Research Achievements

Yoshitaka Okamoto

2012 | 2011 | 2010 | 2009 | 2008 |
| Papers| Books| International Conferences |

Papers

Asada S‚Kuroda M‚Aoyagi Y‚Fukaya Y‚Tanaka S‚Tanio M‚Aso M‚Satoh K‚Okamoto Y‚Nakayama T‚Saito Y‚Bujo H.   Ceiling culture-derived proliferative adipocytes retain high adi@pogenic potential suitable for use as a vehicle for gene transduction therapy.
American Journal Of Physiology.Cell Physiology.  2011;  301   (1):   1522-1563


Horikoshi T‚ Motoori K‚ Ueda T‚ Shimofusa R‚ Hanazawa T‚ Okamoto Y‚ Ito H.   Head and neck MRI of Kimura disease.
Br J Radiol.  2011;  84   (1005):   800-804


Okamoto Y‚ Fujikawa A‚ Kurosaki M‚ Yamasaki K‚ Sakurai D‚ Horiguchi S‚ Nakayama T.   Nasal submucosal administration of antigen-presenting cells induces effective immunological responses in cancer immunotherapy.
Adv Otorhinolaryngol.  2011;  72     149-152


Nohata N‚ Hanazawa T‚ Kikkawa N‚ Sakurai D‚ Fujimura L‚ Chiyomaru T‚ Kawakami K‚ Yoshino H‚ Enokida H‚ Nakagawa M‚ Katayama A‚ Harabuchi Y‚ Okamoto Y‚ Seki N.   Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma.
Br J Cancer.  2011;  105   (6):   833-841


Yoshida‚ N.‚ Kitayama‚ D.‚ Arima‚ M.‚ Sakamoto‚ A.‚ Inamine‚ A.‚ Takano‚ H.‚ Hatano‚ M.‚ Koike‚ T.‚ and Tokuhisa‚ T.   CXCR4 expression on activated B cells is down-regulated by CD63 and IL-21.
J. Immunol.  2011;  186     2800-2808


Matsuda R‚ Enokida H‚ Chiyomaru T‚ Kikkawa N‚ Sugimoto T‚ Kawakami K‚ Tatarano S‚ Yoshino H‚ Toki K‚ Uchida Y‚ Kawahara K‚ Nishiyama K‚ Seki N‚ Nakagawa M.   LY6K is a novel molecular target in bladder cancer on basis of integrate genome-wide profiling.
Br J Cancer  2011;  18;104   (2):   376-386


Nohata N‚Hanazawa T‚Kikkawa N‚Sakurai D‚Sasaki K‚Chiyomaru T‚Kawakami K‚YoshinoH‚Enokida H‚ Nakagawa M‚Okamoto Y and Seki N.   Identification of novel molecular targets regulated by tumor suppressive miR-1/miR-133a in maxillary sinus squamous cell carcinoma.
Int. J. Oncol  2011;  39   (5):   1099-1107


Nohata N‚Hanazawa T‚Kikkawa N‚ Muradil M‚Sakurai D‚Fujimura L‚ Kawakami K‚Chiyomaru T‚Yoshino H‚ Enokida H‚Nakagawa M‚Okamoto Y and Seki N.   Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC).
J. Hum. Genet.  2011;  56   (8):   595-601


Kurosaki M‚ Horiguchi S‚ Yamasaki K‚ Uchida Y‚ Motohashi S‚ Nakayama T‚ Sugimoto A‚ Okamoto Y.   Migration and immunological reaction after the administration of ¦ÁGalCer-pulsed antigen-presenting cells into the submucosa of patients with head and neck cancer.
Cancer Immunol Immunother.  2011;  60   (2):   207-215


Yamasaki K‚ Horiguchi S‚ Kurosaki M‚ Kunii N‚ Nagato K‚ Hanaoka H‚ Shimizu N‚ Ueno N‚ Yamamoto S‚ Taniguchi M‚ Motohashi S‚ Nakayama T‚ Okamoto   Induction of NKT cell-specific immune responses in cancer tissues after NKT cell-targeted adoptive immunotherapy.
Clin Immunol.  2011;  138   (8):   255-265


Hisamitsu M‚ Okamoto Y‚ Chazono H‚ Yonekura S‚ Sakurai D‚ Horiguchi S‚ Hanazawa T‚ Terada N‚ Konno A‚ Matsuno Y‚ Todaka E‚ Mori C   The Influence of Environmental Exposure to Formaldehyde in Nasal Mucosa of Medical Students during Cadaver Dissection.
Allergol Int.  2011;  60   (3):   373-379


Nohata N‚ Sone Y‚ Hanazawa T‚ Fuse M‚ Kikkawa N‚ Yoshino H‚ Chiyomaru T‚ Kawakami K‚ Enokida H‚ Nakagawa M‚ Shozu M‚ Okamoto Y‚ Seki N   miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma.
Oncotarget  2011;  2   (1-2):   29-42


