研究内容
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業績

英語論文(2016~)

 

❖2024

●H. Piao, H. Ishikawa, T. Kobayashi, K. Kitajo, A.Yamaguchi, K. Koga, M. Shozu 

Progesterone improves motor coordination impairments caused by postnatal hypoxic-ischemic brain insult in neonatal male rats
Pediatrics & Neonatology (in press)    DOI:https://doi.org/10.1016/j.pedneo.2024.03.012

●A. Yamaguchi, T. Jitsuishi

Structural connectivity of the precuneus and its relation to resting-state networks.
Neurosci Res. 2023 Dec 30:S0168-0102(23)00221-3. doi: 10.1016/j.neures.2023.12.004. 

❖2023

●T. Jitsuishi, A. Yamaguchi
Characteristic cortico-cortical connection profile of human precuneus revealed by probabilistic tractography. 
Sci Rep 13, 1936 (2023). https://doi.org/10.1038/s41598-023-29251-2 

●Ito C, Makino T, Mutoh T, Kikkawa M, Toshimori K.
The association of ODF4 with AK1 and AK2 in mice is essential for fertility through its contribution to flagellar shape.
Sci Rep. 13:2969.2023 Feb. (doi: 10.1038/s41598-023-28177-z)

●H. Kikuchi, T.Jitsuishi, S. Hirono, A. Yamaguchi, Y. Iwadate
2D and 3D structures of the whole-brain, directly visible from 100-μm slice
7TMRI images
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management 32 (2023) 101755

●T. Mutoh, H. Kikuchi, T. Jitsuishi, K. Kitajo, A. Yamaguchi
Spatiotemporal expression patterns of ZBP1 in the brain of mouse experimental stroke model
J Chem Neuroanat. 2023 Dec:134:102362. doi: 10.1016/j.jchemneu.2023.102362. 

❖2022
●Tatsuya Jitsuishi, Atsushi Yamaguchi
Searching for optimal machine learning model to classify mild cognitive impairment (MCI) subtypes using multimodal MRI data
Sci Rep. 2022 Mar 11;12(1):4284. doi: 10.1038/s41598-022-08231-y

❖2021
●Tatsuya Jitsuishi, Atsushi Yamaguchi
Posterior Precuneus is Highly Connected to Medial Temporal Lobe Revealed by Tractography and White Matter Dissection
Neuroscience. 2021 Jul 1;466:173-185

●Takashi Hozumi, Setsu Sawai, Tatsuya Jitsuishi, Keiko Kitajo, Kazuhide Inage, Yawara Eguchi, Yasuhiro Shiga, Miyako Narita, Sumihisa Orita, Seiji Ohtori, Atsushi Yamaguchi
Gene expression profiling of the spinal cord at the chronic pain phase identified CDKL5 as a candidate gene for neural remodeling
Neurosci Lett. 2021 Apr 1;749:135772.

●Watanabe E, Akamatsu T, Ohmori M, Kato M, Takeuchi N, Ishiwada N, Nishimura R, Hishiki H, Fujimura L, Ito C, Hatano M.
Recombinant thrombomodulin attenuates hyper-inflammation and glycocalyx damage in a murine model of Streptococcus pneumoniae-induced sepsis.
Cytokine.149(1):155723.2022.(doi:10.1016/j.cyto.2021.155723.)

●Saito T, Terajima M, Taga Y, Hayashi F, Oshima S, Kasamatsu A, Okubo Y, Ito C, Toshimori K Sunohara M, Tanzawa H, Uzawa K, Yamauchi M.
Decrease of lysyl hydroxylase 2 activity causes abnormal collagen molecular phenotypes, defective mineralization and compromised mechanical properties of bone.
Bone.:116242.2021.(doi:10.1016/j.cyto.2021.116242)

❖2020
●Tatsuya Jitsuishi, Atsushi Yamaguchi
Identification of a distinct association fiber tract "IPS-FG" to connect the intraparietal sulcus areas and fusiform gyrus by white matter dissection and tractography
Sci Rep. 2020 Sep 23;10(1):15475.

●Atsushi Yamaguchi, Tatsuya Jitsuishi, Takashi Hozumi, Jun Iwanami, Keiko Kitajo, Hiroo Yamaguchi, Yasutake Mori, Masaki Mogi, Setsu Sawai
Temporal expression profiling of DAMPs-related genes revealed the biphasic post-ischemic inflammation in the experimental stroke model
Mol Brain. 2020 Apr 7;13(1):57.

●Tatsuya Jitsuishi, Seiichiro Hirono, Tatsuya Yamamoto, Keiko Kitajo, Yasuo Iwadate, Atsushi Yamaguchi
White matter dissection and structural connectivity of the human vertical occipital fasciculus to link vision-associated brain cortex
Sci Rep. 2020 Jan 21;10(1):820.

●Okitsu Y, Nagano M, Yamagata T, Ito C, Toshimori K, Dohra H, Fujii W, Yogo K. Dlec1 is required for spermatogenesis and male fertility in mice. Sci Rep 10(1): 18883. 2020. (doi: 10.1038/s41598-020-75957-y.)

●Saito M, Tatsumi T, Nakasuji T, Ibayashi M, Harada T, Mutoh T, Ito C, Komiya A, Hiraoka K, Kawai K. Successful pregnancy and delivery achieved following intracytoplasmic sperm injection using teratozoospermic sperm exhibiting marked dysplasia of the fibrous sheath: a case report. Transl Androl Urol. 9(2): 800-806. 2020. (doi: 10.21037/tau.2019.12.14)

●Yamatoya K, Kousaka M, Ito C, Nakata K, Hatano M, Araki Y, Toshimori K. Cleavage of SPACA1 regulates assembly of sperm-egg membrane fusion machinery in mature spermatozoa. Biol Reprod. 102(3):750-757. 2020. (doi: 10.1093/biolre/ioz223.)

