Research Achievements

| 2012 | 2011 | 2010 | 2009 | 2008 |
| Papers| Books| International Conferences |

Papers

Omata T‚ Fujii K‚ Tanabe Y‚ Arai H‚ Motojima T.   ADEM: The time until diagnosis and its subsequent course in children.
J Child Neurol  2012;   in press    

Fujii K‚ Tanabe Y‚ Uchikawa H‚ Omata T‚ Kohno Y.   14-3-3 proteins‚ particularly of the epsilon isoform‚ are detectable in cerebrospinal fluids of cerebellar diseases in children.
Brain Dev  2012;   in press    

Fujii K‚ Suyama M‚ Chiba K‚ Okunushi T‚ Oikawa J‚ Kohno Y.   Acute disseminated encephalomyelitis associated with 2009 H1N1 influenza vaccine.
Pediatr Int  2012;   54     539-541

Suzuki M‚ Hatsuse H‚ Nagao K‚ Takayama Y‚ Kameyama K‚ Kabasawa Y‚ Omura K‚ Yoshida M‚ Fujii K‚ Miyashita T.   Selective haploinsufficiency of longer isoforms of PTCH1 protein can cause nevoid basal cell carcinoma syndrome.
J Hum Genet  2012;   57     422-426

Fujii K‚ Matsuo K‚ Takatani T‚ Uchikawa H‚ Kohno Y.   Multiple cavitations in posterior reversible leukoencephalopathy syndrome associated with hemolytic-uremic syndrome.
Brain Dev  2012;   34     318-321

Tanaka T‚ Sugaya S‚ Kita K‚ Arai M‚ Kanda T‚ Fujii K‚ Imazeki F‚ Sugita K‚ Yokosuka O‚ Suzuki N.   Inhibition of cell viability by human IFN-β is mediated by microRNA-431.
Int J Oncol  2012;   40     1470-1476

Takahashi Y‚　Fujii K‚ Yoshida A‚ Morisaki H‚ Kohno Y‚ Morisaki T.   Artery Tortuosity Syndrome Exhibiting Early-onset Emphysema with Novel Compound Heterozygous SLC2A10 Mutations
American Journal of Medical Genetics  2012;   in press    

Tanaka J‚ Ishiwada N‚ Wada A‚ Chang B‚ Hishiki H‚ Kurosaki T‚ Kohno Y.   Incidence of childhood pneumonia and serotype and sequence-type distribution in Streptococcus pneumoniae isolates in Japan.
Epidemiol Infect.  2012;   140   (6):   1111-1121

Ishiwada N‚ Takada N‚ Okunushi T‚ Hishiki H‚ Katano H‚ Nakajima N‚ Kohno Y.   Rhabdomyolysis associated with influenza A/H1N1 2009 infection in a pediatric patient.
Pediatr Int.  2012;   54   (5):   703-705

Koga S‚ Ishiwada N‚ Honda（Takahashi) Y‚ Okunushi T‚ Hishiki H‚ Ouchi K‚ Kohno Y.   A case of meningoencephalitis associated with macrolide-resistant Mycoplasma pneumoniae infection.
Pediatr Int.  2012;   54   (5):   724-726

Usui‚ A.‚ Akutsu‚ Y.‚ Kano‚ M.‚ Shuto‚ K.‚ Sakata‚ H.‚ Yoneyama‚ Y.‚ Ikeda‚ N.‚ Oide‚ T.‚ Matsubara‚ H.   Diffusely infiltrative squamous cell carcinoma of the esophagus presenting diagnostic difficulty: report of a case.
Surg Today.  2012;   in press    

Akanuma‚ N.‚ Hoshino‚ I.‚ Akutsu‚ Y.‚ Shuto‚ K.‚ Shiratori‚ T.‚ Kono‚ T.‚ Uesato‚ M.‚ Sato‚ A.‚ Isozaki‚ Y.‚ Maruyama‚ T.‚ Takeshita‚ N.‚ Matsubara‚ H.   Primary esophageal adenocarcinoma arising from heterotopic gastric mucosa: report of a case.
Surg Today.  2012;   in press    

Hoshino‚ I.‚ Matsubara‚ H.   MicroRNAs in cancer diagnosis and therapy: from bench to bedside.
Surg Today.  2012;   in press    

Suganami‚ A.‚ Toyota‚ T.‚ Okazaki‚ S.‚ Saito‚ K.‚ Miyamoto‚ K.‚ Akutsu‚ Y.‚ Kawahira‚ H.‚ Aoki‚ A.‚ Muraki‚ Y.‚ Madono‚ T.‚ Hayashi‚ H.‚ Matsubara‚ H.‚ Omatsu‚ T.‚ Shirasawa‚ H.‚ Tamura‚ Y.   Preparation and characterization of phospholipid-conjugated indocyanine green as a near-infrared probe.
Bioorg Med Chem Lett.  2012;   in press    

Kajiwara‚ T.‚ Matsushita‚ K.‚ Itoga‚ S.‚ Tamura‚ M.‚ Tanaka‚ N.‚ Tomonaga‚ T.‚ Matsubara‚ H.‚ Shimada‚ H.‚ Habara‚ Y.‚ Matsuo‚ M.‚ Nomura‚ F.   SAP155-mediated c-myc suppressor FBP-interacting repressor splicing variants are activated in colon cancer tissues.
Cancer Sci.  2012;   in press    

Akutsu‚ Y.‚ Uesato‚ M.‚ Shuto‚ K.‚ Kono‚ T.‚ Hoshino‚ I.‚ Horibe‚ D.‚ Sazuka‚ T.‚ Takeshita‚ N.‚ Maruyama‚ T.‚ Isozaki‚ Y.‚ Akanuma‚ N.‚ Matsubara‚ H.   The Overall Prevalence of Metastasis in T1 Esophageal Squamous Cell Carcinoma: A Retrospective Analysis of 295 Patients.
Ann Surg.  2012;   in press    

Akutsu‚ Y.‚ Shuto‚ K.‚ Kono‚ T.‚ Uesato‚ M.‚ Hoshino‚ I.‚ Shiratori‚ T.‚ Miyazawa‚ Y.‚ Isozaki‚ Y.‚ Akanuma‚ N.‚ Matsubara H.   A Phase I/II Study of Second-Line Chemotherapy with Fractionated Docetaxel and Nedaplatin for 5-FU/Cisplatin-Resistant Esophageal Squamous Cell Carcinoma.
Hepatogastroenterology.  2012;   59   (119):  

Hayano‚ K.‚ Miura‚ F.‚ Amano‚ H.‚ Toyota‚ N.‚ Wada‚ K.‚ Kato‚ K.‚ Sano‚ K.‚ Takeshita‚ K.‚ Aoyagi‚ T.‚ Shuto‚ K.‚ Matsubara‚ H.‚ Asano‚ T.‚ Takada‚ T.   Correlation of apparent diffusion coefficient measured by diffusion-weighted MRI and clinicopathologic features in pancreatic cancer patients.
J Hepatobiliary Pancreat Sci.  2012;   in press    

Sobirin MA‚ Kinugawa S‚ Takahashi M‚ Fukushima A‚ Homma T‚ Ono T‚ Hirabayashi K‚ Suga T‚ Azalia P‚ Takada S‚ Taniguchi M‚ Nakayama T‚ Ishimori N‚ Iwabuchi K‚ Tsutsui H.   Activation of natural killer T cells ameliorates postinfarct cardiac remodeling and failure in mice.
Circ Res.  2012;   111   (8):   1037-1047

Yamada Y‚ Sawai S‚ Misawa S‚ Kanai K‚ Shibuya K‚ Mori M‚ Moriya J‚ Sogawa K‚ Yamamoto H‚ Beppu M‚ Taniguchi J‚ Nakaseko C‚ Nomura F‚ Kuwabara S   Multiple angiogenetic factors are upregulated in POEMS syndrome
Ann Hematol  2012;   in press    

Oshima K‚ Kanda Y‚ Nanya Y‚ Tanaka M‚ Nakaseko C‚ Yano S‚ Fujisawa S‚ Fujita H‚ Yokota A‚ Takahashi S‚ Kanamori H‚ Okamoto S for the Kanto Study Group for Cell Therapy (KSGCT)   Allogeneic hematopoietic stem cell transplantation for patients with mildly reduced renal function as defined based on creatinine clearance before transplantation
Ann Hematol  2012;   in press    

Kitazono-Saitoh M‚ Takiguchi Y‚ Kitazono S‚ Ashinuma H‚ Kitamura A‚ Tada Y‚ Kurosu K‚ Sakaida E‚ Sekine I‚ Tanabe N‚ Tagawa M‚ Tatsumi K   Interaction and cross-resistance of cisplatin and pemetrexed in malignant pleural mesothelioma cell lines.
Oncol Rep  2012;   28   (1):   33-40

Ashinuma H‚ Takiguchi Y‚ Kitazono S‚ Kitazono-Saitoh M‚ Kitamura A‚ Chiba T‚ Tada Y‚ Kurosu K‚ Sakaida E‚ Sekine I‚ Tanabe N‚ Iwama A‚ Yokosuka O‚ Tatsumi K   Antiproliferative action of metformin in human lung cancer cell lines
Oncol Rep  2012;   28   (1):   8-14

Fuse M‚ Kojima S‚ Enokida H‚ Chiyomaru T‚ Yoshino H‚ Nohata N‚ Kinoshita T‚ Sakamoto S‚ Naya Y‚ Nakagawa M‚ Ichikawa T‚ Seki N.   Tumor suppressive microRNAs (miR-222 and miR-31) regulate molecular pathways based on microRNA expression signature in prostate cancer.
J Hum Genet.  2012;   in press    

Kinoshita T‚ Hanazawa T‚ Nohata N‚ Okamoto Y‚ Seki N.   The functional significance of microRNA-375 in human squamous cell carcinoma: aberrant expression and effects on cancer pathways.
J Hum Genet.  2012;   57   (9):   556-563

Endoh M‚ Endo TA‚ Endoh T‚ Isono K‚ Sharif J‚ Ohara O‚ Toyoda T‚ Ito T‚ Eskeland R‚ Bickmore WA‚ Vidal M‚ Bernstein BE‚ Koseki H.   Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity.
PLoS Genet.  2012;   8   (7):   e1002774-

Hori T‚ Ohnishi H‚ Teramoto T‚ Tsubouchi K‚ Naiki T‚ Hirose Y‚ Ohara O‚ Seishima M‚ Kaneko H‚ Fukao T‚ Kondo N.   Autosomal-Dominant Chronic Mucocutaneous Candidiasis with STAT1-Mutation can be Complicated with Chronic Active Hepatitis and Hypothyroidism.
J Clin Immunol  2012;   in press    

Kaji T‚ Ishige A‚ Hikida M‚ Taka J‚ Hijikata A‚ Kubo M‚ Nagashima T‚ Takahashi Y‚ Kurosaki T‚ Okada M‚ Ohara O‚ Rajewsky K‚ Takemori T.   Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
J Exp Med.  2012;   in press    

Shigeta A‚ Tada Y‚ Wang J.Y‚ Ishizaki S‚ Tsuyusaki J‚ Yamauchi K‚ Kasahara Y‚ Iesato K‚ Tanabe N‚ Takiguchi Y‚ Sakamoto A‚ Tokuhisa T‚ Shibuya K‚ Hiroshima K‚ West J‚ Tatsumi K.   CD40 amplifies Fas-mediated apoptosis: a mechanism contributing to emphysema.
Am J Physiol Lung Cell Mol Physiol.  2012;   303     141-151

Tsutsuki H‚ Yahiro K‚ Suzuki K‚ Suto A‚ Ogura K‚ Nagasawa S‚ Ihara H‚ Shimizu T‚ Nakajima H‚ Moss J‚ Noda M.   Subtilase cytotoxin suppresses nitric oxide production by macrophages through inhibition of NF-κB activation.
Infec Immun.  2012;   80     3939-3951

Nakagomi D‚ Suzuki K‚ Hosokawa J‚ Kobayashi T‚ Suto A‚ Takatori H‚ Watanabe N‚ Matsue H‚ Shimada S‚ Nakajima H.   B and T lymphocyte attenuator expressed on CD8+ T cells inhibits contact hypersensitivity reaction.
J Invest Dermatol.  2012;   in press    

Kawashima S‚ Hirose K‚ Iwata A‚ Takahashi T‚ Ohkubo A‚ Tamachi T‚ Ikeda K Kagami S‚ Nakajima H.   β-glucan curdlan induces IL-10-producing CD4+ T cells and inhibits allergic airway inflammation.
J Immunol  2012;   in press    

Iwamura C‚ Shinoda K‚ Endo Y‚ Watanabe Y‚ Tumes D.J‚ Motohashi S‚ Kawahara K‚ Kinjo Y‚ Nakayama T.   Regulation od memory CD4 T-cell pool size and function by natural killer T cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America.  2012;   109   (42):   16992-16997

Tanaka T‚ Takahashi K‚ Yamane M‚ Tomida S‚ Nakamura S‚ Oshima K‚ Niwa A‚ Nishikomori R‚ Kambe N‚ Hara H‚ Mitsuyama M‚ Morone N‚ Heuser JE‚ Yamamoto T‚ Watanabe A‚ Sato-Otsubo A‚ Ogawa S‚ Asaka I‚ Heike T‚ Yamanaka S‚ Nakahata T‚ Saito MK.   Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery.
Blood.  2012;   120     1299-1308

Nakamura Y‚ Franchi L‚ Kambe N‚ Meng G‚ Strober W‚ Núñez G   Critical role for mast cells in interleukin-1β-driven skin inflammation associated with an activating mutation in the Nlrp3protein.
Immunity.  2012;   37     85-95

Kono‚ K.‚ Iinuma‚ H.‚ Akutsu‚ Y.‚ Tanaka‚ H.‚ Hayashi‚ N.‚ Uchikado‚ Y.‚ Noguchi‚ T.‚ Fujii‚ H.‚ Okinaka‚ K.‚ Fukushima‚ R.‚ Matsubara‚ H.‚ Ohira‚ M.‚ Baba‚ H.‚ Natsugoe‚ S.‚ Kitano‚ S.‚ Takeda‚ K.‚ Yoshida‚ K.‚ Tsunoda‚ T.‚ Nakamura Y.   Multicenter‚ phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens.
J Transl Med.  2012;   10   (1):   141-

