- 2025
- 池原 譲、池原 早苗
細胞・組織のナノイメージングを拓くプラズマ反応の利用
月刊「細胞」2025年８月号 ニューサイエンス社, 東京, 2025年7月20日
Shinsuke Akita, Sanae Ikehara, Masahiro Kiuchi, Kota Kokubo, Kazuhiko Azuma, Syouta Ohki, Hiroyuki Matsuyama, Joceline Theda Kadarman, Yohei Hosokawa, Yoshihiro Akimoto, Yosuke Inaba,
Hideki Hanaoka, Nobuyuki Mitsukawa, Kiyoshi Hirahara, Toshinori Nakayama,
Yuzuru Ikehara
Increased expression of the PIEZO2 mechanoreceptor in fibroblasts and endothelial
cells within the lymphatic and vascular vessels of keloids
The Journal of Pathology 31 July 2025 doi:https://doi.org/10.1002/path.6455
Satoko Nakao, Thillaiampalam Sivakumar, Yuko Takakuwa, Hajime Suzuki, Keiichiro
Ohta, Keiko Nakamura, Osamu Tsuha, Yuzuru Ikehara, Sanae Ikehara, Syota Ohki, Mizue Inumaru, Yukiko Higa, Rika Umemiya-Shirafuji, Naoaki Yokoyama
Seasonal activities, morphological characteristics, and veterinary importance
of Haemaphysalis mageshimaensis in Ishigaki and Yonaguni, Okinawa, Japan
Ticks and Tick-borne Diseases 2025 16(1) 102440
doi: 10.1016/j.ttbdis.2025.102440
榊田 創、池原 譲
大気圧プラズマの医療展開、及び準大気圧プラズマによる成膜プロセス
表面技術 特集「大気圧プラズマ表面処理技術の最新動向」Vol.76 No1 (一社)表面技術協会，東京, 2025年1月1日
- 2024
- 池原 早苗、池原 譲
空間オミクス解析で電子顕微鏡解析を行うために
臨床免疫・アレルギー科第82巻第4号 科学評論社, 東京, 2024年10月25日
Emiri Yamamoto, Shinsuke Akita, Sanae Ikehara, Kazuhiko Azuma,Syota Ohki, Yoshihiro Nakano, Shigehito Sakai, Hiroyuki Matsuyama, Takashi Yamaguchi, Hajime Sakakita, Emilio Martines, Nobuyuki Mitsukawa,Yuzuru Ikehara Application and Evaluation of Plasma Generated by Asymmetric Surface Discharge
on the Ceramic Surface to Hemostatic Equipment. Plasma Medicine 2024 Oct18
14(3):23-36 doi:10.1615/PlasmaMed.v14.i3.20
Ami Aoki, Chiaki Iwamura, Masahiro Kiuchi, Kaori Tsuji, Atsushi Sasaki,
Takahisa Hishiya ,Rui Hirasawa, Kota Kokubo, Sachiko Kuriyama, Atsushi
Onodera, Tadanaga Shimada Tetsutaro Nagaoka Satoru Ishikawa Akira Kojima
Haruki Mito Ryota Hase Yasunori Kasahara, Naohide Kuriyama, Sukeyuki Nakamura,
Takashi Urushibara, Satoru Kaneda ,Seiichiro Sakao, Osamu Nishida, Kazuhisa
Takahashi, Motoko Y Kimura, Shinichiro Motohashi, Hidetoshi Igari, Yuzuru Ikehara ,Hiroshi Nakajima, Takuji Suzuki, Hideki Hanaoka, Taka-Aki Nakada, Toshiaki
Kikuchi, Toshinori Nakayama, Koutaro Yokote, Kiyoshi Hirahara
Suppression of Type I Interferon Signaling in Myeloid Cells by Autoantibodies
in Severe COVID-19 Patients.