❖2019
●Ito C, Akutsu H, Yao R, Yoshida K, Yamatoya K, Mutoh T, Makino T, Aoyama K, Ishikawa H, Kunimoto K, Tsukita S, Noda T, Kikkawa M, Toshimori K. Odf2 haploinsufficiency causes a new type of decapitated and decaudated spermatozoa, Odf2-DDS, in mice. Sci Rep. 9(1): 14249. 2019. (doi: 10.1038/s41598-019-50516-2.)

●Sakai K, Ito C, Wakabayashi M, Kanzaki S, Ito T, Takada S, Toshimori K, Sekita Y, Kimura T. Usp26 mutation in mice leads to defective spermatogenesis depending on genetic background. Sci Rep. 9(1):13757. 2019.(doi: 10.1038/s41598-019-50318-6.)

●Itoh K, Kondoh G, Miyachi H, Sugai M, Kaneko Y, Kitano S, Watanabe H, Maeda R, Imura A, Liu Y, Ito C, Itohara S, Toshimori K, Fujita J. Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo. Sci Signal. 12(574):eaao7232. 2019. (doi: 10.1126/scisignal.aao7232.)

●Kasamatsu A, Uzawa K, Hayashi F, Kita A, Okubo Y, Saito T, Kimura Y, Miyamoto I, Oka N, Shiiba M, Ito C, Toshimori K, Miki T, Yamauchi M, Tanzawa H. Deficiency of lysyl hydroxylase 2 in mice causes systemic endoplasmic reticulum stress leading to early embryonic lethality. Biochem Biophys Res Commun. 512(3): 486-491. 2019. (doi: 10.1016/j.bbrc.2019.03.091.)

❖2018
●Ito C, Yamatoya K, Yoshida K, Fujimura L, Sugiyama H, Tamura Y, Hatano M, Miyado K, Toshimori K. Deletion of Eqtn in mice reduces male fertility and sperm-egg adhesion. Reproduction.156(6): 579-590.2018. (doi: 10.1530/REP-18-0394.)

●Oami T, Watanabe E, Hatano M, Teratake Y, Fujimura L, Sakamoto A, Ito C, Toshimori K, Swanson PE, Oda S. Blocking liver autophagy accelerates apoptosis and mitochondrial injury in hepatocytes and reduces time to mortality in a murine sepsis model. Shock. 50(4): 427-434. 2018. (doi: 10.1097/SHK.0000000000001040)

❖2017
●Kaneko T, Toshimori K, Iida H. Subcellular localization of MS4A13 isoform 2 in mouse spermatozoa. Reproduction. 154(6):843-857. 2017. (doi: 10.1530/REP-17-0477)

●Dong Y, Isono KI, Ohbo K, Endo TA, Ohara O, Maekawa M, Toyama Y, Ito C, Toshimori K, Helin K, Ogonuki N, Inoue K, Ogura A, Yamagata K, Kitabayashi I, Koseki H. EPC1/TIP60-mediated histone acetylation facilitates spermiogenesis in mice. Mol Cell Biol. 37(19)pii: e0082-17 .2017. (doi: 10.1128/MCB.00082-17)

●Iizuka-Hishikawa Y, Hishikawa D, Sasaki J, Takubo K, Goto M, Nagata K, Nakanishi H, Shindou H, Okamura T, Ito C, Toshimori K, Sasaki T, Shimizu T. Lysophosphatidic acid acyltransferase 3 tunes the membrane status of germ cells by incorporating docosahexaenoic acid during spermatogenesis. J Biol Chem. 292(29): 12065-76 .2017. (doi: 10.1074/jbc.M117.791277)

●Oami T, Watanabe E, Hatano M, Sunahara S, Fujimura L, Sakamoto A, Ito C, Toshimori K, Oda S. Suppression of T cell autophagy result in decreased viability and function of T cells through accelerated apoptosis in a murine sepsis model. Crite Care Med. 45(1): e77-e85. 2017. (doi: 10.1097/CCM.0000000000002016)

❖2016
●Maruyama SY, Ito M, Ikami Y, Okitsu Y, Ito C, Toshimori K, Fujii W, Yogo K. A critical role of solute carrier 22a14 in sperm motility and male fertility in mice. Sci Rep. 6:36468. 2016. (doi: 10.1038/strep36468)

●Chen C, Maekawa M, Yamatoya K, Nozaki M, Ito C, Iwanaga T, Toshimori K. Interaction between basigin and monocarboxylate transporter 2 in the mouse testes and spermatozoa. Asian J Androl. 18(4): 600-606. 2016. (doi: 10.4103/1008-682X.157650)

●Sakiko Fujii, Keisuke Takanashi, Keiko Kitajo, Atsushi Yamaguchi
Treatment with a Global Methyltransferase Inhibitor Induces the Intranuclear aggregation of ALS-Linked FUS Mutant In Vitro.
Neurochemical Research 41(4):826-835 (2016)

●Yamaguchi A, Takanashi K
FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription.
Sci. Rep. 6:35195; doi: 10.1038/srep35195(2016)

 

その他の業績 (2022~)

●年森清隆、伊藤千鶴 (柴原浩章編著)

スキルアップARTラボ 第1章生殖補助医療(ART)の必須知識 ③ラボワーク必須知識 9.精子の構造116-120  2022年4月15日発行 中外医学社 東京(ISBN: 978-4-498-16026-2)