Research Achievements

Yoshitaka Okamoto

2012 | 2011 | 2010 | 2009 | 2008 |
| Papers| Books| International Conferences |

Papers

Kondo N‚ Nishimuta T‚ Nishima S‚ Morikawa A‚ Aihara Y‚ Akasaka T‚ Akasawa A‚ Adachi Y‚ Arakawa H‚ Ikarashi T‚ Ikebe T‚ Inoue T‚ Iwata T‚ Urisu A‚ Ebisawa M‚ Ohya Y‚ Okada K‚ Odajima H‚ Katsunuma T‚ Kameda M‚ Kurihara K‚ Kohno Y‚ Sakamoto T‚ Shimojo N‚ Suehiro Y‚ Tokuyama K‚ Nambu M‚ Hamasaki Y‚ Fujisawa T‚ Matsui T‚ Matsubara T‚ Mayumi M‚ Mukoyama T‚ Mochizuki H‚ Yamaguchi K‚ Yoshihara S   Japanese pediatric guidelines for the treatment and management of bronchial asthma 2008.
Pediatr Int.  2010;  52   (2):   319-326


Okita K‚ Motohashi S‚ Shinnakasu R‚ Nagato K‚ Yamasaki K‚ Sato Y‚ Kitamura H‚ Hijikata A‚ Yamashita M‚ Shimizu K‚ Fujii S‚ Ohara O‚ Taniguchi M‚ Sakaida I‚ Nakayama T.   A set of genes associated with the interferon-¦Ã response of lung cancer patients undergoing ¦Á-galactosylceramide-pulsed dendritic cell therapy.
Cancer Sci.  2010;  101     2333-2340


Fujimura T‚ Yonekura S‚ Taniguchi Y‚ Horiguchi S‚ Saito A‚ Yasueda H‚ Nakayama T‚ Takemori T‚ Taniguchi M‚ Sakaguchi M‚ Okamoto Y.   The induced regulatory T cell level‚ defined as the proportion of IL-10(+)Foxp3(+) cells among CD25(+)CD4(+) leukocytes‚ is a potential therapeutic biomarker for sublingual immunotherapy: a preliminary report.
Int Arch Allergy Immunol.  2010;  153     378-387


Yonekura S‚ Okamoto Y‚ Sakurai D‚ Horiguchi S‚ Hanazawa T‚ Nakano A‚ Kudou F‚ Nakamaru Y‚ Honda K‚ Hoshioka A‚ Shimojo N‚ Kohno Y.   Sublingual immunotherapy with house dust extract for house dust-mite allergic rhinitis in children.
Allergol Int.  2010;  59     381-388


Muradil M‚ Okamoto Y‚ Yonekura S‚ Chazono H‚ Hisamitsu M‚ Horiguchi S‚ Hanazawa T‚ Takahashi Y‚ Yokota K‚ Okumura S.   Reevaluation of pollen quantitation by an automatic pollen counter.
Allergy Asthma Proc.  2010;  31     422-427


Kikkawa N‚ Hanazawa T‚ Fujimura L‚ Nohata N‚ Suzuki H‚ Chazono H‚ Sakurai D‚ Horiguchi S‚ Okamoto Y‚ Seki N.   miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC).
British Journal of Cancer  2010;  103     877-884


Kobayashi K‚ Tanaka Y‚ Horiguchi S‚ Yamamoto S‚ Nakayama T‚ Sugimoto A‚ Okamoto Y.   The effect of radiotherapy on NKT cells in patients with advanced head and neck cancer.
Cancer Immunol Immunother  2010;  59     1503-1509


Chiyomaru T‚ Enokida H‚ Tatarano S‚ Kawahara K‚ Uchida Y‚ Nishiyama K‚ Fujimura L‚ Kikkawa N‚ Seki N‚ Nakagawa M.   miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer.¡¡
Br J Cancer.  2010;  102   (5):   883-891


Kano M‚ Seki N‚ Kikkawa N‚ Fujimura L‚ Hoshino I‚ Akutsu Y‚ Chiyomaru T‚ Enokida H‚ Nakagawa M‚ Matsubara H.   miR-145‚ miR-133a and miR-133b: Tumor suppressive miRNAs targets FSCN1 in esophageal squamous cell carcinoma
Int J Cancer  2010;  127   (12):   2804-2814


Fujimura T.‚ Yonekura S.‚ Taniguchi Y.‚ Horiguchi S.‚ Saito A.‚ Yasueda H.‚ Nakayama T.‚ Takemori T.‚ Taniguchi M.‚ Sakaguchi M.‚ and Okamoto Y.   The induced regulatory T-cell level‚ defined as the proportion of IL10+Foxp3+ cells among CD25+CD4+ leukocytes‚ is an available therapeutic biomarker for sublingual immunotherapy: A preliminary report.
Int. Arch. Allergy Immunol.  2010;  153   (4):   378-387