Journal of clinical immunology 2024 April 44(4):104 doi:10.1007/s10875-024-01708-7
池原 譲
「病理のお医者さんー医学と工学を結び付けた新しい診断方法 」
不思議のひみつ基地 毎日小学生新聞 2024年1月22号 毎日新聞社，東京，2024
- 2023
- Hayato Ota, Hirokazu Sato, Shuji Mizumoto, Ken Wakai, Kei Yoneda, Kazuo Yamamoto, Hayao Nakanishi, Jun-Ichiro Ikeda, Shinichi Sakamoto, Tomohiko Ichikawa,
Shuhei Yamada, Satoru Takahashi, Yuzuru Ikehara, Shoko Nishihara
Switching mechanism from AR to EGFR signaling via 3-O-sulfated heparan
sulfate in castration-resistant prostate cancer
Scientific Reports, 2023 July 18 ;13(1):11618 doi https://doi.org/10.1038/s41598-023-38746-x
Murakami K, Tamura R, Ikehara S, Ota H, Ichimiya T, Matsumoto N, Matsubara H, Nishihara S, Ikehara Y, Yamamoto K.
Construction of mouse cochlin mutants with different GAG-binding specificities
and their use for immunohistochemistry. Biochem J , 2023 Jan. 13 ;480 (1):
41-56
doi :https://doi.org/10.1042/bcj20220339
- 2022
- Hironobu Kobayashi, Motoko Y Kimura, Ichita Hasegawa, Eisuke Suganuma,
Yuzuru Ikehara, Kazuhiko Azuma, Toshihiro Ito, Ryota Ebata, Yosuke Kurashima, Yohei Kawasaki, Yuki Shiko,
Naoki Saito, Hirotaro Iwase, Youngho Lee, Magali Noval Rivas, Moshe Arditi,
Masahiko Zuka, Hiromichi Hamada, Toshinori Nakayama
Increased Myosin light chain 9 expression during Kawasaki disease vasculitis.
Frontiers in immunology, 2022 ;13: 1036672 doi: https://doi.org/10.3389/fimmu.2022.1036672
Hajime Kasai, Jiro Terada, Jun Nagata, Keiko Yamamoto, Shunya Shiohira,
Atsuko Tomikawa, Nao Tamura, Emiri Yamamoto, Yuzuru Ikehara, Takuji Suzuki
A case of thoracic air leak syndrome with pleural parenchymal fibroelastosis
after treatment for hematologic malignancy while awaiting lung transplantation:
Imaging and pathological findings of rapid loss in lung volume. Respiratory
medicine case reports, 2022 ;37: 101630 doi: https://doi.org/10.1016/j.rmcr.2022.101630
Okano M, Hirahara K, Kiuchi M, Onoue M, Iwamura C, Kokubo K, Hishiya T,
Morimoto Y, Ikehara Y, Murakami A, Ebihara N, Nakayama T.
Interleukin-33-activated neuropeptide CGRP-producing memory Th2 cells cooperate
with somatosensory neurons to induce conjunctival itch.
Immunity. 55, December 13, 1-17
doi: 10.1016/j.immuni.2022.09.016.
Wakai K, Azuma K, Iwamura C, Maimaiti M, Mikami K, Yoneda K, Sakamoto S, Ikehara S, Yamaguchi T, Hirahara K, Ichikawa T, Nakayama T, Ikehara Y. The new preparation method for paraffin-embedded samples applying scanning
electron microscopy revealed characteristic features in asthma-induced
mice.
Sci Rep. 2022 May 31;12(1):9046. doi: 10.1038/s41598-022-12666-8.
Clinical and Histological Effects of Partial Blood Flow Impairment in
Vascularized Lymph Node Transfer.
Akita S, Ikehara Y, Arai M, Tokumoto H, Yamaji Y, Azuma K, Kubota Y, Haneishi H, Kimura MY, Mitsukawa N.
J Clin Med. 2022 Jul 13;11(14):4052. doi: 10.3390/jcm11144052.
実験医学別冊 論文図表を読む作法: 牛島俊和，中山敬一／編
第3章 細胞の形態や性質の解析 3. 走査電子顕微鏡、4.透過電子顕微鏡
秋元 義弘、池原 譲 羊土社 2022年06月30日発行
ISBN 978-4-7581-2260-3
https://www.yodosha.co.jp/yodobook/book/9784758122603/
Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced
lung exudative vasculitis and predicts COVID-19 severity Iwamura C, Hirahara
K, Kiuchi M, Ikehara S, Azuma K, Shimada T, Kuriyama S, Ohki S, Yamamoto E, Inaba Y, Shiko Y, Aoki A,
Kokubo K, Hirasawa R, Hishiya T, Tsuji K, Nagaoka T, Ishikawa S, Kojima
A, Mito H, Hase R, Kasahara Y, Kuriyama N, Tsukamoto T, Nakamura S, Urushibara
T, Kaneda S, Sakao S, Tobiume M, Suzuki Y, Tsujiwaki M, Kubo T, Hasegawa
T, Nakase H, Nishida O, Takahashi K, Baba K, Iizumi Y, Okazaki T, Kimura
MY, Yoshino I, Igari H, Nakajima H, Suzuki T, Hanaoka H, Nakada TA, Ikehara Y, Yokote K, Nakayama T.
Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2203437119.
doi: 10.1073/pnas.2203437119. Epub 2022 Jul 27.
https://www.pnas.org/doi/full/10.1073/pnas.2203437119
新型コロナウイルスを、患者組織で直接観察できるようにしております。
詳しくは下記のリンクの[千葉大学プレスリリース]をご参照ください。
「新型コロナウイルス感染症の重症化メカニズムを解明- 新たな重症化予測マーカーの同定 -」
https://www.ho.chiba-u.ac.jp/hosp/item/newsrelease_20220802.pdf
- 2021
- Hideyuki Ogata, Shinsuke Akita, Sanae Ikehara, Kazuhiko Azuma, Takashi Yamaguchi, Maihulan Maimaiti, Yoshiro Maezawa, Yoshitaka Kubota, Koutaro Yokote, Nobuyuki Mitsukawa,
Yuzuru Ikehara
Calcification in Werner syndrome associated with lymphatic vessels aging.
Aging, 2021 Dec. ;13(24):25717-25728 doi: https://doi.org/10.18632/aging.203789
Shinsuke Akita, Kenji Yoshida, Masaaki Omura, Yoshihisa Yamaji, Takafumi
Tezuka, Hideki Tokumoto, Kazuhiko Azuma, Yuzuru Ikehara, Tadashi Yamaguchi, Nobuyuki Mitsukawa
Noninvasive, objective evaluation of lower extremity lymphedema severity
using shear wave elastography: A preliminary study. JPRAS, 2021 Dec. ;74(12):3377-3385
doi: https://doi.org/10.1016/j.bjps.2021.05.013
Maimaiti M, Sakamoto S, Sugiura M, Kanesaka M, Fujimoto A, Matsusaka K,
Xu M, Ando K, Saito S, Wakai K, Imamura Y, Nakayama K, Kanai Y, Kaneda
A, Ikehara Y, Ikeda JI, Anzai N, Ichikawa T.
The heavy chain of 4F2 antigen promote prostate cancer progression via
SKP-2.
Sci Rep. 2021 Jun 1;11(1):11478. doi: 10.1038/s41598-021-90748-9.
Rii J, Sakamoto S, Sugiura M, Kanesaka M, Fujimoto A, Yamada Y, Maimaiti
M, Ando K, Wakai K, Xu M, Imamura Y, Shindo N, Hirota T, Kaneda A, Kanai
Y,IkeharaY, Anzai N, Ichikawa T.
Functional analysis of LAT3 in prostatecancer: Its downstream target and
relationship with androgen receptor.
Cancer Sci. 2021 Sep;112(9):3871-3883. doi: 10.1111/cas.14991. Epub 2021
Jul 8.
Kawashima S, Inozume T, Kawazu M, Ueno T, Nagasaki J, Tanji E, Honobe A,
Ohnuma T, Kawamura T, Umeda Y, Nakamura Y, Kawasaki T, Kiniwa Y, Yamasaki
O, Fukushima S, Ikehara Y, Mano H, Suzuki Y, Nishikawa H, Matsue H, Togashi Y.
TIGIT/CD155 axis mediates resistance to immunotherapy in patients with
melanoma with the inflamed tumor microenvironment.
J Immunother Cancer. 2021 Nov;9(11):e003134. doi: 10.1136/jitc-2021-003134.
Yamato M, Tamura Y, Tanaka H, Ishikawa K, Ikehara Y, Hori H, Kataoka Y.
Brain cell proliferation in adult rats after irradiation with nonequilibrium
atmospheric pressure plasma.
Applied Physics Express 4(6) 2021 DOI:10.35848/1882-0786/ac03c1.