Isozaki‚ Y.‚ Hoshino‚ I.‚ Nohata‚ N.‚ Kinoshita‚ T.‚ Akutsu‚ Y.‚ Hanari‚ N.‚ Mori‚ M.‚ Yoneyama‚ Y.‚ Akanuma‚ N.‚ Takeshita‚ N.‚ Maruyama‚ T.‚ Seki‚ N.‚ Nishino‚ N.‚ Yoshida‚ M.‚ Matsubara‚ H.   Identification of novel molecular targets regulated by tumor suppressive miR-375 induced by histone acetylation in esophageal squamous cell carcinoma.
Int J Oncol.  2012;   41   (3):   985-994

Miura‚ F.‚ Sano‚ K.‚ Amano‚ H.‚ Watanabe‚ T.‚ Takada‚ T.‚ Matsubara‚ H.   Gallbladder cancer involving the extrahepatic bile duct.
Ann Surg.  2012;   255   (6):   e20-

Matsushita‚ K.‚ Kajiwara‚ T.‚ Tamura‚ M.‚ Satoh‚ M.‚ Tanaka‚ N.‚ Tomonaga‚ T.‚ Matsubara‚ H.‚ Shimada‚ H.‚ Yoshimoto‚ R.‚ Ito‚ A.‚ Kubo‚ S.‚ Natsume‚ T.‚ Levens‚ D.‚ Yoshida‚ M.‚ Nomura‚ F.   SAP155-Mediated Splicing of FUSE-Binding Protein-Interacting Repressor Serves as a Molecular Switch for c-myc Gene Expression.
Mol Cancer Res.  2012;   10   (6):   787-799

Obul‚ J.‚ Itoga‚ S.‚ Abliz‚ M.‚ Sato‚ K.‚ Ishige‚ T.‚ Utsuno‚ E.‚ Matsushita‚ K.‚ Matsubara‚ H.‚ Nomura‚ F.   High-resolution melting analyses for gene scanning of APC‚ MLH1‚ MSH2‚ and MSH6 associated with hereditary colorectal cancer.
Genet Test Mol Biomarkers.  2012;   16   (5):   406-411

Aoyagi‚ T.‚ Shuto‚ K.‚ Okazumi‚ S.‚ Hayano‚ K.‚ Satoh‚ A.‚ Saitoh‚ H.‚ Shimada‚ H.‚ Nabeya‚ Y.‚ Kazama‚ T.‚ Matsubara‚ H.   Apparent diffusion coefficient correlation with oesophageal tumour stroma and angiogenesis.
Eur Radiol.  2012;   22   (6):   1172-1177

Akutsu‚ Y.‚ Shuto‚ K.‚ Kono‚ T.‚ Uesato‚ M.‚ Hoshino‚ I.‚ Shiratori‚ T.‚ Isozaki‚ Y.‚ Akanuma‚ N.‚ Uno‚ T.‚ Matsubara‚ H.   The number of pathologic lymph nodes involved is still a significant prognostic factor even after neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma.
J Surg Oncol.  2012;   105   (8):   756-760

Usui‚ A.‚ Hoshino‚ I.‚ Akutsu‚ Y.‚ Sakata‚ H.‚ Nishimori‚ T.‚ Murakami‚ K.‚ Kano‚ M.‚ Shuto‚ K.‚ Matsubara‚ H.   The molecular role of Fra-1 and its prognostic significance in human esophageal squamous cell carcinoma. Cancer.
Cancer.  2012;   118   (13):   3387-3396

Akutsu‚ Y.‚ Yasuda‚ S.‚ Nagata‚ M.‚ Izumi‚ Y.‚ Okazumi‚ S.‚ Shimada‚ H.‚ Nakatani‚ Y.‚ Tsujii‚ H.‚ Kamada‚ T.‚ Yamada‚ S.‚ Matsubara‚ H.   A phase I/II clinical trial of preoperative short-course carbon-ion radiotherapy for patients with squamous cell carcinoma of the esophagus.
J Surg Oncol.  2012;   105   (8):   750-755

Kawahira‚ H.‚ Hayashi‚ H.‚ Natsume‚ T.‚ Akai‚ T.‚ Uesato‚ M.‚ Horibe‚ D.‚ Mori‚ M.‚ Hanari‚ N.‚ Aoyama‚ H.‚ Nabeya‚ Y.‚ Shuto‚ K.‚ Matsubara‚ H.   Surgical Advantages of Gastric SMTs by Laparoscopy and Endoscopy Cooperative Surgery.
Hepatogastroenterology.  2012;   59   (114):   415-417

Shunichiro Onishi‚ Minoru Takemoto‚ Emiko Okabe‚ Takahiro Ishikawa‚ Ryouichi Ihibashi‚ Peng He‚ Kazuki Kobayashi‚ Masaki Fujimoto‚ Harukiyo Kawamura‚ Koutaro Yokote   Japanese diabetic patients with Werner syndrome exhibit high incidence of cancer.
Acta Diabetologica  2012;   in press    

Okabe E‚ Takemoto M‚ Onishi S‚ Ishikawa T‚ Ishibashi R‚ He P‚ Kobayashi K‚ Fujimoto M‚ Kawamura H‚ Yokote K. J   Incidence and characteristics of metabolic disorders and vascular complications in individuals with Werner syndrome in Japan.
J Am Geriatr Soc  2012;   60     997-998

Onishi S‚ Takemoto M‚ Ishikawa T‚ Okabe E‚ RIshibashi R‚ He P‚ Kobayashi K‚ Fujimoto M‚ Kawamura H‚ Yokote K‚   Japanese diabetic patients with Werner syndrome exhibit high incidence of cancer
Acta Diabetologica  2012;   in press    

Mezawa M‚ Takemoto M‚ Onishi S‚ Ishibashi R‚ Ishikawa T‚ Yamaga M‚ Fujimoto M‚ Okabe E‚ He P‚ Kobayashi K‚ Yokote K   The reduced form of coenzyme Q10 improves glycemic control in patients with type 2 diabetes.
BioFactors  2012;   in press    

Kitamoto　T‚ Takemoto M ‚ Fujimoto M‚ Ishikawa T‚ Onishi S‚ Okabe E‚ Ishibashi R‚ Kobayashi K‚ Kawamura H‚ Yokote K   Sitagliptin successfully ameliorates glycemic control in a Werner’s syndrome with diabetes mellitus.
Diabetes Care  2012;   in press    

Tsuyoshi Matsumoto‚ Kenichi Sakurai‚ Asami Tanaka‚ Takayuki Ishibashi‚ Kaori Tachibana‚ Ko Ishikawa‚ Koutaro Yokote.   The anti-ulcer agent‚ irsogladine‚ increases insulin secretion by MIN6 cells
European Journal of Pharmacology  2012;   685     213-217

Mariko Harada-Shiba‚ Hidenori Arai‚ Shinichi Oikawa‚ Takao Ohta‚ Tomoo Okada‚ Tomonori Okamura‚ Atsushi Nohara‚ Hideaki Bujo‚ Koutaro Yokote‚ Akihiko Wakatsuki‚ Shun Ishibashi‚ Shizuya Ya‚ashita   Guidelines for the Management of Familial Hypercholesterolemia
J Atheroscler Thromb  2012;   in press    

Sakai S‚ Nakaseko C‚ Takeuchi M‚ Ohwada C‚ Shimizu N‚ Tsukamoto S‚ Kawaguchi T‚ Jiang M‚ Sato Y‚ Ebinuma H‚ Yokote K‚ Iwama A‚ Fukamachi I‚ Schneider WJ‚ Saito Y‚ Bujo H   Circulating soluble LR11/SorLA levels are highly increased and ameliorated by chemotherapy in acute leukemias
Clinica Chimica Acta  2012;   in press    

Shimizu N‚ Sakaida E‚ Ohwada C‚ Takeuchi M‚ Kawaguchi T‚ Tsukamoto S‚ Sakai S‚ Takeda Y‚ Sugita Y‚ Yokote K‚ Iseki T‚ Isose S‚ Kanai K‚ Misawa S‚ Kuwabara S‚ Nakaseko C   Mobilization of peripheral blood stem cells in poor mobilizers with POEMS syndrome using G-CSF with plerixafor
Bone Marrow Transplant  2012;      

Shimizu N‚ Nakaseko C‚ Sakaida E‚ Ohwada C‚ Takeuchi M‚ Tanaka S‚ Muto T‚ Kawaguchi T‚ Tsukamoto S‚ Sakai S‚ Takeda Y‚ Abe D‚ Yokote K‚ Iseki T‚ Kanai K‚ Misawa S‚ Kuwabara S   Factors associated with the efficiency of peripheral blood stem cell harvest in patients with POEMS syndrome undergoing autologous peripheral blood stem cell transplantation
Bone Marrow Transplant  2012;      

Kanai K‚ Sawai S‚ Sogawa K‚ Mori M‚ Misawa S‚ Shibuya K‚ Isose S‚ Fujimaki Y‚ Sekiguchi Y‚ Nasu S‚ Nakaseko C‚ Takano S‚ Yoshitomi H‚ Miyazaki M‚ Nomura F‚ Kuwabara S (*equally contributed to the study)   Markedly upregulated interleukin-12 as a novel biomarker in POEMS syndrome
Neurology  2012;   in press    

Takeuchi M‚ Nakaseko C‚ Ohwada C‚ Sato Y‚ Ohashi K‚ Kakihana K‚ Mori T‚ Aisa Y‚ Kanda Y‚ Takahashi S‚ Yokota A‚ Kawaguchi T‚ Saitoh T‚ Hatsumi N‚ Taguchi J‚ Takasaki H‚ Kanamori H‚ Maruta A‚ Sakamaki H‚ and Okamoto S   Allogeneic hematopoietic stem cell transplantation for primary and secondary myelofibrosis: a retrospective‚ multicenter study of the Kanto Study Group for Cell Therapy (KSGCT)
J Hematopoietic Cell Transplant  2012;   in press    

Ohnishi K‚ Nakaseko C‚ Takeuchi J‚ Fujisawa S‚ Nagai T‚ Yamazaki H‚ Tauchi T‚ Imai K‚ Mori N‚ Yagasaki F‚ Akiyama H‚ Maeda Y‚ Usui N‚ Saburi Y‚ Ishida T‚ Kosugi H‚ Miyamura K‚ Miyazaki Y‚ Handa H‚ Yokota A‚ Matsumoto K‚ Fujimaki K‚ Matsui T‚ Kiyoi H‚ Miyawaki S‚ Ohtake S‚ Ohno R‚ Naoe T   Excellent long-term outcomes of imatinib therapy in newly diagnosed Japanese patients with chronic myelogenous leukemia in chronic phase: Analysis of the mean daily doses and blood levels of imatinib in the JALSG CML202 study
Cancer Sci  2012;   103   (6):   1071-1078

Usuki K‚ Tojo A‚ Maeda Y‚ Kobayashi Y‚ Matsuda A‚ Ohyashiki K‚ Nakaseko C‚ Kawaguchi T‚ Tanaka H‚ Miyamura K‚ Miyazaki Y‚ Okamoto S‚ Oritani K‚ Okada M‚ Usui N‚ Nagai T‚ Amagasaki T‚ Wanajo A‚ Naoe T   Efficacy and safety of nilotinib in Japanese patients with imatinib-resistant or -intolerant Ph+ CML or relapsed/refractory Ph+ ALL: a 36-month analysis of a phase I and II study
Int J Hematol  2012;   95   (4):   409-419

Tsukamoto S‚ Takeuchi M‚ Kawajiri C‚ Tanaka S‚ Nagao Y‚ Sugita Y‚ Yamazaki A‚ Kawaguchi T‚ Muto T‚ Sakai S‚ Takeda Y‚ Ohwada C‚ Sakaida E‚ Shimizu N‚ Yokote K‚ Iseki T‚ Nakaseko C   Posterior reversible encephalopathy syndrome in an adult patient with acute lymphoblastic leukemia after remission induction chemotherapy.
Int J Hematol  2012;   95   (2):   204-208

Yokota A‚ Ozawa S‚ Tsuji M‚ Akiyama H‚ Ohshima K‚ Kanda Y‚ Takahashi S‚ Mori T‚ Nakaseko C‚ Onoda M‚ Kishi K‚ Doki N‚ Aotsuka N‚ Kanamori H‚ MarutaA‚ Sakamaki H‚ Okamoto S   Secondary solid tumors aftger allogeeic stem cell transplantation in Japan
Bone Marrow Transplant  2012;   47   (1):   95-100

Ma H‚ Gong H‚ Chen Z‚ Liang Y‚ Yuan J‚ Zhang G‚ Wu J‚ Ye Y‚ Yang C‚ Nakai A‚ Komuro I‚ Ge J‚ Zou Y.   Association of Stat3 with HSF1 plays a critical role in G-CSF-induced cardio-protection against ischemia/reperfusion injury.
J Mol Cell Cardiol  2012;      

Iwashita M‚ Sakoda H‚ Kushiyama A‚ Fujishiro M‚ Ohno H‚ Nakatsu Y‚ Fukushima T‚ Kumamoto S‚ Tsuchiya Y‚ Kikuchi T‚ Kurihara H‚ Akazawa H‚ Komuro I‚ Kamata H‚ Nishimura F‚ Asano T.   Valsartan‚ independently of AT1 receptor or PPARγ‚ suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.
Am J Physiol Endocrinol Metab  2012;   302     E286-296

Fukushima N‚ Matsuura K‚ Akazawa H‚ Honda A‚ Nagai T‚ Takahashi T‚ Seki A‚ Murasaki KM‚ Shimizu T‚ Okano T‚ Hagiwara N‚ Komuro I.   A crucial role of activin A-mediated growth hormone suppression in mouse and human heart failure.
PLoS One  2012;   6e27901    

Yasuda N‚ Akazawa H‚ Ito K‚ Shimizu I‚ Kudo-Sakamoto Y‚ Yabumoto C‚ Yano M‚ Yamamoto R‚ Ozasa Y‚ Minamino T‚ Naito AT‚ Oka T‚ Shiojima I‚ Tamura K‚ Umemura S‚ Nemer M‚ Komuro I.   Agonist-Independent Constitutive Activity of Angiotensin II Receptor Promotes Cardiac Remodeling in Mice.
Hypertension  2012;      

