Research Achievements

Toshinori Nakayama

2012 | 2011 | 2010 | 2009 | 2008 |
| Papers| Books| International Conferences |

Papers

Endo‚ Y.‚ Iwamura‚ C.‚ Kuwahara‚ M.‚ Suzuki‚ A.‚ Sugaya‚ K.‚ Tumes‚ J. D.‚ Tokoyoda‚ K.‚ Hosokawa‚ H.‚ Yamashita‚ M.‚ and Nakayama‚ T.   Eomesodermin controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3.
Immunity  2011;  35   (5):   733-745


Tsuyusaki‚ J.‚ Kuroda‚ F.‚ Kasuya‚ Y.‚ Ishizaki‚ S.‚ Yamauchi‚ K.‚ Sugimoto‚ H.‚ Kono‚ T.‚ Iwamura‚ C.‚ Nakayama‚ T.‚ and Tatsumi‚ K.   Cigarette smoke-induced pulmonary inflammation is attenuated in CD69-deficient mice.
J.Recept.Sig.Transduct.Res  2011;  31   (6):   434-439


Takahashi‚ K.‚ Hirose‚ K.‚ Kawashima‚ S.‚ Niwa‚ Y.‚ Wakashin‚ H.‚ Iwata‚ A.‚ Tokoyoda‚ K.‚ Renauld‚ J.-C.‚ Iwamoto‚ I.‚ Nakayama‚ T.‚ and Nakajima‚ H.   IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation.
J.Allergy Clin. Immunol.  2011;  128   (5):   1067-1776


Yamauchi‚ K.‚ Kasuya‚ Y.‚ Kuroda‚ F.‚ Tanaka‚ K.‚ Tsuyusaki‚ J.‚ Ishizaki‚ S.‚ Matsunaga‚ H.‚ Iwamura‚ C.‚ Nakayama‚ T.‚ and Tatsumi‚ K.   Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin.
Respir.Res.  2011;  12     131-


Fujii‚ H.‚ Ato‚ M.‚ Takahashi‚ Y.‚ Otake‚ K.‚ Hashimoto‚ S.‚Kaji‚ T.‚ Tsunetsugu-Yokota‚ Y.‚ Fujita‚ M.‚ Adachi‚ A.‚ Nakayama‚ T.‚ Taniguchi‚ M.‚ Koyasu‚ S.‚ and Takemori‚ T.   HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice.
Int.Immunol.  2011;  23   (7):   433-441


Asada‚ S.‚ Kuroda‚ M.‚ Aoyagi‚ Y.‚ Fukaya‚ Y.‚ Tanaka‚ S.‚ Konno‚ S.‚ Tanio‚ M.‚ Aso‚ M.‚ Satoh‚ K.‚ Okamoto‚ Y.‚ Nakayama‚ T.‚ Saito‚ Y.‚ and Bujo‚ H.   Ceiling culture-derived proliferative adipocytes retain high adipogenic potential suitable for use as a vehicle for gene transduction therapy.
Am J Physiol Cell Physiol.  2011;  301   (1):   C181-185


Kitajima‚ M.‚ Ito‚ T.‚ Tumes‚ J. D.‚ Endo‚ Y.‚ Onodera‚ A.‚ Hashimoto‚ K.‚ Motohashi‚ S.‚ Yamashita‚ M.‚ Nishimura‚ T.‚ Ziegler‚ F. S.‚ and Nakayama‚ T.   Memory type 2 helper T cells induce long-lasting anti-tumor immunity by activating natural killer cells.
Cancer Res.  2011;  71   (14):   4790-4798


Horiuchi‚ S.‚ Onodera‚ A.‚ Hosokawa‚ H.‚ Watanabe‚ Y.‚ Tanaka‚ T.‚ Sugano‚ S.‚ Suzuki‚ Y.‚ and Nakayama‚ T.   Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3.
J. Immunol.  2011;  186     6378-6389


Kitajima‚ M.‚ Lee‚ H.-C.‚ Nakayama‚ T.‚ and Ziegler‚ S. F.   TSLP enhances the function of helper type2 cells.
Eur. J. Immunol.  2011;  41     1862-1871


Nagao‚ T.‚ Suzuki‚ K.‚ Utsunomiya‚ K.‚ Matsumura‚ M.‚ Saiga‚ K.‚ Wang‚ P.-C.‚ Minamitani‚ H.‚ Aratani‚ Y.‚ Nakayama‚ T.‚ and Suzuki‚ K.   Direct activation of glomerular endothelial cells by anti-moesin activity of anti-myeloperoxidase antibody.
Nephrol. Dial. Transplant.  2011;  26     2752-2760


Hirasaki‚ Y.‚ Iwamura‚ C.‚ Yamashita‚ M.‚ Ito‚ T.‚ Kitajima‚ M.‚ Shinoda‚ K.‚ Namiki‚ T.‚ Terasawa‚ K.‚ and Nakayama‚ T.   Repressor of GATA negatively regulates murine contact hypersensitivity through the inhibition of type-2 allergic responses.
Clin. Immunol.  2011;  139     267-276