Manato Kanesaka, Shinichi Sakamoto, Yasutaka Yamada, Junryo Rii, Maihulan
Maimaiti, Tomokazu Sazuka, Yusuke Imamura, Akira Komiya, Koichiro Akakura,
Yuzuru Ikehara, Hiroomi Nakatsu, Tomohiko Ichikawa
Revision of CHAARTED and LATITUDE criteria among Japanese de novo metastatic
prostate cancer patients.
Prostate International, DOI: 10.1016/j.prnil.2021.06.001
Sakakita H, Yamada H, Shimizu T, Fujiwara M, Kato S, Kim J, Ikehara S, Shimizu N, and Ikehara Y.
Effects of electric charges on serum protein aggregation induced by a low
temperature atmospheric pressure plasma.
J Phys. D: Appl. Phys.2021 Vol 54(21) 215201.
Yokoyama N, Sivakumar T, Ikehara S, Akimoto Y, Yamaguchi T, Wakai K, Ishikawa K, Hori M, Shimizu, T, Sakakita H, Ikehara Y.
Growth inhibition effect on Trypanosoma brucei gambiense by the oxidative
stress supplied from low-temperature plasma at atmospheric pressure Selected
Topics in Applied Physics (STAP) Articel, Jpn. J. Appl. Phys. 2021. 60(2)
020601
https://iopscience.iop.org/article/10.35848/1347-4065/abd464
【総説】
Sakakita H, Shimizu T, and Ikehara Y
Reviews of low-temperature atmospheric pressure plasma for studying hemostasis
and international standardization.
Selected Topics in Applied Physics (STAP) Review, Jpn. J. Appl. Phys.
Jpn. J. Appl. Phys. 2021. 60 020502 https://iopscience.iop.org/article/10.35848/1347-4065/abd1bb
- 2020
- Pecori F, Akimoto Y, Hanamatsu H, Furukawa J, Shinohara Y, Ikehara Y, Nishihara S.
Mucin-type O-glycosylation controls pluripotency in mouse embryonic stem
cells via Wnt receptor endocytosis.
J. of Cell Sci. 133: jcs245845 2020, doi: 10.1242/jcs.245845
Shimizu T, Yamada H, Fujiwara M, Kato S, Ikehara Y, and Sakakita H.
Dynamics of flow in albumin solution treated by low-temperature atmospheric
pressure helium plasma jet.
American Institute of Physics (AIP) Advances. 10, 125216, 2020, DOI: 10.1063/5.0033307
Ito Y, Inoue E, Matsui Y, Kobuchi S, Moyama C, Amagase K, Yoshimura M, IkeharaY, Nakata S, Nakanishi H.
Cytology-based Detection of Circulating Tumour Cells in Human Pancreatic
Cancer Xenograft Models With KRAS Mutation
Anticancer Res. 2020 Dec;40(12):6781-6789. doi: 10.21873/anticanres.14701.
Akita S, Yamaji Y, Takeuchi N, Wakai K, Azuma K, Nakagawa A, Fujimoto H,
Sangai T, Nagashima T, Mitsukawa N, Ikehara Y.
Detection of Nonpalpable Tiny Axillary Lymph Nodes Surrounded by Adipose
Tissue Using a Near-Infrared Camera.
Lymphat Res Biol. 2020 Feb 12. doi: 10.1089/lrb.2019.0022.
Maimaiti M, Sakamoto S, Yamada Y, Sugiura M, Rii J, Takeuchi N, Imamura
Y, Furihata T, Ando K, Higuchi K, Xu M, Sazuka T, Nakamura K, Kaneda A,
Kanai Y, Kyprianou N, Ikehara Y, Anzai N, Ichikawa T.
Expression of L-type amino acid transporter 1 as a molecular target for
prognostic and therapeutic indicators in bladder carcinoma.
Sci Rep. 2020 Jan 28;10(1):1292. doi: 10.1038/s41598-020-58136-x.
Yamada H, Kato S, Shimizu T, Fujiwara M, Fujiwara Y, Kim J, Ikehara S, Shimizu N, Ikehara Y, and Sakakita H.
Striation phenomena in a low temperature atmospheric pressure neon plasma
jet by optical emission spectroscopy.
Physics of Plasmas 27, 022107, 2020 doi: 10.1063/1.5124122