Sakata Y‚ Nakatani D‚ Shimizu M‚ Suna S‚ Usami M‚ Matsumoto S‚ Hara M‚ Sumitsuji S‚ Kawano S‚ Iwakura K‚ Hamasaki T‚ Sato H‚ Nanto S‚ Hori M‚ Komuro I.   Oral treatment with nicorandil at discharge is associated with reduced mortality after acute myocardial infarction.
J Cardiol  2012;   59     14-21

Shinichiro Mori‚ Kouichi Shibayama‚ Katsuyuki Tanimoto‚ Motoki Kumagai‚ Yuka Matsuzaki‚ Takuji Furukawa‚ Taku Inaniwa‚ Toshiyuki Shirai‚ Kouji Noda‚ Hiroshi Tsuji‚ Tadashi Kamada   First clinical experience in carbon-ion scanning beam therapy: retrospective analysis of patient positional accuracy
Journal of Radiation Research  2012;      

Hitoshi Ishikawa*‚ Hiroshi Tsuji‚ Tadashi Kamada‚ Kouichirou Akakura‚ Hiroyosi Suzuki‚ Jun Shimazaki‚ Hirohiko Tsujii   Carbon-ion radiation therapy for prostate cancer
International Journal of Urology  2012;      

Junetsu Mizoe‚ Azusa Hasegawa‚ Keiichi Jingu‚ Ryo Takagi‚ Hiroki Bessho‚ Takamichi Morikawa‚ Morio Tonogi‚ Hiroshi Tsuji‚ Tadashi Kamada‚ Hirohiko Tsujii‚ Yoshitaka Okamoto   Results of carbon ion radiotherapy for head and neck cacer‚
Radiotherapy and Oncology  2012;   103   (1):   32-37

Tadashi Kamada   Clinical evidence of particle beam therapy (carbon)
International Journal of Clinical Oncology  2012;   17   (2):   85-88

Jun Shimazaki‚ Hiroshi Tsuji‚ Hitoshi Ishikawa*‚ Tadashi Kamada‚ Masaoki Harada*‚ Kouichirou Akakura‚ Hiroyosi Suzuki‚ Ichikawa Tomohiko‚ Hirohiko Tsujii   Biochemical failure after carbon ion radiotherapy for prostate cancer‚
Anticancer Research  2012;   32   (8):   3267-3274

Sakamoto Y‚ Baba T‚ Kouzu Y‚ Koike H‚ Kasamatsu A‚ Ogawara K‚ Shiiba M‚ Uzawa K‚ Tanzawa H   A case of an epidermoid cyst arising in the maxillary sinus
Journal of Oral and Maxillofacial Surgery‚ Medicine‚ and Pathology  2012;   in press    

Shiiba M‚ Ishige S‚ Saito Y‚ Shimizu T‚ Minakawa Y‚ Kasamatsu A‚ Ogawara K‚ Uzawa K‚ Tanzawa H   Down-regulated expression of family with sequence similarity 3‚ member B (FAM3B)‚ in oral squamous cell carcinoma
Oral Science International  2012;   9   (1):   9-16

Kasamatsu A‚ Shiiba M‚ Nakashima D‚ Shimada K‚ Higo M‚ Ishigami T‚ Ishige S‚ Ogawara K‚ Tanzawa H‚ Uzawa K.   Epithelioid myoepithelioma of the hard palate.
Oral Maxillofac Surg.  2012;   in press    

Kasamatsu A‚ Iyoda M‚ Usukura K‚ Sakamoto Y‚ Ogawara K‚ Shiiba M‚ Tanzawa H‚ Uzawa K.   Gibberellic acid induces α-amylase expression in adipose-derived stem cells.
Int J Mol Med.  2012;   30   (2):   243-247

Sekine‚ S.‚ Mitsuki‚ K.‚ Ito‚ K.‚ Kugioka‚ S.‚ and Horie‚ T.   Sustained intrahepatic glutathione depletion causes proteasomal degradation of multidrug resistance-associated protein 2 in rat liver.
Biochim. Biophys. Acta  2012;   1822   (6):   980-987

Oga‚ E.F.‚ Sekine‚ S‚ Shitara‚ Y‚ and Horie‚ T.   Potential P-glycoprotein-mediated drug-drug interactions of antimalarial agents in Caco-2 cells.
Am. J. Trop. Med. Hyg.  2012;   87   (1):   64-69

Nakano T‚ Shimojo N‚ Okamoto Y‚ Ebisawa M‚ Kurihara K‚ Hoshioka A‚ Yamaguchi K‚ Ito K‚ Fujisawa T‚ Kameda M‚ Suehiro Y‚ Ogura H‚ Shibata R‚ Suzuki S‚ Takahashi Y‚ Ikeda I‚ Kohno Y.   The use of complementary and alternative medicine by pediatric food-allergic patients in Japan.
Int Arch Allergy Immunol  2012;   in press    

Yamaide F‚ Undarmaa S‚ Mashimo Y‚ Shimojo N‚ Arima T‚ Morita Y‚ Hirota T‚ Fujita K‚ Miyatake A‚ Doi S‚ Sato K‚ Suzuki S‚ Nishimuta T‚ Watanabe H‚ Hoshioka A‚ Tomiita M‚ Yamaide A‚ Watanabe M‚ Okamoto Y‚ Kohno Y‚ Tamari M‚ Hata A‚ Suzuki Y.   Association study of matrix metalloproteinase-12 gene polymorphisms and asthma in aJapanese population.
Int Arch Allergy Immunol  2012;   in press    

Inoue Y‚ Kawaguchi Y‚ Shimojo N‚ Yamaguchi K‚ Morita Y‚ Nakano T‚ Arima T‚ Tomiita M‚ Kohno Y   A case of infantile Takayasu arteritis with a p.D382E NOD2 mutation: An unusual phenotype of Blau syndrome/early-onset sarcoidosis?
Modern Rheumatology  2012;   in press    

Shiohama T‚ Fujii K‚ Hayashi M‚ Hishiki T‚ Suyama M‚ Mizuochi H‚ Uchikawa H‚ Yoshida S‚ Yoshida H‚ Kohno Y.   Phrenic nerve palsy associated with birth trauma - Case reports and a literature review.
Brain Dev.  2012;   in press    

Inoue Y‚ Ochiai H‚ Hishiki T‚ Shimojo N‚ Yoshida H‚ Kohno Y.   Food Allergy after Cord Blood Stem Cell Transplantation with Tacrolimus Therapy in Two Patients Who Developed Veno-Occlusive Disease.
Allergol Int.  2012;   in press    

Yonekura S‚ Okamoto Y‚ Shimojo N‚ Yamamoto H‚ Sakurai D‚ Horiguchi S‚ Hanazawa T‚ Inoue Y‚ Arima T‚ Tomiita M‚ Kohno Y.   The onset of allergic rhinitis in Japanese atopic children: A preliminary prospective study.
Acta Otolaryngol.  2012;   in press    

Kamemura N‚ Tada H‚ Shimojo N‚ Morita Y‚ Kohno Y‚ Ichioka T‚ Suzuki K‚ Kubota K‚ Hiyoshi M‚ Kido H.   Intrauterine sensitization of allergen-specific IgE analyzed by a highly sensitive new allergen microarray.
J Allergy Clin Immunol.  2012;   130   (1):   113-121

Kazato Y‚ Fujii K‚ Oba H‚ Hino M‚ Ochiai H‚ Uchikawa H‚ Kohno Y.   Reversible cerebral vasoconstriction syndrome associated with brain parenchymal hemorrhage.
Brain Dev.  2012;   in press    

Endo M‚ Fujii K‚ Sugita K‚ Saito K‚ Kohno Y‚ Miyashita T.   Nationwide survey of nevoid basal cell carcinoma syndrome in Japan revealing the low frequency of basal cell carcinoma.
Am J Med Genet A.  2012;   158A   (2):   351-357

Tashiro T‚ Shigeura T‚ Watarai H‚ Taniguchi M‚ Mori K.   RCAI-84‚ 91‚ and 105-108‚ ureido and thioureido analogs of KRN7000: Their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines.
Bioorg Med Chem.  2012;   20     4540-4548

Watarai H‚ Yamada D‚ Fujii S‚ Taniguchi M‚ Koseki H.   Induced pluripotency as a potential path towards iNKT cell-mediated cancer immunotherapy.
Int J Hematol.  2012;   95     624-631

Nagato K‚ Motohashi S‚ Ishibashi F‚ Okita K‚ Yamasaki K‚ Moriya Y‚ Hoshino H‚ Yoshida S‚ Hanaoka H‚ Fujii SI‚ Taniguchi M‚ Yoshino I‚ Nakayama T.   Accumulation of Activated Invariant Natural Killer T Cells in the Tumor Microenvironment after α-Galactosylceramide-Pulsed Antigen Presenting Cells.
J Clin Immunol.  2012;   in press    

Satoh M‚ Andoh Y‚ Clingan CS‚ Ogura H‚ Fujii S‚ Eshima K‚ Nakayama T‚ Taniguchi M‚ Hirata N‚ Ishimori N‚ Tsutsui H‚ Onoé K‚ Iwabuchi K.   Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation‚ steatohepatitis and insulin resistance.
PLoS One  2012;   7   (e30568):  

Yuumi Nakamura‚ Luigi Franchi‚ Naotomo Kambe‚ Guangxun Meng‚ Warren Strober‚ and Gabriel Nunez   Critical Role for Mast Cells in Interleukin-1b-Driven Skin Inflammation Associated with an Activating Mutation in the Nlrp3 Protein
Immunity  2012;   37     85-95

Iwasawa MT‚ Togawa Y‚ Akita F‚ Kambe N‚ Matsue H‚ Yaguchi T‚ Nishimura K   Kerion celsi due to Arthroderma incurvatum infection in a Sri Lankan child: species identification and analysis of area-dependent genetic polymorphism.
Med Mycol.  2012;   in press    

Wakabayashi S‚ Togawa Y‚ Yoneyama K‚ Suehiro K‚ Kambe N‚ Matsue H.   Dramatic Clinical Response of Relapsed Metastatic Extramammary Paget’s Disease to Trastuzumab Monotherapy.
Case Reports in Dermatological Medicine.  2012;   Article ID    

Sakai H‚ Okafuji I‚ Nishikomori R‚ Abe J‚ Izawa K‚ Kambe N‚ Yasumi T‚ Nakahata T‚ Heike T.   The CD40-CD40L axis and IFN-γ play critical roles in Langhans giant cell formation.
Int Immunol.  2012;   24     5-15

Yonekura S‚ Okamoto Y‚ Shimojo N‚ Yamamoto H‚ Sakurai D‚ Horiguchi S‚ Hanazawa T‚ Inoue Y‚ Arima T‚ Tomiita M‚ Kohno Y.   The onset of allergic rhinitis in Japanese atopic children: A preliminary prospective study.
Acta Otolaryngol.  2012;   132   (9):   981-987

Yamamoto H‚ Yonekura S‚ Sakurai D‚ Inamine A‚ Sakurai T‚ Iinuma T‚ Horiguchi S‚ Okamoto Y .   Comparison of nasal steroid with anti-histamine in prophylactic treatment against pollinosis using an environmental challenge chamber.
Allergy and Asthma Proceeding  2012;   33   (5):   397-403

Katada K‚Tomonaga T‚ Satoh M‚ Matsushita K‚ Tonoike Y‚ Kodera Y‚ Hanazawa T‚ Nomura F‚ Okamoto Y.   Plectin promotes migration and invasion of cancer cells and is a novel probnostic marker for head and neck squamous cell carcinoma.
Journal of Proteomics.  2012;   in press    

Yamasaki T‚ Seki N‚ Yamada Y‚ Yoshino H‚ Hidaka H‚ Chiyomaru T‚ Nohata N‚ Kinoshita T‚ Nakagawa M‚ Enokida H.   Tumor suppressive microRNA‑138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma.
Int J Oncol.   2012;   in press    

Isozaki Y‚ Hoshino I‚ Nohata N‚ Kinoshita T‚ Akutsu Y‚ Hanari N‚ Mori M‚ Yoneyama Y‚ Akanuma N‚ Takeshita N‚ Maruyama T‚ Seki N‚ Nishino N‚ Yoshida M‚ Matsubara H.   Identification of novel molecular targets regulated by tumor suppressive miR-375 induced by histone acetylation in esophageal squamous cell carcinoma.
Int J Oncol.   2012;   in press    

Kinoshita T‚ Hanazawa T‚ Nohata N‚ Okamoto Y‚ Seki N.   The functional significance of microRNA-375 in human squamous cell carcinoma: aberrant expression and effects on cancer pathways.
J Hum Genet.  2012;   in press    

Yamasaki T‚ Yoshino H‚ Enokida H‚ Hidaka H‚ Chiyomaru T‚ Nohata N‚ Kinoshita T‚ Fuse M‚ Seki N‚ Nakagawa M.   Novel molecular targets regulated by tumor suppressors microRNA-1 and microRNA-133a in bladder cancer.
Int J Oncol.   2012;   40   (6):   1821-1830

Kinoshita T‚ Nohata N‚ Yoshino H‚ Hanazawa T‚ Kikkawa N‚ Fujimura L‚ Chiyomaru T‚ Kawakami K‚ Enokida H‚ Nakagawa M‚ Okamoto Y‚ Seki N.   microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma.
Int J Oncol.  2012;   40   (1):   185-193

Hidaka H‚ Seki N‚ Yoshino H‚ Yamasaki T‚ Yamada Y‚ Nohata N‚ Fuse M‚ Nakagawa M‚ Enokida H.   Tumor suppressive microRNA-1285 regulates novel molecular targets: aberrant expression and functional significance in renal cell carcinoma.
Oncotarget. Review  2012;   1     44-57

Kinoshita T‚ Nohata N‚ Watanabe-Takano H‚ Yoshino H‚ Hidaka H‚ Fujimura L‚ Fuse M‚ Yamasaki T‚ Enokida H‚ Nakagawa M‚ Hanazawa T‚ Okamoto Y‚ Seki N.   Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma.
Int J Oncol.  2012;   40   (6):   1770-1778

Nohata N‚ Hanazawa T‚ Enokida H‚ Seki N.   microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers.
Oncotarget. Review  2012;   3   (1):   9-21