Yonekura S‚ Okamoto Y‚ Yamasaki K‚ Horiguchi S‚ Hanazawa T‚ Matsune S‚ Kurono Y‚ Yamada T‚ Fujieda S‚ Okano M‚ Okubo K.   A randomized‚ double-blind‚ placebo-controlled study of Ten-Cha (Rubus suavissimus) on house dust mite allergic rhinitis.
Auris Nasus Larynx.  2011;  38   (5):   600-607


Mutallip M‚ Nohata N‚ Hanazawa T‚ Kikkawa N‚ Horiguchi S‚ Fujimura L‚ Kawakami K‚ Chiyomaru T‚ Enokida H‚ Nakagawa M‚ Okamoto Y‚ Seki N.   Glutathione S-transferase P1 (GSTP1) suppresses cell apoptosis and its regulation by miR-133¦Á in head and neck squamous cell carcinoma (HNSCC).
Int J Mol Med.  2011;  27   (3):   345-352


Nohata N‚ Hanazawa T‚ Kikkawa N‚ Mutallip M‚ Fujimura L‚ Yoshino H‚ Kawakami K‚ Chiyomaru T‚ Enokida H‚ Nakagawa M‚ Okamoto Y‚ Seki N.   Caveolin-1 mediates tumor cell migration and invasion and its regulation by miR-133a in head and neck squamous cell carcinoma.
Int J Oncol.  2011;  38   (1):   209-217


Fuse M‚ Nohata N‚ Kojima S‚ Sakamoto S‚ Chiyomaru T‚ Kawakami K‚ Enokida H‚ Nakagawa M‚ Naya Y‚ Ichikawa T‚ Seki N.   Restoration of miR-145 expression suppresses cell proliferation‚ migration and invasion in prostate cancer by targeting FSCN1.
International Journal of Oncology  2011;  38   (4):   1093-1101


Fujimura‚ T.‚ Yonekura‚ S.‚ Horiguchi‚ S.‚ Taniguchi‚ Y.‚ Saito‚ A.‚ Yasueda‚ H.‚ Inamine‚ A.‚ Nakayama‚ T.‚ Takemori‚ T.‚ Taniguchi‚ M.‚ Sakaguchi‚ M.‚ and Okamoto‚ Y.   Increase of regulatory T cells and the ratio of specific IgE to total IgE are candidates for response monitoring or prognostic biomarkers in two-year sublingual immunotherapy (SLIT) for Japanese cedar pollinosis.
Clin. Immunol.  2011;  139   (1):   65-74


¢¥PageTop

Books

Motohashi S‚ Okamoto Y‚ Yoshino I‚ Nakayama T.   Anti-tumor immune responses induced by iNKT cell-based immunotherapy for lung cancer and head and neck cancer.   Clinical Immunology  2011;   140     167-176


Okamoto Y‚ Fujikawa A‚ Kurosaki M‚ Yamasaki K‚ Sakurai D‚ Horiguchi S‚ Nakayama T.   Nasal submucosal administration of antigen-presenting cells induces effective immunological responses in cancer immunotherapy.   Recent advances in tonsils and mucosal barriers of upper airways.  2011;       149-152


¢¥PageTop

International Conferences

Hanazawa T. Identification of tumor suppressive microRNAs in maxillary sinus squamous cell carcinoma based on microRNA expression signature 
102st AACR 2011-7-7 Orlando/USA


Kazuki Yamasaki‚ Shinichiro Motohashi‚ Toshinori Nakayama Induction of NKT Cell-Specific Immune Response in Cancer Tissues after NKT Cell-Targeted Adoptive Immunotherapy 
Clinical Immunology Society‚ Annual Meeting 2011-5-19 Chicago/USA


Hanazawa‚ T Tumor suppressive microRNA-1 and -133a regulates multiple oncogenes in maxillary sinus squamous cell carcinoma. 
11th Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery 2011-11-8 Kobe/Japan


Sakurai‚ D. Immunotherapy for Allergic Rhinitis‚ up-to-date findings 
"Kyung Hee Internation Rhinology Symposium " 2011-11-4 Seoul/Korea


Hanazawa‚ T "A clinical analysis of combination therapy of radiation and intra-arterial chemotherapy for stage III and IV maxillary sinus squamous cell carcinoma " 
14th International Rhinologic Society‚ 30th International Symposium Infection and Allergy of the Nose 2011-11-21 Tokyo/Japan


Hanazawa‚ T Carbon Ion Radiotheapy 
14th International Rhinologic Society‚ 30th International Symposium Infection and Allergy of the Nose 2011-11-21 Tokyo/Japan


Nohata N. Tumor suppressive microRNA-1/-133a regulates multiple oncogenes in maxillary sinus squamous cell carcinoma 
16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine 2011-10-6 Rhodes/Greece


¢¥PageTop