Kanari H‚ Kagami S‚ Kashiwakuma D‚ Oya Y‚ Furuta S‚ Ikeda K‚ Suto A‚ Suzuki K‚ Hirose K‚ Watanabe N‚ Okamoto Y‚ Yamamoto S‚ Iwamoto I‚ Nakajima H.   Role of Th2 cells in IgG4-related lacrimal gland enlargement
Int. Arch. Allergy Immunol.  2010;  152   (Suppl 1):   47-53


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Books

Fujimura T‚ and Okamoto Y.   Antigen-specific immunotherapy against allergic rhinitis: the state of the art.   Allergol. Int.  2010;   59     21-31


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International Conferences

Ayako Inamine‚ Shigetoshi Horiguchi‚ Syu-ji Yonekura‚ Toyoyuki Hanazawa‚ Hiroyuki Hosokawa‚ Asaka Matuura-Suzuki‚ Toshinori Nakayama‚ Yoshitaka Okamoto. Sublingual administration of Lactobacillus paracasei KW3110 inhibits Th2-dependent allergic responses via the up-regulation of PD-L2 on dendritic cells. 
The 10th International Symposium on Dendritic Cells 2010-9-26 Lugano/Switzerland


Kazuki Yamasaki‚ Koji Katada‚ Naoko Kikkawa‚ Shuji Yonekura‚ Yoshitaka Okamoto Phase II study of Activated NKT Cells and ¦Á¡¾GalCer-pulsed DCs in Patients with recurrent and operable Head and Neck Carcinoma 
13th KJ Joint Meeting of Otorhinolaryngology Head & Neck Surgery 2010-9-10 Seoul/Korea


Syuji Yonekura‚ Kazuki Yamasaki‚ Koji Katada‚ Naoko Kikkawa‚ Yoshitaka Okamoto Present Situation of Allergic Rhinitis in Japan 
Âè13²ó´ÚÆü¼ªÉ¡°ö¹¢²Ê³Ø²ñ 2010-9-10 Seul/Japan


Ayako Inamine‚ Akemi Sakamoto‚ Nobuya Yoshida‚ Masashi Arima‚ Jun Ikari‚ Masahiko¡¡Hatano‚ Yoshitaka Okamoto and Takeshi Tokuhisa IL-21 is essential for Long-lived Plasma Cell differentiation 
14th International Congress of Immunology 2010-8-22 Kobe/Japan


Ayako Inamine‚ Shigetoshi Horiguchi‚ Syu-ji Yonekura‚ Toyoyuki Hanazawa‚ Hiroyuki Hosokawa‚ Asaka Matuura-Suzuki‚ Toshinori Nakayama‚ Yoshitaka Okamoto. Sublingual administration of Lactobacillus paracasei KW3110 inhibits Th2-dependent allergic responses via the up-regulation of PD-L2 on dendritic cells. 
7th International Symposium on Tonsils and Mucosal Barriers of the Upper Airways 2010-7-7 Asahikawa/Japan


Yoshitaka Okamoto Allergic rhinitis-comparison of the practical guideline for management of allergic rhinitis in Japan with ARIA 
20th Congress of International Japan/North Asia 2010-7-2 Tokyo/Japan


Nijiro Nobata MicroRNA expression signatures in hypopharyngeal squamous cell carcinoma (HSCC) : miR-489 inhibits cell proliferation by targeting PTPN11 
101st American Cancer Society 2010-4-17 Washington DC/USA


Fujikawa A‚ Okamoto Y Nasal submucosal administration of antigen-presenting cells induces effective immunological responses in immunotherapy 
39th meeting of Korean Rhinologic Society 2010-3-14 Daejeon/Korea


Okamoto Y Early intervention for allergic rhinitis 
39th meeting of Korean Rhinologic Society 2010-3-14 Daejeon/Korea


Kikkawa N. MicroRNA expression signature in hypopharyngeal squamous cell carcinoma (HSCC): miR-489 inhibits cell proliferation by targeting PTPN11. 
Cancer genomics‚ epigenetics‚ and the development of novel therapeutics 2010 2010-2-5 Waikoloa/U.S.A.


Yoshitaka Okamoto‚ Akira Fujikawa‚ Ayako Inamine Nasal submucosal administration of antigen-presenting cells indued effective immunological response in cancer immunotherapy 
7th International Symposium on Tonsils and Mucosal Barriers of the Upper Airways 2010-10-7 Asahikawa/Japan


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