Kinoshita T‚ Nohata N‚ Fuse M‚ Hanazawa T‚ Kikkawa N‚ Fujimura L‚ Watanabe-Takano H‚ Yamada Y‚ Yoshino H‚ Enokida H‚ Nakagawa M‚ Okamoto Y‚ Seki N.   Tumor suppressive microRNA-133a regulates novel targets: moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma.
Biochem Biophys Res Commun.  2012;   418   (2):   378-383

Inamine A‚ Sakurai D‚ Horiguchi S‚ Yonekura S‚ Hanazawa T‚ Hosokawa H‚ Matuura-Suzuki A‚ Nakayama T‚ Okamoto Y.   Sublingual administration of Lactobacillus paracasei KW3110 inhibits Th2-dependent allergic responses via upregulation of PD-L2 on dendritic cells.
Clinical Immunology.  2012;   143     170-179

Inoue H‚ Mashimo Y‚ Funamizu M‚ Yonekura S‚ Shigtoshi H‚ Shimojo N‚ Kohno Y‚ Okamoto Y‚ Hata A‚ Suzuki Y.   Association of the MMP9 gene with childhood cedar pollen sensitization and pollinosis.
J Hum Genet on line publication  2012;       1-8

Aoyagi Y‚ Kuroda M‚ Asada S‚ Tanaka S‚ Tanio M‚ Aso M‚ Okamoto Y‚ Nakayama T‚ Saito Y‚ Bujo H.   Fibrin glue is a candidate scafford for long-term therapeutic protein expression in spontaneously differentiated adipocytes in vitro.
Experimental Cell Reseach  2012;   318     1090-1112

Iwata A‚ Ikeda K‚ Hirose K‚ Takatori H‚ Takahashi K‚ Suzuki Y‚ Tanaka S‚ Suto A‚ Nakajima H.   Pre-dinner administration increases the efficacy of proton pump inhibitors on refractory GERD symptoms in connective tissue disease patients.
Mod Rheumatol  2012;   in press    

Yoh K‚ Morito N‚ Ojima M‚ Shibuya K‚ Yamashita Y‚ Morishima Y‚ Ishii Y‚ Kusakabe M‚ Nishikii H‚ Fujita A‚ Matsunaga E‚ Okamura M‚ Hamada M‚ Suto A‚ Nakajima H‚ Shibuya A‚ Yamagata K‚ Takahashi S.   Overexpression of RORγt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice.
Eur. J. Immunol.  2012;   in press    

Okada S‚ Yokoyama M‚ Toko H‚ Tateno K‚ Moriya J‚ Shimizu I‚ Nojima A‚ Ito T‚ Yoshida Y‚ Kobayashi Y‚ Katagiri H‚ Minamino T‚ Komuro I   Brain-Derived Neurotrophic Factor Protects Against Cardiac Dysfunction After Myocardial Infarction via a Central Nervous System-Mediated Pathway.
Arterioscler Thromb Vasc Biol.  2012;   in press    

Naito AT‚ Sumida T‚ Nomura S‚ Liu ML‚ Higo T‚ Nakagawa A‚ Okada K‚ Sakai T‚ Hashimoto A‚ Hara Y‚ Shimizu I‚ Zhu W‚ Toko H‚ Katada A‚ Akazawa H‚ Oka T‚ Lee JK‚ Minamino T‚ Nagai T‚ Walsh K‚ Kikuchi A‚ Matsumoto M‚ Botto M‚ Shiojima I‚ Komuro I   Complement c1q activates canonical wnt signaling and promotes aging-related phenotypes.
Cell Metab  2012;   149   (6):   1298-1313

Kameda Y‚ Hasegawa H‚ Kubota A‚ Tadokoro H‚ Kobayashi Y‚ Komuro I‚ Takano H.   Effects of pitavastatin on pressure overload-induced heart failure in mice.
Circ J.  2012;   76   (5):   1159-1168

Uchiyama R‚ Hasegawa H‚ Kameda Y‚ Ueda K‚ Kobayashi Y‚ Komuro I‚ Takano H.   Role of regulatory T cells in atheroprotective effects of granulocyte colony-stimulating factor.
J Mol Cell Cardiol  2012;   52   (5):   1038-1047

Hasegawa H‚ Takano H‚ Kameda Y‚ Kubota A‚ Kobayashi Y‚ Komuro I.   Effect of switching from telmisartan‚ valsartan‚ olmesartan‚ or losartan to candesartan on morning hypertension.
Clin Exp Hypertens.  2012;   34   (2):   86-91

Shimizu I‚ Yoshida Y‚ Katsuno T‚ Tateno K‚ Okada S‚ Moriya J‚ Yokoyama M‚ Nojima A‚ Ito T‚ Zechner R‚ Komuro I‚ Kobayashi Y‚ Minamino T.   p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure.
Cell Metab  2012;   15   (1):   51-64

Onouchi Y‚ Ozaki K‚ Burns JC‚ Shimizu C‚ Terai M‚ Hamada H‚ Honda T‚ Suzuki H‚ Suenaga T‚ Takeuchi T‚ Yoshikawa N‚ Suzuki Y‚ Yasukawa K‚ Ebata R‚ Higashi K‚ Saji T‚ Kemmotsu Y‚ Takatsuki S‚ Ouchi K‚ Kishi F‚ Yoshikawa T‚ Nagai T‚ Hamamoto K‚ Sato Y‚ Honda A‚ Kobayashi H‚ Sato J‚ Shibuta S‚ Miyawaki M‚ Oishi K‚ Yamaga H‚ Aoyagi N‚ Iwahashi S‚ Miyashita R‚ Murata Y‚ Sasago K‚ Takahashi A‚ Kamatani N‚ Kubo M‚ Tsunoda T‚ Hata A‚ Nakamura Y‚ Tanaka T; Japan Kawasaki Disease Genome Consortium‚ Abe J‚ Kobayashi T‚ Arakawa H‚ Ichida F‚ Nomura Y‚ Miura M‚ Ikeda K‚ Hara T‚ Fukazawa R‚ Ogawa S‚ Hamaoka K; US Kawasaki Disease Genetics Consortium‚ Newburger JW‚ Baker AL‚ Rowley AH‚ Shulman ST‚ Melish ME‚ Mason WH‚ Takahashi M‚ Tremoulet AH   A genome-wide association study identifies three new risk loci for Kawasaki disease.
Nat Genet.  2012;   44     517-521

Yamaide F‚ Undarmaa S‚ Mashimo Y‚ Shimojo N‚ Arima T‚ Morita Y‚ Hirota T‚ Fujita K‚ Miyatake A‚ Doi S‚ Sato K‚ Suzuki S‚ Nishimura T‚ Watanabe H‚ Hoshioka A‚ Tomita M‚ Yamaide A‚ Watanabe M‚ Okamoto Y‚ Kohno Y‚ Tamari M‚ Hata A‚ Suzuki Y.   Association study of matrix metalloproteinase-12 gene polymorphisms and asthma in a Japanese population
International Archives of Immunology and Immunology  2012;   in press    

Nagai‚ M.‚ Furihata‚ T.‚ Matsumoto‚ S.‚ Ishii‚ S.‚ Motohashi‚ S.‚ Yoshino‚ I.‚ Ugajin‚ M.‚ Miyajima‚ A.‚ Matsumoto‚ S. and Chiba‚ K.   Identification of a new organic anion transporting polypeptide 1B3 mRNA isoform primarily expressed in human cancerous tissues and cell
Biochem Biophys Res Commun  2012;   418   (4):   818-823

Iikura‚ M.‚ Furihata T.‚ Mizuguchi‚ M.‚ Nagai‚ M.‚ Ikeda‚ M.‚ Kato‚ N.‚ Tsubota‚ A. and Chiba‚ K.   ENT1‚ a ribavirin transporter ‚plays a pivotal role in antiviral efficacy of ribavirin in a hepatitis C virus replication cell system
Anitimicrob Agents Chemother  2012;   56   (39):   1407-1413

Hori‚ T.‚ Jin‚ L.‚ Fujii‚ A.‚ Furihata‚ T.‚ Nagahara‚ Y.‚ Chiba‚ K. and Hosokowa‚ M.   Dexamethasone-mediated transcriptional regulation of rat carboxylesterase 2 gene
Xenobiotica  2012;   42   (7):   614-623

Tsubota‚ A.‚ Shimada‚ N.‚ Yoshizawa‚ K.‚ Agata‚ R.‚ Furihata‚ T.‚ Yumoto‚ Y.‚ Abe‚ H.‚ Ika‚ M.‚ Namiki‚ Y.‚ Chiba‚ K.‚ Fujise‚ K.‚ Tada‚ T. and Aizawa‚ Y.   Contoribution of ribavirin transporter gene polymorphism to treatment response in peginterferon plus ribavirin therapy for HCV genotype 1b patients
Liver Int  2012;   32   (5):   826-836

Nakaoka H‚ Kanegane H‚ Taneichi H‚ Miya K‚ Yang X‚ Nomura K‚ Takezaki S‚ Yamada M‚ Ohara O‚ Kamae C‚ Imai K‚ Nonoyama S‚ Wada T‚ Yachie A‚ Hershfield MS‚ Ariga T‚ Miyawaki T.   Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis.
Int J Hematol.  2012;   95   (6):   692-696

Mohammadzadeh I‚ Yeganeh M‚ Aghamohammadi A‚ Parvaneh N‚ Behniafard N‚ Abolhassani H‚ Tabassomi F‚ Hemmat M‚ Kanegane H‚ Miyawaki T‚ Ohara O‚ Rezaei N.   Severe primary antibody deficiency due to a novel mutation of micro heavy chain.
J Investig Allergol Clin Immunol.  2012;   22   (1):   78-79

Tofukuji S‚ Kuwahara M‚ Suzuki J‚ Ohara O‚ Nakayama T‚ Yamashita M.   Identification of a New Pathway for Th1 Cell Development Induced by Cooperative Stimulation with IL-4 and TGF-β.
Immunol.  2012;   188   (10):   4846-4857

Suri D‚ Singh S‚ Rawat A‚ Gupta A‚ Kamae C‚ Honma K‚ Nakagawa N‚ Imai K‚ Nonoyama S‚ Oshima K‚ Mitsuiki N‚ Ohara O‚ Bilhou-Nabera C‚ Proust A‚ Ahluwalia J‚ Dogra S‚ Saikia B‚ Minz RW‚ Sehgal S.   Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh‚ North India.
Asian Pac J Allergy Immunol.  2012;   30   (1):   71-78

Takezaki S‚ Yamada M‚ Kato M‚ Park MJ‚ Maruyama K‚ Yamazaki Y‚ Chida N‚ Ohara O‚ Kobayashi I‚ Ariga T.   Chronic Mucocutaneous Candidiasis Caused by a Gain-of-Function Mutation in the STAT1 DNA-Binding Domain.
J Immunol.  2012;   In press    

Fukaya T‚ Murakami R‚ Takagi H‚ Sato K‚ Sato Y‚ Otsuka H‚ Ohno M‚ Hijikata A‚ Ohara O‚ Hikida M‚ Malissen B‚ Sato K.   Conditional ablation of CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo.
Proc Natl Acad Sci U S A.  2012;   In press    

Lavial‚ F.‚ Bessonnard‚ S.‚ Ohnishi‚ Y.‚ Tsumura‚ A.‚ Chandrashekran‚ A.‚ Fenwick‚ M.‚ Tomaz‚ R. A.‚ Hosokawa‚ H.‚ Nakayama‚ T.‚ Chambers‚ I.‚ Hiiragi‚ T.‚ Chazaud‚ C.‚ and Azuara‚ V.   Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development.
Genes Dev.  2012;   In press    

Nagato‚ K.‚ Motohashi‚ S.‚ Ishibashi‚ F.‚ Okita‚ K.‚ Yamasaki‚ K.‚ Moriya‚ Y.‚ Hoshino‚ H.‚ Yoshida‚ S.‚ Hanaoka‚ H.‚ Fuji‚ S.‚ Taniguchi‚ M.‚ Yoshino‚ I.‚ and Nakayama‚ T.   Accumulation of activated invariant natural killer T cells in the tumor microenvironment after α-Galactosylceramide-pulsed antigen presenting cells.
J. Clin. Immunol.  2012;   In press    

Watanabe‚ M.‚ Nakajima‚ S.‚ Ohnuki‚ K.‚ Ogawa‚ S.‚ Yamashita‚ M.‚ Nakayama‚ T.‚ Murakami‚ Y.‚ Tanabe‚ K.‚ and Abe‚ R.   The transcription factor AP-1 is involved in ICOS gene expression downstream of TCR/CD28 signaling and cytokine receptor signaling.
Eur. J. Immunol.  2012;   In press    

Radulovic‚ K.‚ Manta‚ C.‚ Rossini‚ V.‚ Holzmann‚ K.‚ Kestler‚ H. A.‚ Wegenka‚ U. M.‚ Nakayama‚ T.‚ and Niess‚ J. H.   CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential.
J Immunol.  2012;   188   (4):   2001-2013

Shinoda‚ K.‚ Tokoyoda‚ K.‚ Hanazawa‚ A.‚ Hayashizaki‚ K.‚ Zehentmeier‚ S.‚ Hosokawa‚ H.‚ Iwamura‚ C.‚ Koseki‚ H.‚ Tumes‚ J. D.‚ Radbruch‚ A.‚ and Nakayama‚ T.   Type II membrane protein CD69 regulates the formation of resting T-helper memory.
Proc Natl Acad Sci U S A.  2012;   109   (19):   7409-7414

Tofukuji‚ S.‚ Kuwahara‚ M.‚ Suzuki‚ J.‚ Ohara‚ O.‚ Nakayama‚ T.‚ and Yamashita‚ M.   Identification of a new pathway for Th1 cell development induced by cooperative stimulation with IL-4 and TGFβ.
J.Immunol.  2012;   188   (10):   4846-4857

Ishizaki‚ S.‚ Kasuya‚ Y.‚ Kuroda‚ F.‚ Tanaka‚ K.‚ Tsuyusaki‚ J.‚ Yamauchi‚ K.‚ Matsunaga‚ H.‚ Iwamura‚ C.‚ Nakayama‚ T.‚ and Tatsumi‚ K.   Role of CD69 in acute lung injury.
Life Sciences  2012;   90   (17-18):   657-665

