecular targets in head and neck squamous cell carcinoma
8th International Conference on Head and Neck Cancer 2012-7-21 Toronto/Canada
Okamoto Y‚ Inamine A‚ Yonekura S Lactic acid bactera as an effective adjuvant with sublingual immunotherapy for allergic rhinitis.
Âè24²óISIAN 2012-6-17 Tolouse/France
Okamoto Y¡¥ Alternatie¡¡Medicine for allerge rhinitis.
The 14th Japan-Korea Joint Meeting of Otorhinolaryngology/Head & Neck Surgey 2012-4-12 Kyoto/Japan
Nohata‚ N. Identification of Novel Tumor Suppressive microRNAs in Head and Neck Squamous Cell Carcinoma.
The 14th Japan-Korea Joint Meeting of Otorhinolaryngology/Head & Neck Surgey 2012-4-12 Kyoto/Japan
Toyoyuki Hanazawa microRNA-874 as a tumor suppressor in maxillary sinus squamous cell carcinoma based on microRNA expression signature
AACR2012 2012-3-31 Chicago/USA
Kinoshita‚ T. Molecular networks regulated by tumor suppressive microRNA-375 in head and neck squamous cell carcinoma
AACR2012 2012-3-31 Chicago/USA
Nohata‚ N. Molecular networks regulated by tumor suppressive microRNA-1 and microRNA-133a in head and neck squamous cell carcinoma
AACR2012 2012-3-31 Chicago/USA
Okamoto Y. Research and development of the new treatment against allergic rhinitis in Japan
Âè43²ó´Ú¹ñÉ¡²Ê³Ø²ñ 2012-3-11 Seoul/Korea