Yamashita‚ J.‚ Iwamura‚ C.‚ Sasaki‚ T.‚ Mitsumori‚ K.‚ Ohshima‚ K.‚ Hada‚ K.‚ Hara‚ N.‚ Takahashi‚ M.‚ Kaneshiro‚ Y.‚ Tanaka‚ H.‚ Kaneko‚ K.‚ and Nakayama‚ T.   ApolipoproteinA-II suppressed concanavalin A-induced hepatitis via the inhibition of CD4 T cell function.
J. Immunol.  2011;  186   (6):   3410-3420


Fujimura‚ T.‚ Yonekura‚ S.‚ Horiguchi‚ S.‚ Taniguchi‚ Y.‚ Saito‚ A.‚ Yasueda‚ H.‚ Inamine‚ A.‚ Nakayama‚ T.‚ Takemori‚ T.‚ Taniguchi‚ M.‚ Sakaguchi‚ M.‚ and Okamoto‚ Y.   Increase of regulatory T cells and the ratio of specific IgE to total IgE are candidates for response monitoring or prognostic biomarkers in two-year sublingual immunotherapy (SLIT) for Japanese cedar pollinosis.
Clin. Immunol.  2011;  139   (1):   65-74


Phung‚ T. T. B.‚ Luong‚ S. T.‚ Kawachi‚ S.‚ Nunoi‚ H.‚ Nguyen‚ L. T.‚ Nakayama‚ T.‚ and Suzuki‚ K.   Key factor cytokines and myeloperoxidase (MPO) in Vietnamese children with acute respiratory distress syndrome and induced avian influenza (H5N1) infection.
J. Infect.  2011;  in press    


Yamasaki‚ K.‚ Horiguchi‚ S.‚ Kurosaki‚ M.‚ Kunii‚ N.‚ Nagato‚ K.‚ Hanaoka‚ H.‚ Shimizu‚ N.‚ Ueno‚ N.‚ Yamamoto‚ S.‚ Taniguchi‚ M.‚ Motohashi‚ S.‚ Nakayama‚ T.‚ and Okamoto‚ Y.   Induction of NKT cell-specific immune responses in cancer tissues after NKT cell-targeted adoptive immunotherapy.
Clin. Immunol.  2011;  138   (3):   255-265


Aoyagi‚ T.‚ Yamamoto‚ N.‚ Hatta‚ M.‚ Tanno‚ D.‚ Miyazato‚ A.‚ Ishii‚ K.‚ Suzuki‚ K.‚ Nakayama‚ T.‚ Taniguchi‚ M.‚ Kunishima‚ H.‚ Hirakata‚ Y.‚ Kaku‚ M.‚ and Kawakami‚ K.   Activation of pulmonary invariant NKT cells leads to exacerbation of acute lung injury caused by LPS through local production of IFN-¦Ã and TNF-¦Á by Gr-1+ monocytes.
Int. Immunol.  2011;  23   (2):   97-108


¢¥PageTop

Books

Taniguchi‚ M.‚ Fujii‚ S.‚ Nakayama‚ T.‚ Motohashi‚ S.‚ Dashtsoodal‚ N.‚ Watarai‚ H.‚ and Harada‚ M.   Introduction: Mechanisms of NKT-Cell-Mediated Adjuvant Activity and Function of iPS-Deprived NKT Cells. Natural killer T cells   Balancing the Regulation of Tumor Immunity.  2011;   1   (14):  


Motohashi S‚ Okamoto Y‚ Yoshino I‚ Nakayama T.   Anti-tumor immune responses induced by iNKT cell-based immunotherapy for lung cancer and head and neck cancer.   Clinical Immunology  2011;   140     167-176


Motohashi‚ S.‚ Okamoto‚ Y.‚ Nakayama‚ T.   Clinical trials of invariant Natural Killer T cell-based immunotherapy for cancer.   Natural Killer T cells: Balancing the Regulation of Tumor Immunity  2011;       185-198


¢¥PageTop

International Conferences

Nakayama T. NKT-Induced Antigen-Specific Memory Th2 Response 
6th International Symposium on CD1 and NKT cells 2011-9-23 Chicago/USA


Nakayama‚ T. Epigenetic regulation of GATA3 expression and its target genes in Th2 cells. 
45th joint Working Conference on Immunology and Viral Diseases‚ 2011-6-20 Stanford‚CA/USA


Nakayama‚ T.‚ and Onodera‚ A. Regulation of memory Th2 cell function and allergic airway inflammation via polycomb and trithorax molecules. 
30th Congress of the European Academy of Allergy and Clinical Immunology‚ 2011 2011-6-15 Istanbul/Turkey


Nakayama‚ T.‚ and Onodera‚ A. Epigenetic control of memory Th2 cell function via Polycomb and Trithorax molecules. 
EUThyme-Rolduc Meeting 2011-5-24 Leeuwenhorst/Netherland


Nakayama‚ T. Epigenetic control of memory Th2 cell function via Polycomb and Trithorax molecules. 
40th Keystone Symposia 2011-2-6 Banff/Canada


Nakayama‚ T. Epigenetic control of memory Th2 cell function via Polycomb and Trithorax molecules. 
Kenneth R. Wilske lecture series in science and medicine 2011-2-11 Seattle/USA


Onodera A.‚ Horiuchi S.‚ Hosokawa H.‚ Watanabe Y.‚ Suzuki Y.‚ and Nakayama T. Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3 
"NCI Symposium on Chromosone Biology" 2011-10-3 Washington/USA


¢¥PageTop