Inamine‚ A.‚ Sakurai‚ D.‚ Horiguchi‚ S.‚ Yonekura‚ S.‚ Hanazawa‚ T.‚ Hosokawa‚ H.‚ Matuura-Suzuki‚ A.‚ Nakayama‚ T.‚ and Okamoto‚ Y.   Sublingual administration of Lactobacillus paracasei KW3110 inhibits Th2-dependent allergic responses via upregulation of PD-L2 on dendritic cells.
Clin.Immunol.  2012;   143   (2):   170-179

Miyasaka‚ T.‚ Aoyagi‚ T.‚ Uchiyama‚ B.‚ Oishi‚ K.‚ Nakayama‚ T.‚ Kinjo‚ Y.‚ Miyazaki‚ Y.‚ Kunishima‚ H.‚ Hirakata‚ Y.‚ Kaku‚ M.‚ and Kawakami‚ K.   A possible relationship of natural killer T cells with humoral immune response to 23-valent pneumococcal polysaccharide vaccine in clinical settings
Vaccine  2012;   39   (22):   3304-3310

Nagato‚ K.‚ Motohashi‚ S.‚ Ishibashi‚ F.‚ Okita‚ K.‚ Yamasaki‚ K.‚ Moriya‚ Y.‚ Hoshino‚ H.‚ Yoshida‚ S.‚ Hanaoka‚ H.‚ Fuji‚ S.‚ Taniguchi‚ M.‚ Yoshino‚ I.‚ and Nakayama‚ T.   Accumulation of activated invariant natural killer T cells in the tumor microenvironment after α-Galactosylceramide-pulsed antigen presenting cells.
Clin.Immunol.  2012;   In press    

Kuwahara‚ M.‚ Yamashita‚ M.‚ Shinoda‚ K.‚ Tofukuji‚ S.‚ Onodera‚ A.‚ Shinnakasu‚ R.‚ Motohashi‚ S.‚ Hosokawa‚ H.‚ Tumes‚ D.‚ Iwamura‚ C.‚ Lefebvre‚ V.‚ and Nakayama‚ T.:   The transcription factor Sox4 is a downstream target of TGF-β signaling and suppresses GATA3-induced TH2 cell differentiation.
Nat. Immunol.  2012;   13   (8):   778-786

Shigeta‚ A.‚ Tada‚ Y.‚ Wang‚ J.Y.‚ Ishizaki‚ S.‚ Tsuyusaki‚ J.‚ Yamauchi‚ K.‚ Kasahara‚ Y.‚ Iesato‚ K.‚ Tanabe‚ N.‚ Takiguchi‚ Y.‚ Sakamoto‚ A.‚ Tokuhisa‚ T.‚ Shibuya‚ K.‚ Hiroshima‚ K.‚ West‚ J.‚ and Tatsumi‚ K.   CD40 amplifies Fas-mediated apoptosis: a mechanism contributing to emphysema.
Am J Physiol Lung Cell Mol Physiol  2012;   109     2699-2706

Ohnuki‚ H.‚ Inoue‚ H.‚ Takemori‚ N.‚ Nakayama‚ H.‚ Sakaue‚ T.‚ Fukuda‚ S.‚ Miwa‚ D.‚ Nishiwaki‚ E.‚ Hatano‚ M.‚ Tokuhisa‚ T.‚ Endo‚ Y.‚ Nose‚ M.‚ and Higashiyama‚ S.   BAZF‚ a novel component of cullin3-based E3 ligase complex‚ mediates VEGFR and Notch cross-signalling in angiogenesis.
Blood  2012;   119     2688-2698

Yokoyama S‚ Yamashita S‚ Ishibashi S‚ Sone H‚ Oikawa S‚ Shirai K‚ Ohta T‚ Bujo H‚ Kobayashi J‚ Arai H‚ Harada-Shiba M‚ Eto M‚ Hayashi T‚ Gotoda T‚ Suzuki H‚ Yamada N.   Background to discuss guidelines for control of plasma HDL-cholesterol in Japan.
J Atheroscler Thromb.  2012;   19   (3):   207-212

Guo LH‚ Westerteicher C‚ Wang XH‚ Kratzer M‚ Tsolakidou A‚ Jiang M‚ Grimmer T‚ Laws SM‚ Alexopoulos P‚ Bujo H‚ Kurz A‚ Perneczky R.   SORL1 genetic variants and cerebrospinal fluid biomarkers of Alzheimer’s disease.
Eur Arch Psychiatry Clin Neurosci.  2012;   in press    

Fukaya Y‚ Kuroda M‚ Aoyagi Y‚ Asada S‚ Kubota Y‚ Okamoto Y‚ Nakayama T‚ Saito Y‚ Satoh K‚ Bujo H.   Platelet-rich plasma inhibits the apoptosis of highly adipogenic homogeneous preadipocytes in an in vitro culture system..
Exp Mol Med.  2012;   44   (5):   330-339

Takahashi M‚ Bujo H‚ Shiba T‚ Jiang M‚ Maeno T‚ Shirai K.   Enhanced Circulating Soluble LR11 in Patients With Diabetic Retinopathy.
Am J Ophthalmol.  2012;   154   (1):   187-192

Nagai‚ M.‚ Furihata‚ T.‚ Matsumoto‚ S.‚ Ishii‚ S.‚ Motohashi‚ S.‚ Yoshino‚ I.‚ Ugajin‚ M.‚ Miyajima‚ A.‚ Matsumoto‚ S.‚ Chiba‚ K.   Identification of a new organic anion transporting polypeptide 1B3 mRNA isoform primarily expressed in human cancerous tissues and cells.
Biochem Biophys Res Commun.  2012;   418   (4):   818-823

Yamashita‚ J.‚ Iwamura‚ C.‚ Mitsumori‚ K.‚ Hosokawa‚ H.‚ Sasaki‚ T.‚ Takahashi‚ M.‚ Tanaka‚ H.‚ Kaneko‚ K.‚ Hanazawa‚ A.‚ Watanabe‚ Y.‚ Shinoda‚ K.‚ Tumes‚ D.‚ Motohashi‚ S.‚ Nakayama‚ T.   Murine Schnurri-2 controls Natural Killer cell function and lymphoma development.
Leuk. Lymphoma  2012;   53   (3):   479-486

Takeuchi K‚ Umeki Y‚ Matsumoto N‚ Yamamoto K‚ Yoshida M‚ Suzuki K‚ Aratani Y.   Severe neutrophil-mediated lung inflammation in myeloperoxidase-deficient mice exposed to zymosan.
Inflammation Res  2012;   6   (13):   197-205

Hayashi D‚ Tamura A‚ Tanaka H‚ Yamazaki Y‚ Watanabe S‚ Suzuki K‚ Suzuki K‚ Sentani K‚ Yasui W‚ Rakugi H‚ IsakaY‚ Tsukita S.   Defiency of claudin-18 causes paracellular H+ leakage‚ up-regulation of interleukin-1 beta‚ and atrophic gastritis in mice.
Gastroenterology  2012;   142   (2):   292-304

Fujimori Y‚ Sato T‚ Hayata T‚ Nagao T‚ Nakayama M‚ Nakayama T‚ Sugamata R‚ Suzuki K.   Novel anti-viral characters of nanosized copper(I) iodide particles showing inactivation activity against 2009 pandeminc H1N1 influenza virus.
Applied Environ Microbiol  2012;   78   (4):   951-955

Koshio O‚ Nagao T‚ Mabuchi A‚ Ono Y‚ Suzuki K.   Apoptotic signaling in endothelial cells with neutrophil activation.
Mol Cell Biochem  2012;   363   (1-2):   269-280

Shitara‚ Y.‚ Takeuchi‚ K.‚ Nagamatsu‚ Y.‚ Wada‚ S.‚ Sugiyama‚ Y.‚ and Horie‚ T.   Long-lasting inhibitory effects of cyclosporin A‚ but not tacrolimus‚ on OATP1B1- and OATP1B3-mediated uptake.
Drug Metab. Pharmacokinet.  2012;   27   (4):   368-378

Koshizaka M‚ Takemoto M‚ Sato S‚ Tokuyama H‚ Fujimoto M‚ Okabe E‚ Ishibashi R‚ Ishikawa T‚ Tsurutani Y‚ Onishi S‚ Mezawa M‚ He P‚ Honjo S‚ Ueda S‚ Saito Y‚ Yokote K   An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice
Experimental Diabetes Research  2012;   in press    

Tanaka H‚ Ohwada C‚ Hashimoto S‚ Sakai S‚ Takeda Y‚ Abe D‚ Takagi T‚ Ohshima K‚ Nakaseko C.   Leukemic presentation of ALK-negative anaplastic large cell lymphoma in a patient with myelodysplastic syndrome.
Intern Med  2012;   51   (2):   199-203

Shimizu N‚ Nakaseko C‚ Sakaida E‚ Ohwada C‚ Takeuchi M‚ Tanaka S‚ Muto T‚ Kawaguchi T‚ Tsukamoto S‚ Sakai S‚ Takeda Y‚ Abe D‚ Yokote K‚ Iseki T‚ Kanai K‚ Misawa S‚ Kuwabara S.   Factors associated with the efficiency of peripheral blood stem cell harvest in patients with POEMS syndrome undergoing autologous peripheral blood stem cell transplantation.
Bone Marrow Transplant  2012;      

Sazuka S‚ Takahashi Y‚ Sato T‚ Nakagawa T‚ Furuya Y‚ Saito M‚ Saito K‚ Kawaguchi T‚ Nakaseko C‚ Katsuno T‚ Yokosuka O.   Endoscopic findings of small intestinal EBV-associated T-cell lymphoproliferative disorder.
Endoscopy  2012;       E30-E31

Sugamata R‚ Dobashi H‚ Nagao T‚ Yamamoto K‚ Nakajima N‚ Sato Y‚ Aratani Y‚ Oshima M‚ Sata T‚ Kobayashi K‚ Kawachi S‚ Nakayama T‚ Suzuki K.   The contribution of neutrophil-derived myeloperoxidase in the early phase of fulminant acute respiratory distress syndrome induced by influenza virus infection.
Microbiol Immunol.  2012;   56   (3):   171-182

Uekusa Y‚ Inamine A‚ Yonekura S‚ Horiguchi S‚Fujimura T‚Sakurai D‚ Yamamoto‚Hanazawa T‚Okamoto Y.   Immunological parameters with the development of allergics rhinitis:A preliminary prospective study.
Am J Rhinol Alleg.  2012;   26   (2):   92-96

Aoysgi Y‚Kuroda M‚Asada S‚Tanaka S‚Tanio M‚Aso M‚Okamoto Y‚Nakayama T‚Saito Y‚Bujo H.   Fibrin glue is a candidate scaffold for long-term therapeutic protein expression in spontaneously differentiated adipocytes vitro.
Experimental Cell Reseach  2012;   318   (1):   1090-1112

Katada K‚ Tomonaga T‚ Satoh M‚ Matsushita K‚ Tonoike Y‚ Kodera Y‚ Hanazawa T‚ Nomura F‚ Okamoto Y.   Plectin promotes migration and invasion of cancer cells and is a novel prognostic marker for head and neck squamous cell carcinoma.
J Proteomics  2012;   75   (6):   1803-1815

Yonekura S‚ Okamoto Y‚ Horiguchi S‚ Sakurai D‚ Chazono H‚ Hanazawa T‚ Okawa T‚ Aoki S‚ Konno A.   Effects of aging on the natural history of seasonal allergic rhinitis in middle-aged subjects in South chiba‚ Japan.
Int Arch Allergy Immunol.  2012;   157   (1):   73-80

Ayako Inamine‚Daijyu Sakurai‚ Shigetoshi Horiguchi‚ Syu-ji Yonekura‚ Toyoyuki Hanazawa‚ Hiroyuki Hosakawa‚ Asaka Matuura-Suzuki‚Toshinori Nakayama‚ Yoshitaka Okamoto‚   Sublingual administration of Lactobacillus paracasei KW3110 inhibits Th2-dependent allergic responses via upregulation of PD-L2 on dendritic cells.
Clin Immunol.  2012;   143   (2):   170-179

Kawakami K‚ Enokida H‚ Chiyomaru T‚ Tatarano S‚ Yoshino H‚ Kagara I‚ Gotanda T‚ Tachiwada T‚ Nishiyama K‚ Nohata N‚ Seki N‚ Nakagawa M.   The functional significance of miR-1 and miR-133a in renal cell carcinoma.
Eur J Cancer.  2012;   48   (6):   827-836

Yoshino H‚ Enokida H‚ Kawakami K‚ Chiyomaru T‚ Tatarano S‚ Hidaka H‚ Yamasaki T‚ Gotanda T‚ Tachiwada T‚ Nohata N‚ Nishiyama K‚ Seki N‚ Nakagawa M.   Tumor suppressive microRNA-1 mediated novel apoptosis pathways through direct inhibition of splicing factor arginine/serine-rich 9 (SRSF9/SRp30c) in bladder cancer.
Biochem Biophys Res Commun.  2012;   417   (1):   588-593

Tatarano S‚ Chiyomaru T‚ Kawakami K‚ Enokida H‚ Yoshino H‚ Hidaka H‚ Nohata N‚ Yamasaki T‚ Gotanda T‚ Tachiwada T‚ Seki N‚ Nakagawa M.   Novel oncogenic function of mesoderm development candidate 1 (MESDC1) and its regulation by MiR-574-3p in baldder cancer cell lines.
Int J Oncol.  2012;   40   (4):   951-959

Kojima S‚ Chiyomaru T‚ Kawakami K‚ Yoshino H‚ Enokida H‚ Nohata N‚ Fuse M‚ Ichikawa T‚ Naya Y‚ Nakagawa M‚ Seki N.   Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer.
Br J Cancer.  2012;   106   (2):   405-413

Moriya Y‚ Nohata N‚ Kinoshita T‚ Mutallip M‚ Okamoto T‚ Yoshida S‚Suzuki M‚ Yoshino I‚ Seki N.   Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma.
J Hum Genet.  2012;   57   (1):   38-45

Kinoshita T‚ Nohata N‚ Yoshino H‚ Hanazawa T‚ Kikkawa N‚ Fujimura L‚ Chiyomaru T‚ Kawakami K‚ Enokida H‚ Nakagawa M‚ Okamoto Y‚ Seki N.   Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma.
Int J Oncol.  2012;   40   (1):   185-193

Okamoto N‚ Hayashi S‚ Masui A‚ Kosaki R‚ Oguri I‚ Hasegawa T‚ Imoto I‚ Makita Y‚ Hata A‚ Moriyama K‚ Inazawa J.   Deletion at chromosome 10p11.23-p12.1 defines characteristic phenotypes with marked midface retrusion.
J Hum Genet.  2012;   57   (3):   191-196

Inoue H‚ Mashimo Y‚ Funamizu M‚ Yonekura S‚ Horiguchi S‚ Shimojo N‚ Kohno Y‚ Okamoto Y‚ Hata A‚ Suzuki Y.   Association of the MMP9 gene with childhood cedar pollen sensitization and pollinosis.
J Hum Genet.  2012;   57   (3):   176-183

Narisawa A‚ Komatsuzaki S‚ Kikuchi A‚ Niihori T‚ Aoki Y‚ Fujiwara K‚ Tanemura M‚ Hata A‚ Suzuki Y‚ Relton CL‚ Grinham J‚ Leung KY‚ Partridge D‚ Robinson A‚ Stone V‚ Gustavsson P‚ Stanier P‚ Copp AJ‚ Greene ND‚ Tominaga T‚ Matsubara Y‚ Kure S.   Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans.
Hum Mol Genet.  2012;   21   (7):   1496-1503

Onouchi Y‚ Suzuki Y‚ Suzuki H‚ Terai M‚ Yasukawa K‚ Hamada H‚ Suenaga T‚ Honda T‚ Honda A‚ Kobayashi H‚ Takeuchi T‚ Yoshikawa N‚ Sato J‚ Shibuta S‚ Miyawaki M‚ Oishi K‚ Yamaga H‚ Aoyagi N‚ Iwahashi S‚ Miyashita R‚ Murata Y‚ Ebata R‚ Higashi K‚ Ozaki K‚ Sasago K‚ Tanaka T‚ Hata A.   ITPKC and CASP3 polymorphisms and risks for IVIG unresponsiveness and coronary artery lesion formation in Kawasaki disease.
Pharmacogenomics J.  2012;   in press    

Hayashi S‚ Okamoto N‚ Chinen Y‚ Takanashi J‚ Makita Y‚ Hata A‚ Imoto I‚ Inazawa J.   Novel intragenic duplications and mutations of CASK in patients with mental retardation and microcephaly with pontine and cerebellar hypoplasia (MICPCH).
Hum Genet.  2012;   131     99-110

Yamatoji M‚ Kasamatsu A‚ Kouzu Y‚ Koike H‚ Sakamoto Y‚ Ogawara K‚ Shiiba M‚ Tanzawa H‚ Uzawa K.   Dermatopontin: A potential predictor for metastasis of human oral cancer.
Int J Cancer.  2012;   130   (12):   2903-2911

Ishiwata J‚ Kasamatsu A‚ Sakuma K‚ Iyoda M‚ Yamatoji M‚ Usukura K‚ Ishige S‚ Shimizu T‚ Yamano Y‚ Ogawara K‚ Shiiba M‚ Tanzawa H‚ Uzawa K.   State of heat shock factor 1 expression as a putative diagnostic marker for oral squamous cell carcinoma.
Int J Oncol.  2012;   40   (1):   47-52

Ono K‚ Shiiba M‚ Yoshizaki M‚ Ogawara K‚ Ishihara T‚ Yonemori Y‚ Oide T‚ Uzawa K‚ Nakatani Y‚ Tanzawa H.   Immunoglobulin G4-Related Sclerosing Inflammatory Pseudotumors Presenting in the Oral Cavity.
J Oral Maxillofac Surg.  2012;   in press    

Uchibori K‚ Kasamatsu A‚ Sunaga M‚ Yokota S‚ Sakurada T‚ Kobayashi E‚ Yoshikawa M‚ Uzawa K‚ Ueda S‚ Tanzawa H‚ Sato N.   Establishment and characterization of two 5-fluorouracil-resistant hepatocellular carcinoma cell lines.
Int J Oncol.  2012;   40   (4):   1005-1010

Uehara E‚ Shiiba M‚ Shinozuka K‚ Saito K‚ Kouzu Y‚ Koike H‚ Kasamatsu A‚ Sakamoto Y‚ Ogawara K‚ Uzawa K‚ Tanzawa H.   Upregulated expression of ADAM12 is associated with progression of oral squamous cell carcinoma.
Int J Oncol.  2012;   40   (5):   1414-1422

Ota‚ R‚ Iwasawa‚ M.T. ‚ Ohkusu‚ K. ‚ Kambe‚ N. ‚ Matsue‚ H.   Maximum growth temperature test for cutaneous Mycobacterium chelonae predicts the efficacy of thermal therapy.
Journal of Dermatology  2012;   39   (2):   205-206

Li‚ K.‚ Yao‚ J. ‚ Shi‚ L. ‚ Sawada‚ N.‚ Chi‚ Y.‚ Yan‚ Q.‚ Matsue‚ H.‚ Kitamura‚ M.‚ Takeda‚ M.   Reciprocal regulation between proinflammatory cytokine-induced inducible NO synthase (iNOS) and connexin43 in bladder smooth muscle cells.
Journal of Biological Chemistry  2012;   286   (48):   41552-41562

Mizuno T‚ Sakai H‚ Nishikomori R‚ Oshima K‚ Ohara O‚ Hata I‚ Shigematsu Y‚ Ishige T‚ Tamura K‚ Arakawa H.   Novel mutations of MVK gene in Japanese family members affected with hyperimmunoglobulinemia D and periodic fever syndrome.
Rheumatol Int.  2012;   in press    

Takagi S‚ Saito Y‚ Hijikata A‚ Tanaka S‚ Watanabe T‚ Hasegawa T‚ Mochizuki S‚ Kunisawa J‚ Kiyono H‚ Koseki H‚ Ohara O‚ Saito T‚ Taniguchi S‚ Shultz LD‚ Ishikawa F.   Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.
Blood.  2012;   119   (12):   2768-2777

Izawa K‚ Hijikata A‚ Tanaka N‚ Kawai T‚ Saito MK‚ Goldbach-Mansky R‚ Aksentijevich I‚ Yasumi T‚ Nakahata T‚ Heike T‚ Nishikomori R‚ Ohara O.   Detection of Base Substitution-Type Somatic Mosaicism of the NLRP3 Gene with >99.9% Statistical Confidence by Massively Parallel Sequencing.
DNA Res.  2012;   19   (2):   143-152

Akutsu Y‚ Yasuda S‚ Nagata M‚ Izumi Y‚ Okazumi S‚ Shimada H‚ Nakatani Y‚ Tsujii H‚ Kamada T‚ Yamada S‚ Matsubara H‚   A phase l/ll clinical trial of preoperative short-course carbon-ion radiotherapy for patients with aquamous cell carcinoma of the esophagus.
J Surg Oncol  2012;   105   (8):   750-755

Nakagomi D‚ Ikeda K‚ Kawashima H‚ Kobayashi Y‚ Suto A‚ Nakajima H.   Bucillamine-induced yellow nail in Japanese patients with rheumatoid arthritis: two case reports and a review of 33 reported cases.
Rheumatol Int  2012;   in press    

Saito Y‚ Kagami S-I‚ Kawashima S‚ Takahashi K‚ Ikeda K‚ Hirose K‚ Oshitari T‚ Yamamoto S‚ Okamoto Y‚ Nakajima H   Roles of CRTH2+ CD4+ T cells in IgG4-related lacrimal gland enlargement.
Int. Arch. Allergy Immunol  2012;   158     42-46

Watarai H‚ Sekine-Kondo E‚ Shigeura T‚ Motomura Y‚ Yasuda T‚ Satoh R‚ Yoshida H‚ Kubo M Kawamoto H‚ Koseki H‚ Taniguchi M.   Development and Function of Invariant Natural Killer T cells Producing TH2- and TH17-cytokines.
PLoS Biology  2012;   10   (2):   e1001255-

Satoh‚ M.‚ Andoh‚ Y.‚ Clingan‚ S. C.‚ Ogura‚ H.‚ Fujii‚ S.‚ Nakayama‚ T.‚ Taniguchi‚ M.‚ Hirata‚ N.‚ Ishimori‚ N.‚ Tsutsui‚ H.‚ Onoe‚ K.‚ and Iwabuchi‚ K.   Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation‚ steatohepatitis and insulin resistance.
PLoS ONE  2012;   7   (2):   e30568-

Kidoya‚ H.‚ Kunii‚ N.‚ Naito‚ H.‚ Muramatsu‚ T.‚ Okamoto‚ Y.‚ Nakayama‚ T.‚ and Takakura‚ N.   The apelin/APJ system induces maturation of the tumor vasculature and improves the efficiency of immune therapy.
Oncogene  2012;   in press    

Aoyagi‚ Y.‚ Kuroda‚ M.‚ Asada‚ S.‚ Tanaka‚ S.‚ Konno‚ S‚. Tanio‚ M.‚ Aso‚ M.‚ Okamoto‚ Y.‚ Nakayama‚ T.‚ Saito‚ Y.‚ Bujo‚ H.   Fibrin glue is a candidate scaffold for long-term therapeutic protein expression in spontaneously differentiated adipocytes in vitro.
Exp Cell Res.  2012;   318   (1):   8-15

Alexopoulos P‚ Guo LH‚ Tsolakidou A‚ Kratzer M‚ Grimmer T‚ Westerteicher C‚ Jiang M‚ Bujo H‚ Diehl-Schmid J‚ Kurz A‚ Perneczky R.   Interrelations between CSF Soluble AβPPβ‚ Amyloid-β 1-42‚ SORL1‚ and Tau Levels in Alzheimer’s Disease.
J Alzheimers Dis.  2012;   28   (3):   543-552

Gotoda T‚ Shirai K‚ Ohta T‚ Kobayashi J‚ Yokoyama S‚ Oikawa S‚ Bujo H‚ Ishibashi S‚ Arai H‚ Yamashita S‚ Harada-Shiba M‚ Eto M‚ Hayashi T‚ Sone H‚ Suzuki H‚ Yamada N.   Diagnosis and Management of Type I and Type V Hyperlipoproteinemia.
J Atheroscler Thromb.  2012;   19   (1):   1-12

Arai H‚ Ishibashi S‚ Bujo H‚ Hayashi T‚ Yokoyama S‚ Oikawa S‚ Kobayashi J‚ Shirai K‚ Ota T‚ Yamashita S‚ Gotoda T‚ Harada-Shiba M‚ Sone H‚ Eto M‚ Suzuki H‚ Yamada N.   Management of Type IIb Dyslipidemia.
J Atheroscler Thromb.  2012;   19   (2):   105-114

▲PageTop

Books

Jiang X‚ Sugaya S‚ Ren Q‚ Sato T‚ Tanaka T‚ Fujii K‚ Kita K‚ Suzuki N.   Prevention of pancreatic cancer   In Pancreatic Cancer –molecular mechanism and targets- Edited by Sanjay K Srivastava. (InTech‚ Croatia).  2012;      161-174

Suzuki N‚ Kita K‚ Sugita K‚ Fujii K‚ Suzuki T‚ Lu J‚ Isogai E.   Human SOS-related disorder.   In Human SOS book‚ Ed. Suzuki N‚ (Transworld Research Network‚ India).  2012;      23-24

Fujii K‚ Suzuki N‚ Uchikawa H‚ Sugita K‚ Miyashita T.   To SOS science from nevoid basal cell carcinoma syndrome (Gorlin syndrome).   In Human SOS book‚ pp. 49-56. Ed. Suzuki N‚ (Transworld Research Network‚ India)  2012;      49-56

Nohata N‚ Hanazawa T‚ Kinoshita T‚ Okamoto Y‚ Seki N.   MicroRNAs function as tumor suppressors or oncogenes: Aberrant expression of microRNAs in head and neck squamous cell carcinoma.   Auris Nasus Larynx.   2012;  in press    

Watanabe N‚ Nakajima H.   Coinhibitory molecules in autoimmune diseases.   Clin Dev Immunol.  2012;  269756    

Ozawa‚ S.‚ Tachimori‚ Y.‚ Baba‚ H.‚ Fujishiro‚ M.‚ Matsubara‚ H.. Numasaki‚ H.‚ Oyama‚ T.‚ Shinoda‚ M.‚ Takeuchi‚ H.‚ Teshima‚ T.‚ Udagawa‚ H.‚ Uno‚ T.‚ J. Patrick Barron.   Comprehensive Registry of Esophageal Cancer in Japan‚ 2004.   Esophagus  2012;  9   (2):   75-98

Takemoto M‚ Mori S‚ Kuzuya M‚ Yoshimoto S‚Shimamoto A ‚ Igarashi M‚ Tanaka Y‚ Miki T‚ Yokote Y   Diagnostic criteria for Werner syndrome based on Japanese nationwide epidemiological survay.   Geriatr Gerontol Int  2012;  in press    

Tadashi Kamada‚ Hirohiko Tsujii   HIMAC: A New Start for Heavy Ions   Ion Beam Therapy (Biological and Medical Physics‚ Biomedical Engineering ; vol.320)  2012;      611-621

Tadashi Kamada‚ Naoyoshi Yamamoto‚ Masayuki Baba   Carbon Ion Radiotherapy for Perupheral Stage1 Non-Small Cell Lung Cancer   Ion Beam Therapy (Biological and Medical Physics‚ Biomedical Engineering ; vol.320)  2012;      223-228

Fujimura T‚ Okamoto Y‚ Taniguchi M.   Therapeutic effects and biomarkers in sublingual immunotherapy: a review.   J Allergy (Cairo)  2012;      381737--381746

Onouchi‚ Y.   Genetics of Kawasaki Disease   Circulation Journal  2012;  76     1581-1586

▲PageTop

International Conferences

Akutsu‚ Y.‚ Mori‚ M.‚ Matsubara‚ H. A novel Peptide Vaccine Therapy for Esophageal Squamous Cell Carcinoma. 
Fourth Japanese-Mongolian International Cancer Joint Symposium 2012-9-6 Ulaanbaatar/Mongolia

Taniguchi ‚M.‚ fujii‚ S.‚ Motohashi‚ S.‚ Nakayama‚ T. NKT cell-targeted adjuvant cell therapy-from basic to clinic 
14th International Congress of Immunology 2012-8-23 Kobe/Japan

Nohata‚ N. Tumor suppressive microRNA-1 and microRNA-133a cluster regulating molecular targets in head and neck squamous cell carcinoma 
8th International Conference on Head and Neck Cancer 2012-7-21 Toronto/Canada

Takuma Nomiya‚ Souhei Kawashiro*‚ Mayumi Harada*‚ Hiroko Sudo*‚ Ibuki Ota*‚ Mayumi Ichikawa*‚ Yuki Kuroda*‚ Misako Murakami*‚ Kenji Nemoto*‚ Hiroshi Tsuji‚ Tadashi Kamada Analyses of inter- and intra-fractional target motion in the lung using respiratory gating device‚ 
The 6th S. Takahashi Memorial Symposium & The 6th Japan-US Cancer Therapy international Joint Symposium‚ 2012-7-19 Hiroshima/Japan

Horie‚ T. Reversible canalicular Mrp2 localization induced by intracellular redox status 
The 3rd International Conference on Gastroenterology 2012-7-14 Kos Island/Greece

Yoshie Sanayama‚ Kei Ikeda‚ Shinichiro Kagami‚ Shunsuke Furuta‚ Daisuke Kashiwakuma‚ Itsuo Iwamoto‚ Takeshi Umibe‚ Ryutaro Matsumura‚ Takao Sugiyama‚ Makoto Sueishi‚ Yasushi Nawata‚ Masaki Hiraguri‚ Yukari Saito‚ Hiroko Kanari‚ Ken Nonaka‚ Osamu Ohara‚ Hiroshi Nakajima Prediction of clinical response to tocilizumab therapy with comprehensive gene expression analysis of peripheral blood mononuclear cells in patients with rheumatoid arthritis. 
EULAR congress 2012 2012-6-6 Berlin/Germany

Daiki Nakagomi‚ Kei Ikeda‚ Ayako Okubo‚ Taro Iwamoto‚ Yoshie Sanayama‚ Kentaro Takahashi‚ Mieko Yamagata‚ Hiroaki Takatori‚ Kotaro Suzuki‚ Katsuhiko Takabayashi‚ and Hiroshi Nakajima Ultrasonographic assessment of synovitis improves the accuracy of 2010 American College of Rheumatology/ European League Against Rheumatism classification criteria for rheumatoid arthritis to predict development of a methotrexate-requiring disease 
EULAR congress 2012 2012-6-6 Berlin/Germany

Issei Komuro Wnts in development in other pathways“Complement C1q activates canonical Wnt signaling and　Promotes aging-related phenotypes 
EMBO Conference : 30 Years of Wnt Signalling 2012-6-27 Egmond aan Zee/Netherlands

Masami Mukai‚ Yutaka Ando‚ Yasuo Okuda‚ Hiroshi Tsuji‚ Tadashi Kamada Prototype of the Radiation Oncology Teaching Files System for Charged Particle Radiotherapy 
CARS2012 2012-6-27 Pisa/Italy

Yoshida‚ T. Effective treatment of hypothyroidism with powdered medicine and its involvement of efflux transporter BCRP in a patient with multidrug resistance 
ENDO2012 2012-6-24 Houston/USA

Issei Komuro Angiogenesis and heart failure 
17th International Vascular Biology Meeting 2012-6-2 Wiesbaden/Germany

Taniguchi‚ M. NKT Cell-mediated Adjuvant Activity on Antitumor Responses 
FOCIS2012 2012-6-19 Vancouver/Canada

Okamoto Y‚ Inamine A‚ Yonekura S Lactic acid bactera as an effective adjuvant with sublingual immunotherapy for allergic rhinitis. 
第24回ISIAN 2012-6-17 Tolouse/France

Atsuko Kamiichi‚Tomomi Furihata‚Satoshi Kishida‚Shinya Kawamatsu and Kan Chiba ESTABLISHMENT OF NOVEL CONDITIONALLY IMMORTALIZED HUMAN ASTROCYTES:A PROMISING TOOL FOR DEVELOPMENT OF A NEW IN VITRO CO-CULTURE MODEL OF THE BLOOD-BRAIN BARRIER 
19th International Symposium on Microsomes and Drug Oxidations (MDO) and 12thEuropean Regional ISSX Meeting 2012-6-17 Noordwijk aan Zee/The Netherlands

Satoshi Kishida‚Tomomi Furihata‚Atsuko Kamiichi‚Shinya Kawamatsu and Kan Chiba EXAMINATION OF TRANSCYTOTIC RECETOR GENES EXPRESSION IN A NEWLY-DEVELOPED CONDITIONALLY IMMORTALIZED HUMAN BRAIN MICROVASCULAR ENDOTHELIAL CELL LINE 
19th International Symposium on Microsomes and Drug Oxidations (MDO) and 12thEuropean Regional ISSX Meeting 2012-6-17 Noordwijk aan Zee/The Netherlands

Shimojo‚N.Kumemura‚N.Morita‚Y.Tada‚H.Suzuki‚K.Takao I.Kohno‚Y.Kido‚H. Allergen sensitization develops in utero:analysis of allergen-specific antibodies by ahighly-sensitive new allergen microarray. 
EAACI2012 2012-6-16 Geneva/Switzerland

Endo. Y.‚ Nakayama.T. Identification of pathogenic memory Th2 cells that produce IL-5 and regulate allergic airway inflammation. 
European Academy of Allergy and Clinical Immunology Congress 2012 2012-6-16 Geneva/Switzerland

Sei Sai‚ Kazuhiko Oonishi‚ Shigeru Yamada‚ Tadashi Kamada‚ et.al Effects of Carbon Ion Beams on Liver Cancer Stem-Like Cells and Its Comparison with X-rays 
International Society for Stem Cell Research (ISSCR) 10 th Annual Meeting 2012-6-13 Yokohama/Japan

Masashi Koto‚ Azusa Hasegawa‚ Ryo Takagi‚ Akira Fujikawa‚ Takamichi Morikawa‚ Hirohiko Tsujii‚ Tadashi Kamada Risk factors for brain injury after carbon ion radiotherapy for skull base tumors 
European Society for Therapeutic Radiology and Oncology　31 2012-5-9 Barcelona/Spain

Masaru Wakatuki‚ Shingo Kato*‚ Tatsuya Ohno*‚ Kumiko Karasawa‚ Ken Ando‚ Hiroki Kiyohara*‚ Takashi Nakano*‚ Tadashi Kamada‚ Makio Syozu Carbon ion Radiotherapy for locally advanced adenocarcinoma of the uterine cervix 
European Society for Therapeutic Radiology and Oncology　31 2012-5-9 Barcelona/Spain

Makoto Shinoto‚ Shigeru Yamada‚ Kyosan Yoshikawa‚ Shigeo Yasuda‚ Hiroshi Imada‚ Tadashi Kamada Role of FDG-PET as a predictor of distant failure in preoperative Carbon-ion radiotherapy for pancreatic cancer 
European Society for Therapeutic Radiology and Oncology　31 2012-5-9 Barcelona/Spain

Atsuko Kamiichi‚ Tomomi Furihata‚ Miki Nagai‚ Sayaka Matsumoto‚ Seiya Ishii‚ Shinichiro Motohashi‚ Ichiro Yoshino and Kan Chiba A novel variant is a bona fide organic anion　trasporting polypeptide 1B3 in cancer cells 
The 2th Japan-China Symposium on Cancer Research 2012-5-9 Chiba/Japan

Yokote‚ K. Mission of medical research in aging society 
千葉大学と高雄医学大学姉妹校協定締結記念行事 2012-5-5 Kaohsiung/Taiwan

Ito. T CDC42 and NFκB signaling contribute to pro-inflammatory phenotype of senescent endothelial cells 
41st Annual Meeting of The American Aging Association 2012-5-31 Dallas/USA

Masaya Yokota‚ Kotaro Suzuki‚ Koji Tokoyoda‚ Daiki Nakagomi‚ Toshinori Nakayama‚ Hitoshi Kohsaka‚ Itsuo Iwamoto‚ and Hiroshi Nakajima1 Crucial Roles of Mast Cells in a Murine Model of Polymyositis 
AAI Annual Meetings 2012 2012-5-3 Honolulu/USA

Kentaro Takahashi‚ Koichi Hirose‚ Saki Kawashima‚ Yusuke Niwa‚ Hidefumi Wakashin‚ Arifumi Iwata‚ Hiroshi Nakajima IL-22 Attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic inflammation 
AAI Annual Meetings 2012 2012-5-3 Honolulu/USA

Nagato‚ K.‚Motohashi‚ S. Nakayama‚T. Accumulation of activated invariant NKT cells in the tumor microenvironment after α-galactosylceramide-pulsed antigen presenting cells. 
Clinical Immunology Society (CIS) Annual Meeting 2012-5-17 Chicago/USA

Kumiko Karasawa‚ Masaru Wakatuki‚ Ken Ando‚ Shingo Kato‚ Hiroki Kiyohara‚ Tadashi Kamada Carbon Ion Radiotherapy For Gynecological Melanoma 
51st Annual Meeting of Particle Therapy Co-Operative Group 2012-5-14 Seoul/Korea

Shigeru Yamada‚ Makoto Shinoto‚ Koutaro Terashima‚ Shigeo Yasuda‚ Hiroshi Imada‚ Tadashi Kamada‚ Hirohiko Tsujii Shinichiro Mori: Pancreas / Rectum 
53rd Annual Meeting of Particle Therapy Co-Operative Group 2012-5-14 Seoul/Korea

Sei Sai‚ Kazuhiko Oonishi‚ Shigeru Yamada‚ Tadashi Kamada Effects of Carbon Ion Beam on Pancreatic Cancer Stem-Like Cells In Vitro and In Vivo 
52nd Annual Meeting of Particle Therapy Co-Operative Group 2012-5-14 Seoul/Korea

Tadashi Kamada Pencil Beam Scanning with Carbon Ion at NIRS-HIMAC 
51st Annual Meeting of Particle Therapy Co-Operative Group 2012-5-14 Seoul/Korea

Tadashi Kamada Carbon ion radiotherapy at NIRS-HIMAC 
Clinical protocols and fractionation regimen‚ Department of radiation oncology grand rounds 2012-5-1 New York/USA

Yokote‚ K. Cellular regulation in diabetic complications 
2012 Shanghai Symposium on Obesity and Diabetes 2012-4-7 Shanghai/China

Shigeru Yamada‚ Makoto Shinoto‚ Satoshi Endo‚ Shigeo Yasuda‚ Hiroshi Imada‚ Tadashi Kamada‚ Hirohiko Tsujii Carbon Ion Radiotherapy for Patients with Locally Recurrent Rectal Cancer and Pancreatic Cancer‚ 
New Frontiers in Cancer Treatment 2012-4-26 Colorado/USA

Tadashi Kamada Current Status and Future Prospects for Carbon Ion Therapy World-wide 
New Frontiers in Cancer Treatment 2012-4-26 Colorado/USA

Naoyoshi Yamamoto‚ Masayuki Baba‚ Mio Nakajima‚ Kyosan Yoshikawa‚ Naruhiro Matsufuji‚ Shinichi Minohara*‚ Hiroshi Tsuji‚ Tadashi Kamada‚ Hirohiko Tsujii Carbon Ion Radiotherapy in a Hypofraction Regimen for Stage I Non-Small Cell Lung Cancer 
New Frontiers in Cancer Treatment 2012-4-26 Colorado/USA

Hiroshi Tsuji‚ Nobutaka Mizoguchi‚ Shingo Toyama‚ Tadashi Kamada‚ Hirohiko Tsujii Carbon Ion Radiotherapy for prostate cancer 
New Frontiers in Cancer Treatment 2012-4-26 Colorado/USA

Shigeru Yamada‚ Makoto Shinoto‚ Satoshi Endo‚ Koutaro Terashima‚ Shigeo Yasuda‚ Hiroshi Imada‚ Tadashi Kamada‚ Hirohiko Tsujii Carbon Ion Radiotherapy for Patients with Locally Recurrent Rectal Cancer 
New Frontiers in Cancer Treatment 2012-4-26 Colorado/USA

Shigeru Yamada‚ Makoto Shinoto‚ Koutaro Terashima‚ Shigeo Yasuda‚ Hiroshi Imada‚ Tadashi Kamada‚ Hirohiko Tsujii Carbon Ion Radiotherapy for Pancreatic Cancer 
New Frontiers in Cancer Treatment 2012-4-26 Colorado/USA

Tanzawa‚H Targeting gene therapies enhance sensitivity in chemo- and/or radio-therapy of oral cancer. 
The 53th Congress of the Korean Society of Oral and Maxillofacial Surgeons 2012-4-26 江原道/韓国

Nakayama‚ T. Pathogenic memory Th2 cells in airway inflammation. 
novo nordisk innovation summit Tokyo 2012 chronic inflammation and autoimmune diseases 2012-4-17 Tokyo/Japan

Okamoto Y． Alternatie　Medicine for allerge rhinitis. 
The 14th Japan-Korea Joint Meeting of Otorhinolaryngology/Head & Neck Surgey  2012-4-12 Kyoto/Japan

Nohata‚ N. Identification of Novel Tumor Suppressive microRNAs in Head and Neck Squamous Cell Carcinoma. 
The 14th Japan-Korea Joint Meeting of Otorhinolaryngology/Head & Neck Surgey  2012-4-12 Kyoto/Japan

Toyoyuki Hanazawa microRNA-874 as a tumor suppressor in maxillary sinus squamous cell carcinoma based on microRNA expression signature 
AACR2012 2012-3-31 Chicago/USA

Kinoshita‚ T. Molecular networks regulated by tumor suppressive microRNA-375 in head and neck squamous cell carcinoma 
AACR2012 2012-3-31 Chicago/USA

Nohata‚ N. Molecular networks regulated by tumor suppressive microRNA-1 and microRNA-133a in head and neck squamous cell carcinoma 
AACR2012 2012-3-31 Chicago/USA

Shinoda K. CD69 regulates the formation of resting T helper memory 
14th International Conference on Lymphocyte Activation and Immune Regulation 2012-3-3 NewPort Beach/USA

Taniguchi‚ M. NKT cell subsets and their function 
Meeting of the International PhD Program in Immunopharmacology 2012-3-28 Palermo/Italy

Kei Ikeda‚ Daiki Nakagomi‚ Junichi Hosokawa‚ Mieko Yamagata‚ Hiroshi Nakajima. Optic neuropathy associated with Churg-Strauss syndrome: a report of two cases. 
APVAS 2012-3-28 Tokyo/Japan

Yokote‚ K.. Lipid management guideline in Japan 
XVI International Symposium on Atherosclerosis 2012-3-26 Sydney/Australia

Tadashi Kamada arbon Ion RT at NIRS: Clinical protocols and fractionation regimen 
ESTRO Teaching Course on Protons and Ions 2012-3-25 Uppsala/Sweden

Ito. T CDC42 and NFκB signaling contribute to pro-inflammatory phenotype of senescent endothelial cells 
Keystone Symposia symposium:Molecular Basis of Vascular Inflammation and Atherosclerosis (C7) 2012-3-25 Big Sky/USA

Horie‚ T. Oxidative stress and Hepatotoxicity 
The　5th　International　Symposium　for　Future　Technology　Creating　Better Human　Health　and　Society 2012-3-15 Okayama/Japan

Okamoto Y. Research and development of the new treatment against allergic rhinitis in Japan 
第43回韓国鼻科学会 2012-3-11 Seoul/Korea

Onouchi‚ Y.‚ Ozaki‚ K.‚ Suzuki‚ H.‚ Terai‚ M.‚ Hata‚ A.‚ Tanaka‚ T. ITPKC and CASP3 polymorphisms and risks for IVIG unresponsiveness and coronary artery lesion formation in Kawasaki disease 
Human Genome Meeting 2012 2012-3-11 Sydney/Australia

Taniguchi‚ M. Subsets of NKT cells 
The 4th Joint RCAI-LIAI Workshop Program 2012-2-7 San Diego/USA

Onouchi‚ Y. Genome-wide association study identified new susceptibility loci for Kawasaki disease -We have found milestones but still have far to go- 
10th International Kawasaki Disease Symposium 2012-2-7 Kyoto/Japan

Okabe‚ E Incidence and characteristics of metabolic disorders and vascular complications in Werner syndrome patients in Japan 
International Conference on Orphan Drugs and Rare Diseases 2012-2-5 Tokyo/Japan

Shigeru Yamada‚ Makoto Shinoto‚ Azusa Hasegawa‚ Naoyoshi Yamamoto‚ Shigeo Yasuda‚ Reiko Imai‚ Hiroshi Tsuji‚ Tadashi Kamada Recent clinical results on heavy ion radiotherapy 
Sugárterápia a klinikai gyakorlatban　III （第３回臨床診療における放射線治療） 2012-2-3 Debrecen/Hungary

Endo Y. Eomesodermin controls IL-5 production in memory Th2 cells through the inhibition of GATA3 activity 
14th International Conference on Lymphocyte Activation and Immune Regulation 2012-2-3 Newport Beach/USA

Naoyoshi Yamamoto‚ Masayuki Baba‚ Mio Nakajima‚ Kyosan Yoshikawa‚ Naruhiro Matsufuji‚ Shinichi Minohara‚ Hiroshi Tsuji‚ Tadashi Kamada‚ Hirohiko Tsujii Carbon Ion Radiotherapy in a Hypo-fraction Regimen for Stage I Non-Small Cell Lung Cancer 
NIRS-KFSHRC Joint Symposium on Carbon Ion Radiotherapy and Radiation Emergency Medicine 2012-2-27 Riyadh/Saudi Arabia

Hiroshi Tsuji‚ Nobutaka Mizoguchi‚ Shingo Toyama‚ Tadashi Kamada‚ Hirohiko Tsujii Carbon Ion Radiotherapy for prostate and liver 
NIRS-KFSHRC Joint Symposium on Carbon Ion Radiotherapy and Radiation Emergency Medicine 2012-2-27 Riyadh/Saudi Arabia

Shigeru Yamada‚ Makoto Shinoto‚ Shigeo Yasuda‚ Hiroshi Imada‚ Tadashi Kamada‚ Hirohiko Tsujii Carbon Ion Radiotherapy for Patients with Locally Recurrent Rectal Cancer and Pancreatic Cancer 
NIRS-KFSHRC Joint Symposium on Carbon Ion Radiotherapy and Radiation Emergency Medicine 2012-2-27 Riyadh/Saudi Arabia

Azusa Hasegawa‚ Masashi Koto‚ Ryo Takagi‚ Akira Fujikawa‚ Takamichi Morikawa‚ Tadashi Kamada‚ Hirohiko Tsujii Carbon Ion Radiotherapy for Malignant Head-and-Neck Tumors 
NIRS-KFSHRC Joint Symposium on Carbon Ion Radiotherapy and Radiation Emergency Medicine 2012-2-27 Riyadh/Saudi Arabia

Ikeuchi T‚ Hirayama S‚ Miida T‚ Tokutake T‚ Yajima R‚ Jiang M‚ Bujo H‚ Nishizawa M Quantification of soluble LR11/SorLA in CSF and plasma of patients with Alzheimer disease 
Keystone Symposia - ApoE‚ Alzheimer’s‚ and lipoprotein biology 2012-2-23 Keystone/USA

Kazuhiko Oonishi‚ Hiroshi Imada‚ Shigeo Yasuda‚ Shigeru Yamada‚ Makoto Shinoto‚ Satoshi Endo‚ Tadashi Kamada‚ Osamu Yokosuka Efficacy and safety of short-course carbon ion radiotherapy for elderly hepatocellular carcinoma patients 
The 22nd Congress of the Asian Pacific Association for the Study of the Liver 2012-2-16 Taipei/Taiwan

Watanabe K‚ Suzuki H‚ Haniu H‚ Numano F‚ Saitoh A‚ Uchiyama M‚ Bujo H Soluble LR 11: a novel biomarker for vascular lesion development late after Kawasaki disease 
The 10th International Kawasaki Disease Symposium 2012-2-16 Kyoto/Japan

Kazuhiko Onishi‚ Hiroshi Imada‚ Shigeo Yasuda‚ Shigeru Yamada‚ Makoto Shinoto‚ Satoshi Endo‚ Tadashi Kamada‚ Osamu Yokosuka Efficacy and safety of short-course carbon ion radiotherapy for elderly hepatocellular carcinoma patients‚ 
The 22nd Congress of the Asian Pacific Association for the Study of the Liver 2012-2-16 Taipei/Taiwan

Yoshida Y‚ Minamino T Notch signaling positively regulates vascular endothelial cell senescence 
Gordon Research Conference‚ Aging‚ Biology of 2012-2-12 Ventura/USa

Ishibashi‚ R . Semaphorin3g regulates endothelial cell fenestration and the structure of podocyte foot processes 
48th EASD Annual Meeting 2012-10-5 Berlin/Germany

Motegi‚ H . 1‚5-anhydroglucitol is useful for an assessment of glycemic excursion and short-term improvement of glycemic control correlating with an evaluation by continuous glucose monitoring system 
8th Asian-Pacific Society of Atherosclerosis and Vascular Disease 2012-10-20 Phuket/Thailand

Yokote‚ K . Lipid management guideline in A-P region. 
8th Asian-Pacific Society of Atherosclerosis and Vascular Disease 2012-10-20 Phuket/Thailand

Yokote‚ K . Familial hypercholesterolemia‚ model of care in Asian-Pacific region. 
8th Asian-Pacific Society of Atherosclerosis and Vascular Disease 2012-10-20 Phuket/Thailand

Hanari‚ N.‚ Mori‚ M.‚ Horibe‚ D.‚ Gunji‚ H‚ Kawahira‚ H.‚ Hayashi‚ H.‚ Matsubara‚ H. Intracorporeal reconstraction after laparoscopic distal gastrectomy and total gastrectomy for gastric cancer. 
19th China-Japan Joint Congress for Gastroenterological Surgery 2012-10-20 Shanghai/China

Mori‚ M.‚ Hanari‚ N.‚ Horibe‚ D.‚ Gunji‚ H.‚ Kawahira‚ H.‚ Hayashi‚ H.‚ Matsubara‚ H. Current status of laparoscopic surgery for gastric submucosal tumors in our institution. 
19th China-Japan Joint Congress for Gastroenterological Surgery 2012-10-20 Shanghai/China

Nishimori‚ T‚ Miyauchi‚ H.‚ Suzuki‚ K.‚ Ohira‚ G.‚ Tohma‚ T.‚ Hanari‚ N.‚ Mori‚ M.‚ Matsubara‚ H. Preoperative chemoradiotherapy for advanced lower rectal cancer. 
19th China-Japan Joint Congress for Gastroenterological Surgery 2012-10-20 Shanghai/China

Matsubara‚ H. Surgical treatment of gastric cancer: Current situation in Japan. 
19th China-Japan Joint Congress for Gastroenterological Surgery 2012-10-20 Shanghai/China

Motegi‚ H. 1‚5-anhydroglucitol is useful for an assessment of glycemic excursion and short-term improvement of glycemic control correlating with an evaluation by continuous glucose monitoring system 
8th Asian-Pacific Society of Atherosclerosis and Vascular Disease 2012-10-20 Phuket/Bangkok

Osamu Ohara Integra1ve Medical Sciences at RIKEN RCAI: to understand the process of disease development 
Australia-Japan workshop on biomedical breakthroughs and systems biology 2012-10-16 Tokyo/Japan

Hoshino‚ I.‚ Akutsu‚ Y.‚ Komatsu‚ A.‚ Hanari‚ N.‚ Mori‚ M.‚ Yoneyama‚ Y.‚ Akanuma‚ N.‚ Isozaki‚ Y.‚ Maruyama‚ T.‚ Takeshita‚ N.‚ Matsubara‚ H. Antitumor effects of novel histone demethylase inhibitor on esophageal squamous cell carcinoma. 
13th World Congress of the International Society for Diseases of the Esophagus 2012-10-15 Venice/Italy

Hoshino‚ I. Maruyama.T.‚ Akutsu‚ Y.‚ Komatsu‚ A.‚ Hanari‚ N.‚ Mori‚ M.‚ Yoneyama‚ Y.‚ Akanuma‚ N.‚ Isozaki‚ Y.‚ Takeshita‚ N.‚ Hayashi‚ H.‚ Tamura‚ Y.‚ Toyota‚ T.‚ Matsubara‚ H. Staging laparoscopy with near-infrared flourescence imaging using synthesized indocyanine green liposomal derivative. 
13th World Congress of the International Society for Diseases of the Esophagus 2012-10-15 Venice/Italy

Akutsu‚ Y.‚ Hanari‚ N.‚ Hoshino‚ I.‚ Kono‚ T.‚ Uesato‚ M.‚ Shuto‚ K.‚ Natsume‚ T.‚ Hayashi‚ H.‚ Mori‚ M.‚ Matsubara‚ H. The outcome of laparoscopic surgery with and without short gastric vessel division for achalasia. 
13th World Congress of the International Society for Diseases of the Esophagus 2012-10-15 Venice/Italy

Akutsu‚ Y.‚ Yasuda‚ S.‚ Nagata‚ M.‚ Izumi‚ Y.‚ Okazumi‚ S.‚ Shimada‚ H.‚ Nakatani‚ Y.‚ Tsujii‚ H.‚ Kamada‚ T.‚ Yamada‚ S.‚ Matsubara‚ H. A phase 場J/場Kclinical trial of preoperative short-course carbon-ion radiotherapy for patients with squamous cell carcinoma of the esophagus. 
13th World Congress of the International Society for Diseases of the Esophagus 2012-10-15 Venice/Italy

Akutsu‚ Y.‚ Shuto‚ K.‚ Uesato‚ M.‚ Kono‚ T.‚ Hoshino‚ I.‚ Shiratori‚ T.‚ Isozaki‚ Y.‚ Akanuma‚ N.‚ Matsubara‚ H. The number of metastati lns is a significant prognostic factor for esophageal cancer patients treated with neoadjuvant chemoradiotherapy. 
13th World Congress of the International Society for Diseases of the Esophagus 2012-10-15 Venice/Italy

Okazumi‚ S.‚ Shuto‚ K.‚ Matsubara‚ H.‚ Kato‚ R. The cancer cell amont in lymph node metastasis of esophageal cancer evaluated by contrast enhanced MD-CT pattern or fdg-pet uptake and its clinical significance. 
13th World Congress of the International Society for Diseases of the Esophagus 2012-10-15 Venice/Italy

Okazumi‚ S.‚ Shuto‚ K.‚ Matsubara‚ H.‚ Kato‚ R. Preoperative estimation of curative resection for advanced esophageal cancer with adjacent organ invasion after chemoradiation by qualitative response evaluation using 3D-volume rendered MD-CT. 
13th World Congress of the International Society for Diseases of the Esophagus 2012-10-15 Venice/Italy

Nakano‚ T. Inoue‚ Y. Shimojo‚ N. Kohno‚ Y. Expression of hsa-mir15a‚ which is a candidate microRNA regulating VEGFA expression‚ is lower in CD4+ T cells in pediatric asthma patients 
29th Symposium of the Collegium Internationale Allergolgicum 2012-10-14 Cheju/Korea

Ishikawa‚ T . Investigation of the podocyte-secreted protein R3h domain containing-like in diabetic nephropathy 
48th EASD Annual Meeting 2012-10-1 Berlin/Germany

Ishibashi‚ R . Semaphorin3g regulates endothelial cell fenestration and the structure of podocyte foot processes 
48th EASD Annual Meeting 2012-10-1 Berlin/Germany

Ishikawa‚ T . Investigation of the podocyte-secreted protein R3h domain containing-like in diabetic nephropathy 
48th EASD Annual Meeting 2012-10-1 Berlin/Germany

Tomomi Furihata‚ Miki Nagai‚ Seiya Ishii‚ Sayaka Matsumoto、Shinichiro Motohashi‚ Ichiro Yoshino‚ Kan Chiba A novel variant is a bona fide organic anion transporting polypeptide 1B3 in cancer cells 
International Symposium on PPF of Molecular Pharmacokinetics 2012-1-16 Tokyo/Japan

Satoshi Kishida‚Tomomi Furihata‚Atsuko kamiichi‚Shinya Kawamatu‚ Kan Chiba Establishment and functional characterization of a novel conditionally immortalized human brain microvascular endothelial cell line 
International Symposium on PPF of Molecular Pharmacokinetics 2012-1-16 Tokyo/Japan

▲PageTop

• 
• 
• 
• 
• 
• 
• 
• 
• 
• 
• 

Copyright(C) 2008 Chiba University All Rights Reserved.